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ImmunoSensation - the immune sensory system

Cluster Publication in Journal of Neuroscience by Prof. Beck

June 01, 2018

 

A new publication by our Cluster member Prof. Heinz Beck shows, why the worldwide leading medication against epilepsy might not be suitable for a lot of patients.
The new findings published in the Journal of Neuroscience could lead to better and more effective therapies against epilepsy. This is of high importance since every third patient is not responding to the prescripted drugs these days.

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Transregio Nucleic Acid Immunity funded by DFG

May 21, 2018

 

The new Transregio 'Nucleic Acid Immunity' from the Unversity Bonn, TU Dresden and LMU Munich is funded by the DFG for a first round of 4 years from July 1st on.
Prof. Gunther Hartmann is the speaker of this consortium of researcher who will investigate the molecular mechanisms of recognizing foreign nucleic acids by our immune system.
This is of special importance since the malfunction of this system leads to various diseases such as chronic viral infections, inflammation and autoimmune disorders.
11 research groups of the medical faculty from the University Bonn are participating in this Transregio.

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Night of Science- Wissenschaftsnacht

May 17, 2018 - May 18, 2018

 

Every alternate year in Bonn, Bonner Wissenschaftsnacht (Night of Science) is held at the Münsterplatz-Bonn. We at the Cluster of Excellence ImmunoSensation, joined other scientist from Bonn, Rhein-Sieg-Kreis and Kreis-Ahrweiler at the tent in Münsterplatz to contribute to the theme on Circulation. Using a torso from the Institute of Anatomy- University of Bonn and a chimpanzee skull from Museum König, cluster scientists explained the T-cell immune response invoked during HIV infection to members of the public. The chimpanzee skull was representative of the non-human primates that can be infected with a Lentivirus similar to HIV the SIV (Simian Immunodeficiency Virus). The scientist used microscopes to show immune cells in different organs using tissue sections mounted on slides.
We sincerely thank; Cluster members and scientists for their support, Bonner Wissenschaftsnacht for the opportunity to participate, Institute of Anatomy-University of Bonn for the torso, Museum König for the chimpanzee skull, the volunteers from Prof. Latz's group- Institute for Innate Immunity, Prof. Kolanus- LIMES institute, for the tissue section and Institute of Medical Microbiology Immunology and Parasitology for the Microscopes. 

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Lamas and Alpacas as a tool for immunological research

May 16, 2018

 

Proteins are highly important for lots of processes in our body. To gain more knowledge about their function, researchers would like to modify or completey remove them from our body.
Our Cluster researcher Dr. Florian Schmidt, group leader of an Emmy Noether-Research group at the Institute of Innate Immunity is further developing a method for designing protein-blockers with the help of Alpacas and Lamas.
You can find the german press release here.
Contact:
Dr. Florian I. Schmidt
Emmy Noether-Group Leader
Institute of Innate Immunity
University of Bonn
Tel. 0228/28751124
E-Mail: fschmidt@uni-bonn.de


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New DFG Statement of the replicability of research results

May 08, 2018

 

The German Research Council announced its new statement for the replicability of research results in the field of medicine and biomedicine.
You can find the german press release from the DFG website here.
The statement can be found on our homepage - although it is only in german.
http://www.immunosensation.de/press_media/links_downloads.html

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Kinderuni - Do cells have eyes? Can cells see?

May 07, 2018 - May 07, 2018

 

Prof. Dagmar Wachten from the Institute of Innate Immunity, University of Bonn, gave an intriguing lecture to young enthusiastic 8-13 year olds, who were participants in the Kinderuni program. Do cells have eyes? (’’Können Zellen gucken’’) was the topic of her lecture, which stimulated the minds of the young participants, resulting in questions and discussions. Photos can be found on this link.

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Day of Immunology 2018

May 05, 2018

 

Scientists from the ImmunoSensation Cluster of Excellence took time to share interesting, new and current research with members of the public at Bonn Marktplatz to mark the Day of Immunology. On that fine sunny spring Saturday, residents from Bonn and the surrounding visited the ImmunoSensation tent and asked questions related to immunology of the presented disciplines. To spice the day up, 5 public talks were held in 3 different locations, and attendees were not shy to ask the presenters questions, which was a confirmation that the talks were a success.
At the end of the day, cluster scientists and members of the public had a nice ImmunoSensational day. We sincerly thank the Bundesstadt Bonn- Economic Development Office for letting us on the Marktplatz.

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Cluster publication in Nature Genetics

April 30, 2018

 

Cluster member Prof. Markus Nöthen and colleagues published with an international consortium 30 new gene loci that are connected with depression.
The recent publication was released in Nature Genetics and integrated the data of 135.000 patients and 344.000 healthy controls.
Find the german press release here.
Publication: Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression, Nature Genetics, DOI: 10.1038/s41588-018-0090-3

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Ringvorlesung: Herausforderungen der biomedizinischen Forschung

April 05, 2018

 

The Cluster of Excellence ImmunoSensation is proud to share with you, that we organize a lecture series about challengens in the biomedical research field.
We invite you to join us on different dates from april 17 until june 12 in the Main Building of the University Bonn, Lecture Hall 1.
It starts 6.30 pm and you can bring your non-english speaking friends since the lectures are always in german. Afterwards there is time to ask questions.

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New member of the CCO Team

April 04, 2018

 

We are happy to announce that we have a new colleague in the Cluster Coordination Office.
Dr. Alexandra Krämer will be in charge for the IITB support within the CCO.
Do not hesitate to get in contact with Dr. Alexandra Krämer if you need advice regarding the IITB program.
You can contact her via alexandra.kraemer@uni-bonn.de or 0228 287 51182.
Welcome on board Alexandra.
Your CCO Team

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New competence network 'West German Genome Center'

March 19, 2018

 

The 'West German Genome Center' (WGGC) is a new initiative of the University of Bonn, University of Cologne and the Heinrich-Heine-University Düsseldorf. 
This new competence network is being funded with 5.3 Million Euro for three years by the German Research Foundation. It is the first infrastructure facility for the Areas of Bioinformatics, Genomics and High Throughput Computing.
Find the german press release here.

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Seminars by Next Generation Sequencing Core Facility

March 14, 2018

 

Dear Cluster member and Cluster scientist,

The Next Generation Sequencing (NGS) Core Facility invites you to two technical seminars: 

Topic: Chromium Single Cell 3¹ v2 - Application and protocol overview 

Date and time: Thursday, March 22, 2018 from 9:00 am to 11:00 am 

Location: Life & Brain, seminar room 


								
Topic: Theory refresher and software overview - Cell Ranger - Loupe Cell Browser 

Date and time: Friday, March 23, 2018 from 1:00 pm to 3:00 pm 

Location: Life & Brain, seminar room 

The seminars will be held by the company 10X Genomics. No registration! 

For more information, please contact Dr. rer. nat. André Heimbach (heimbach@uni-bonn.de), Head of NGS Core Facility.

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Roofing ceremony for new Cluster building

March 09, 2018

 

The roofing ceremony for our new cluster building - BMZ II - took place this Wednesday.
The BMZ II will host lab and office space for basic research in the field of immunology and infectiology. Also translational and clinical research areas can be found on the 4500 square meter. If everything goes as planned, the building will be opened in the 2nd quarter of 2019.
You can read here the german press release.

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IITB Students' Network Meeting

March 01, 2018

 

Speaker
Most recent scientific highlights within the Cluster of Excellence ImmunoSensation
Invited scientists of different career levels in a round table discussion about job
perspectives in science
Date & Time
Monday, March 12 2018, 2 pm (1pm until 5 pm)
Location
Haus Venusberg
Haager Weg 28-30, 53127 Bonn
Find the program here.
To register, use our online registration tool: http://community.ukb.uni-bonn.de/conftool

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We were a part of the Science Rallye Bonn

February 26, 2018

 

We took part in the Science Rallye of the University Bonn and teamed up with the LIMES Institut.
Together with the group of Prof. Günter Mayer (http://www.mayerlab.de/) we let the participants investigate in a case of murder - of course only a fictional one.
Have a look at the video here.
The next Science Rallye will take place February 9th, 2019 and we will for sure be a part again.

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Western Diet enhances Inflammation - Cell Publication

January 12, 2018

 

The immune system reacts similarly to a high fat and high calorie diet as to a bacterial infection. This is shown by a recent study led by the Cluster member Prof. Dr. Eicke Latz, who is director of the Institute of Innate Immunity Bonn.
Particularly disturbing: Unhealthy food seems to make the body’s defenses more aggressive in the long term. Even long after switching to a healthy diet, inflammation towards innate immune stimulation is more pronounced. These long-term changes may be involved in the development of arteriosclerosis and diabetes, diseases linked to Western diet consumption. The results will be published in the journal ‘Cell’.
“Genomic studies did, in fact, show that the Western diet had activated a large number of genes in the progenitor cells. The genes affected included those responsible for proliferation and maturation“, explains cluster member Prof. Dr. Joachim Schultze from the Life & Medical Sciences Institute (LIMES) and the German Center for Neurodegenerative Diseases (DZNE).
Publication: Anette Christ, Patrick Günther, Mario A.R. Lauterbach , Peter Duewell, Debjani Biswas, Karin Pelka, Claus J. Scholz, Marije Oosting, Kristian Haendler, Kevin Baßler, Kathrin Klee, Jonas Schulte-Schrepping, Thomas Ulas, Simone J.C.F.M. Moorlag, Vinod Kumar, Min Hi Park, Leo A.B. Joosten, Laszlo A. Groh, Niels P. Riksen, Terje Espevik, Andreas Schlitzer, Yang Li, Michael L. Fitzgerald, Mihai G. Netea, Joachim L. Schultze und Eicke Latz: Western diet triggers NLRP3-dependent innate immune reprograming; Cell, 11.1.2018, DOI: 10.1016/j.cell.2017.12.013
Find the german press release here and the english press release here.

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Open spots for the Translational Immunology School

January 08, 2018

 

Dear Cluster members and associated scientists,
we would like to announce that we have a limited number of Cluster fellowships for the Translational Immunology School (TIS) 2018. 
You can apply for a fellowship that covers travel costs and the registration fee, including courses, accommodation, full board and social program.
What? Translational Immunology School (please find more information here: http://web.dgfi.org/translational-school/2018/index.html and in the attachment)
When? March 15 – 17, 2018 
Where? Resort Schwielowsee - Potsdam
For whom? Cluster PhD students and postdocs
Application deadline? January 12, 2018
What do I have to do to apply for a fellowship?
Send a letter of motivation, a letter of recommendation and an abstract (in word format) before January 12, 2018 to c.drescher@uni-bonn.de
If you would like to apply but can’t submit your documents until Friday, January 12, please contact Catherine Drescher.

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Cluster member Heneka publishes in Nature

December 21, 2017

 

Another great publication completes this fantastic year 2017.
Cluster member Prof. Heneka from the German Center for Neurodegenerative Diseases (DZNE) and his colleagues could publish their findings in the well-known Journal Nature.
According to a study now published in the journal “Nature”, inflammatory mechanisms caused by the brain’s immune system drive the progression of Alzheimer’s disease. These findings, which rely on a series of laboratory experiments, provide new insights into pathogenetic mechanisms that are believed to hold potential for tackling Alzheimer’s before symptoms manifest. The researchers envision that one day this may lead to new ways of treatment. Further institutions both from Europe and the US also contributed to the current results.
Congratulations to this amazing achievement!
Publication: “Microglia-derived ASC specks cross-seed ß-amyloid in Alzheimer’s disease”, Carmen Venegas, Sathish Kumar et al., Nature (2017), DOI: 10.1038/nature25158
Find the german press release here and the english press release here.

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Immunity Publication by Prof. Schultze and Dr. Schlitzer

December 20, 2017

 

A new study by cluster member Prof. Joachim Schultze and Dr. Andreas Schlitzer was recently published in the renowned journal Immunity.
When the immune system mobilizes its troops, antigen-presenting cells play an important role. They can emerge from white blood cells (monocytes) that circulate in the blood. An international research team under the leadership of the University of Bonn has now taken a closer look at these important helpers. The research revealed that the monocyte-derived cells are not identical descendants, but rather a very diverse mixture. This finding is important for the further development of tailor-made immunotherapies for combating tumor cells.
Publication: Cellular differentiation of human monocytes is regulated by time-dependent IL4 signalling and NCOR2, Immunity, DOI: 10.1016/j.immuni.2017.11.024

Find the german press release here and the english press release here.

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We are looking for a Data Scientist in Bioinformatics and Systems Biology

December 19, 2017

 

The Cluster of Excellence ImmunoSensation is looking for a Data Scientist in Bioinformatics and Systems Biology.
Have a look here to find further information about the job posting.
http://www.immunosensation.de/career/recruitment.html

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