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ImmunoSensation - the immune sensory system

Six Excellence Clusters for the University of Bonn!!

September 27, 2018 - September 27, 2018


The much awaited Excellence Strategy funding decision by the DFG was received with cheers and applause! As the Rector of the University of Bonn, Prof. Michael Hoch, read the list of the 6 funded Excellence Clusters from the DFG website, the room was filled with joy and cheers!
ImmunoSensation2 and 5 other Clusters were successful in their application. This was a significant moment, as the University of Bonn was the only University in Germany to receive funding for six Clusters of Excellence.  
We congratulate all ImmunoSensation scientists for their hard work and we look forward to achieving greater heights!!
We also congratulate: The Hausdorff Center for Mathematics, Beyond Slavery and Freedom, PhenoRob, ML4Q and ECONtribute!


Cluster scientists discover new role of CCL17

September 12, 2018


ImmunoSensation Cluster scientists and associated members discover a new role for the allergy driver: It influences signal transmission in the brain.
The chemotactic protein CCL17 attracts immune cells to where they are currently needed. Doctors have long known: A high level of this substance in the body indicates an allergic reaction. A team of scientists led by the University of Bonn has now discovered a completely new function: CCL17 also influences signal transmission in the brain. There may even be a molecular link to autism. The results have now been published in the journal “GLIA”.
The article which they published in Glia is available online DOI: 10.1002/glia.23507


ImmunoSensation and the Biomedicine team win the Excellence Science Slam!!

August 27, 2018


The two Excellence Clusters of the University of Bonn, ImmunoSensation and Hausdorff Center for Mathematics organized a joint Science- Slam that was held at the Arkadenhof of the University of Bonn. The slam also received support from the student iGEM-Team Bonn. 
The two teams went head to head, with each having 3 slammers from all over Germany that who presented on their respective disciplines. In the end, the public was charged with the task of determining the winner through casting of beads. And through a clear vote, measured  on measuring cylinders ImmunoSensation and its biomedicine team won. Roman Stilling who presented on microbiome was selected as the slammer of the night. 


Cluster Scientist Nicole Glodde wins Fleur Hiege- Prize 2018

August 24, 2018


Dr. Nicole Glodde from the Institute of Clinical Chemistry and Pharmacology, at the University Hospital Bonn has been selected for the Fleur Hiege-Gedächtnispreis 2018.

The 32-year-old postdoc in the Lab of Prof. Michael Hölzel, will receive the prize in recognition of her work in the field of cancer research that was published in Immunity, 2017. The publication entitled “Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy”, demonstrated that neutrophils acquire immunosuppressive properties and inhibit the activity of killer immune cells, known as cytotoxic T cells, in the context of cancer immunotherapy. By elegantly performed experiments, Glodde and her colleagues discovered a way to counteract this mechanism and to increase the efficacy of cancer immunotherapy.
This is the second time that a cluster scientist has won this prestigious prize! in 2014, Tobias Bald received the same prize! Congratulations Nicole Glodde and the entire Prof. Hölzel lab!


Immunosciences and infection takes 1st position in NRW, DFG funding period 2014-2016

July 26, 2018


The efforts of Cluster scientists is very well reflected with the increase in funding, as shown by the DFG funding atlas. The DFG funding atlas for the period 2014 -2016 places us in 1st position in NRW and 3rd in the whole of Germany. During the 2014-2016 funding period, we received a total of 19.7 million euros, which was 3.4 million more than in 2011-2013 period.
The Medical Faculty was standing strong among the Top 10 in Germany (9 out of 85) having raised a total of 60.4 million euros. Neurosciences also moved up to position 7, having received a total of 16.3 million.
Congratulations for all the hard work!
Find the full press release here.


forsch Uni-Bonn features 3 cluster scientist in the summer 2018 edition

July 16, 2018


The forsch magazine is a publication of the University of Bonn featuring interesting and top ongoing research in various disciplines at the University. 
The 2018 summer edition featured articles from 3 cluster scientist:
Dr. Florian Schmidt on his Nanobodies research and their generation using Alpacas (pg. 22), Prof. Dr. Heinz Beck research on new Epilepsy medication (pg. 28) and Prof. Dr. Markus Nöthen research together with the International Psychiatric Genomics Consortium on genes connected to depression  (pg 32)
Online copies are available available both as soft and hardcopies,Link to forsch


10 million euros for young cancer researchers

July 05, 2018


The Centre for Integrated Oncology (CIO) Köln/Bonn receives one of the five new " Mildred-Scheel-Nachwuchszentren" with which the German Cancer Aid (DKH) aims to keep cancer research in Germany fit for the future. CIO Köln/ Bonn will hence receive two million euros per year for five years, this money will be available to the young cancer scientists for their research over the next five years. The funding is intended to provide promising young researchers with the best possible working conditions and to improve the compatibility of family and career.

The CIO Köln/Bonn is the only location in North Rhine-Westphalia that qualified for DKH funding. 

Prof. Dr. Nicolas Wernert, Dean Medical Faculty of the University of Bonn, lauded the opportunities the award will bring to cancer research and ImmunoSensation: "This approval will sustainably strengthen oncology research at both locations, especially in Bonn, through the research contributions of the ImmunoSensation cluster of excellence”.


Guest scientists from India and Thailand visit ImmunoSensation

July 02, 2018


Each year in Lindau, Nobel Laureates meet with the next-generation of scientists, with the aim of fostering the exchange of knowledge between different generations and nationalities. The junior scientist comprise of undergraduates, postgraduates and postdocs. The annual meetings focus on three natural science disciplines, and alternatingly feature the field of physiology and medicine, physics or chemistry and once in five years a joint meeting of the disciplines. For many years now, the DFG has invited participants from China, Thailand and India to tour top research institutions in Germany on the so-called “Post-Lindau Tour”. This year’s meeting was dedicated to the field of physiology and medicine and thus on the list of top ranking research institutions in this field was the Faculty of Medicine at the University of Bonn.


Career opportunity for PhD and Postdocs in the newly funded SFB/Transregio 237

June 25, 2018


About the Transregio
The SFB/TR is an interdisciplinary research network between the University of Bonn, the TU Dresden and the LMU Munich with participation of the University Marburg, the TU Munich and the MPI for Biochemistry Munich.
About the Science
Projects within the SFB/TR237 cover the diverse pathways involved in Nucleic Acid Immunity that have fundamental implications for human health and disease.
About the Candidates
The ideal candidates will be highly motivated and team oriented, with a strong interest in immunology and a first class academic degree in a life science related discipline.
PhD candidates: should have a Master's degree or equivalent for PhD positions, a strong background in molecular biomedicine, molecular biology, biochemistry or cell biology. 
Postdoctoral candidates: should have an outstanding scientific track record including publications in peer reviewed journals.


Open House Day at the Villa Hammerschmidt

June 24, 2018 - June 24, 2018


As part of the events to celebrate its 200 years anniversary, the University of Bonn featured varies institutions and departments during the Open House at the Villa Hammerschmidt on Sunday, June 24, 2018. The event was visited by more than 14,000 people.
The Cluster Coordination office (CCO) and Cluster scientists from the Institute of Medical Microbiology Immunology and Parasitology (IMMIP) represented ImmunoSensation program during this event in the Tent "Global Health".
IMMIP Director Prof. Achim Hörauf and his team of scientists introduced the visitors into microscopy of successful worm treatment of filariasis patients, a group of neglected tropical diseases commonly known as elephantiasis and river blindness. The staff demonstrated how adult filarial worms are sterilized and killed by targeting endosymbiotic Wolbachia bacteria with the antibiotic doxycycline.
The Cluster Coordination Office had a long line of curious participants who wanted to play the role of immune cells and find out if through their sense of touch, they could identify the foreign object.
The immune-sensing game and microscopy were popular among all age groups.
The highlight of the our tent was a short visit by Germany's Federal President Frank-Walter Steinmeier. Prof. Hörauf introduced the Federal President into the current research of the Excellence Cluster and participating institutions. Watch the video of this memorable moment here. 


Cluster Publication in Journal of Neuroscience by Prof. Beck

June 01, 2018


A new publication by our Cluster member Prof. Heinz Beck shows, why the worldwide leading medication against epilepsy might not be suitable for a lot of patients.
The new findings published in the Journal of Neuroscience could lead to better and more effective therapies against epilepsy. This is of high importance since every third patient is not responding to the prescripted drugs these days.


Transregio Nucleic Acid Immunity funded by DFG

May 21, 2018


The new Transregio 'Nucleic Acid Immunity' from the Unversity Bonn, TU Dresden and LMU Munich is funded by the DFG for a first round of 4 years from July 1st on.
Prof. Gunther Hartmann is the speaker of this consortium of researcher who will investigate the molecular mechanisms of recognizing foreign nucleic acids by our immune system.
This is of special importance since the malfunction of this system leads to various diseases such as chronic viral infections, inflammation and autoimmune disorders.
11 research groups of the medical faculty from the University Bonn are participating in this Transregio.


Ringvorlesung talks

May 17, 2018 - June 12, 2018


As part of the celebration of the 200 years anniversary of the University of Bonn, Excellence Cluster ImmunoSensation organized public lectures. These talks were held in German and were presented by Cluster scientists in a way that the general public could follow and understand.
The lectures were impressively visited and we got a lot of positive feedbacks from the members of the public who would like to have more of such very informative presentations.
ImmunoSensation would like to sincerely thank Prof. Kathrin Paeschke, Prof. Eva Kiermaier, Dr. Elvira mass, Prof. Eicke Latz, Prof. Gunther Hartmann, Prof. Joachim Schultze and Prof. Michael Heneka for taking their time to give this talks.
Some of the talks are available as videos and can be watched by clicking on the Surnames:


Night of Science- Wissenschaftsnacht

May 17, 2018 - May 18, 2018


Every alternate year in Bonn, Bonner Wissenschaftsnacht (Night of Science) is held at the Münsterplatz-Bonn. We at the Cluster of Excellence ImmunoSensation, joined other scientist from Bonn, Rhein-Sieg-Kreis and Kreis-Ahrweiler at the tent in Münsterplatz to contribute to the theme on Circulation. Using a torso from the Institute of Anatomy- University of Bonn and a chimpanzee skull from Museum König, cluster scientists explained the T-cell immune response invoked during HIV infection to members of the public. The chimpanzee skull was representative of the non-human primates that can be infected with a Lentivirus similar to HIV the SIV (Simian Immunodeficiency Virus). The scientist used microscopes to show immune cells in different organs using tissue sections mounted on slides.
We sincerely thank; Cluster members and scientists for their support, Bonner Wissenschaftsnacht for the opportunity to participate, Institute of Anatomy-University of Bonn for the torso, Museum König for the chimpanzee skull, the volunteers from Prof. Latz's group- Institute for Innate Immunity, Prof. Kolanus- LIMES institute, for the tissue section and Institute of Medical Microbiology Immunology and Parasitology for the Microscopes. 


Lamas and Alpacas as a tool for immunological research

May 16, 2018


Proteins are highly important for lots of processes in our body. To gain more knowledge about their function, researchers would like to modify or completey remove them from our body.
Our Cluster researcher Dr. Florian Schmidt, group leader of an Emmy Noether-Research group at the Institute of Innate Immunity is further developing a method for designing protein-blockers with the help of Alpacas and Lamas.
You can find the german press release here.
Dr. Florian I. Schmidt
Emmy Noether-Group Leader
Institute of Innate Immunity
University of Bonn
Tel. 0228/28751124


New DFG Statement of the replicability of research results

May 08, 2018


The German Research Council announced its new statement for the replicability of research results in the field of medicine and biomedicine.
You can find the german press release from the DFG website here.
The statement can be found on our homepage - although it is only in german.


Kinderuni - Do cells have eyes? Can cells see?

May 07, 2018 - May 07, 2018


Prof. Dagmar Wachten from the Institute of Innate Immunity, University of Bonn, gave an intriguing lecture to young enthusiastic 8-13 year olds, who were participants in the Kinderuni program. Do cells have eyes? (’’Können Zellen gucken’’) was the topic of her lecture, which stimulated the minds of the young participants, resulting in questions and discussions. Photos can be found on this link.


Day of Immunology 2018

May 05, 2018


Scientists from the ImmunoSensation Cluster of Excellence took time to share interesting, new and current research with members of the public at Bonn Marktplatz to mark the Day of Immunology. On that fine sunny spring Saturday, residents from Bonn and the surrounding visited the ImmunoSensation tent and asked questions related to immunology of the presented disciplines. To spice the day up, 5 public talks were held in 3 different locations, and attendees were not shy to ask the presenters questions, which was a confirmation that the talks were a success.
At the end of the day, cluster scientists and members of the public had a nice ImmunoSensational day. We sincerly thank the Bundesstadt Bonn- Economic Development Office for letting us on the Marktplatz.


Cluster publication in Nature Genetics

April 30, 2018


Cluster member Prof. Markus Nöthen and colleagues published with an international consortium 30 new gene loci that are connected with depression.
The recent publication was released in Nature Genetics and integrated the data of 135.000 patients and 344.000 healthy controls.
Find the german press release here.
Publication: Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression, Nature Genetics, DOI: 10.1038/s41588-018-0090-3


Ringvorlesung: Herausforderungen der biomedizinischen Forschung

April 05, 2018


The Cluster of Excellence ImmunoSensation is proud to share with you, that we organize a lecture series about challengens in the biomedical research field.
We invite you to join us on different dates from april 17 until june 12 in the Main Building of the University Bonn, Lecture Hall 1.
It starts 6.30 pm and you can bring your non-english speaking friends since the lectures are always in german. Afterwards there is time to ask questions.