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ImmunoSensation - the immune sensory system

Cluster Research paper in Gut published

June 21, 2017


Scientists of the University Hospitals in Bonn and Essen could show what drives one of the much-feared complications of gastrointestinal operations.
Scientists Prof. Christian Kurts from the Institute of Experimental Immunology Bonn, member of the Cluster of Excellence ImmunoSensation, and Prof. Daniel Engel from the Department of Immunodynamics Essen published their most recent findings in the Journal Gut.
They showed that bacteria are recognized by specialized immune cells in the gut, which can lead to a paralysis of the intestines. This is called post-operative ileus.
Find more information about the publication here.


New Newsletter released

June 14, 2017


Shortly before holiday season we gathered all important information throughout the last 6 months. Now you can find all the things that happened in the Cluster of Excellence ImmunoSensation in our newest edition of our Newsletter. Don't miss it and show your parents and loved ones in which exciting scientific area you are working in.
Enjoy reading it and we are happy to take suggestions for further topics that should be covered.
Find our newsletter edition 5 here and here.


Application open for a female PostDoc Scholarship until July 31

June 06, 2017


The University Bonn invites all female PostDocs to apply for the Annemarie Schimmel-Scholarship 2017.
It covers 2.300 Euro monthly for up to 12 months with the option of an extention of 6 more months. It is open for female PostDocs up to three years after they finished their PhD.
Find more information here:


Cluster member Prof. Hörauf elected chairman of DNTD Network

May 29, 2017


Cluster member Prof. Achim Hörauf, director of the Institute of Medical Microbiology, Immunology and Parasitoloy University Clinics Bonn, was elected chairman for the German Network to combat Neglected Tropical Diseases (DNTDs) May 18 in Berlin.
The German Network against neglected tropical diseases forms a national platform in Germany designed to heighten awareness of this group of diseases and raise the level of commitment in Germany to fighting them. The German network wishes to support the World Health Organization (WHO) in controlling, eliminating or even eradicating at least ten of the 18 neglected tropical diseases. 
Find here the german press release.


ImmunoSensation and HCM are looking for new Professors and PostDocs

May 16, 2017


The University of Bonn with its two Clusters of Excellence, the Hausdorff Center for Mathematics, and ImmunoSensation, intends to significantly strengthen the existing collaborations between these two clusters and to establish an internationally visible research group in the field of mathematical modeling in life and medical sciences. In this context, it invites applications for
three temporary Professorships (W2) for 5 years
three research positions (E13) for 3 years for Postdocs
find here more information how to apply.
Applcation deadline for the professorships are approaching.


Cannabis reverses ageing processes in the brain

May 09, 2017


Memory performance decreases with increasing age. Cannabis can reverse these ageing processes in the brain. This was shown in mice by scientists at the University of Bonn with their colleagues at The Hebrew University of Jerusalem (Israel). Old animals were able to regress to the state of two-month-old mice with a prolonged low-dose treatment with a cannabis active ingredient. This opens up new options, for instance, when it comes to treating dementia. The results are now presented in the journal Nature Medicine.
Prof. Andreas Zimmer and Prof. Joachim L. Schultze are both members of the Cluster of Excellence ImmunoSensation.
Publication: A chronic low dose of delta9-tetrahydrocannabinol (THC) restores cognitive function in old mice, Nature Medicine, DOI: 10.1038/nm.4311
Find the german press release here and the english press release here.


Day of Immunology 2017

May 08, 2017


The Day of Immunology was a huge success.
On Saturday, April 29, we celebrated this years International Day of Immunology with an exhibition of some of our research that's been conducted within the Cluster.
The focus of the exhibition was on widespread diseases such as Atherosclerosis, Alzheimer's or Malnutrition. Walk-in models of the brain, the mouth and an artery were not only playgrounds for kids but also informative and inspiring spots.
Thanks to all our researchers and the City of Bonn who contributed to this amazing event.
Find here our Info-Displays: Alzheimer's, Atherosclerosis, Tumor Vaccination, Influenza and Malnutrition.


Science Publication: Where do immune cells come from?

May 05, 2017


Congratulation to Cluster member Dr. Andreas Schlitzer, PD Dr. Marc Beyer and Prof. Dr. Joachim L. Schultze from the LIMES Institute Bonn. They recently published their newest findings about dendritic cell progenitors in Science.
Publication: Mapping the human DC lineage through the integration of high-dimensional techniques, Science, DOI: 10.1126/science.aag3009
Find the german press release here and the english press release here.


Cluster speaker Prof. Gunther Hartmann gives a public lecture

May 04, 2017


Cluster speaker and director of the Institute for Clinical Chemistry and Clinical Pharmacology at the University Hospital Bonn Prof. Gunther Hartmann gives a public lecture on May, 17 6pm.
The lecture will take place in the Old Town Hall Bonn (Althes Rathaus Bonn, Gobelinsaal) and the entrance is free.
The lecture is organized by the Adult Education Center of Bonn and is entitled:
Erbgut im Wettstreit mit Viren - wie unser Immunsystem die Gefahr meistet.


New Cluster Publication in Nature Immunology

May 03, 2017


Cluster member Prof. Joachim L. Schultze and his colleague Dr. Thomas Ulas, both from the LIMES Institute of the University of Bonn, published their finding in the highly ranked journal Nature Immunology.
They showed that babies are born with an immune system which has a reduced activity. That prevents the immune system to overreact after the babies are being born and come in contact with millions of pathogens and foreign substances.
The new findings can lead to the development for new therapies against a life-threatening sepsis which can occur in premature infants.
Publication: Thomas Ulas et al.: S100 alarmin-induced innate immune programming protects newborn infants from sepsis; Nature Immunology; DOI: 10.1038/ni.3745
Find the german press release here.


Girls' Day 2017

April 28, 2017


As last year we celebrated the Girls' Day in the Excellence Cluster ImmunoSensation by inviting 6 girls to one of our labs.
This year Dr. Annkristin Heine and her team showed them how to isolate DNA out of tomatoes.
You can find pictures of the day here.


New patent helps to boost immune system against cancer cells

April 27, 2017


Researchers at the ImmunoSensation cluster of excellence at the University of Bonn have managed to do what many scientists dream of: together with researchers from the USA, they have patented new molecules that allow the immune system to be directed against tumor cells. The license has already given the University of Bonn a first payment – and the scientists also gained a share. An exemplary success within the biomedical research landscape in Germany.
Cluster scientists Prof. Gunther Hartmann, Prof. Winfried Barchet and Dr. Thomas Zillinger were part of that ground-breaking research.
Please find the german press release here and the english press release here.


Young Scientists visit ImmunoSensation

March 29, 2017


Seven young scientists visited the ImmunoSensation Cluster of Excellence on March 31 in the context of the German juFORUM e.V.
Deutsches Jungforschernetzwerk - juFORUM e.V. is a network by and for young scientists and other people interested in STEM (science, technology, engineering and mathematics). It was established in 2000 by former participants of Jugend forscht, a German youth science competition.
They visited the central laboratory and the Institute for Experimental Immunology.
You can find more pictures on our picture site and an article about the success of the day here.


Cluster goes Charity 2017: Shoes for little hearts

March 23, 2017


With the help of our cluster members - Immuna and Immuno could deliver more than 7 big packages of shoes for Kinderherzen - Fördergemeinschaft Deutsche Kinderherzzentren e.V.!
Thank you all for your help.


New Publication by Cluster member Prof. Regina Betz

March 14, 2017


Cluster member Prof. Regina Betz from the Institute of Human Genetics published her recent findings in the Journal of Clinical Investigations.
Dowling-Degos disease is a hereditary pigmentation disorder that generally progresses harmlessly. However, some of those affected also develop severe skin inflammation. An international team of researchers under the leadership of the University of Bonn has now found a cause for this link. Their knowledge comes thanks to an animal that is known among aquarium owners for its characteristic pigmentation: the zebrafish.


ImmunoSensation participated in the University Science Rallye 2017

March 10, 2017


The Cluster of Excellence ImmunoSensation participated for the first time in the Science Rallye of the Rheinische Friedrich-Wilhelms-University of Bonn.
Here young scientist of the age between 13 and 17 can participate in a rallye around the campus in Bonn Poppelsdorf. With interesting stops at the mathematics or the geology department attending pupils get to know the University and its departments.
The Cluster of Excellence ImmunoSensation displyed with the group of Prof. Kolanus from the LIMES Institute a parcour. Here you could learn what the immune systems consists off, what the immune cells are doing and how the immune system distinguishes between various pathogens. We had a lot of fun participating and looking forward to next years Science Rallye.


Kinderuni - Finding the missing piece: How to develop drugs?

March 06, 2017


The Kinderuni from the Rheinische Friedrich-Wilhelms-University Bonn can lead to an official diploma, if the kids attend at least 10 lectures in one year.
Cluster member Prof. Matthias Geyer gave an introduction on 'How drugs are being developed?'. 
Again lots of children attended the lecture and challenged Matthias Geyer with lots of interesting questions afterwards.


TAKeOFF being funded by Federal Ministry of Education and Research

March 02, 2017


Cluster member Prof. Achim Hörauf and his lab are now funded by the Federal Ministry of Education and Research. Five german-african networks fighting infectious disases like malaria or dengue fiever were chosen. The network TAKeOFF is one of them.
Mainly in Africa and Asia, more than 200 million people are parasitised by filarial nematodes (roundworms), which cause the neglected tropical diseases lymphatic filariasis, loiasis and onchocerciasis. By establishing a Filarial Clinical Trial & Research Platform (F-CuRE), the TAKeOFF consortium aims to harmonise the procedure for clinical trials in filariasis. To improve treatment regimens for morbidity control of filarial and non-filarial lymphedema (podoconiosis), the partners will conduct multinational clinical trials in sub-Saharan Africa, thereby addressing patient needs as well as the science behind these diseases.
Find the german press release here.


Master student from Syria featured in german news

February 23, 2017


The Master student Mohammed Hajo working in the lab of Jasper van den Boorn in the Insitute of Clinical Chemistry and Clinical Pharmacology is featured in german news.
He is originally from Syria and came to germany in 2015. He conducts his master thesis in the field of immunotherapies for cancer and maybe wants to conduct a PhD afterwards.
Find the german article here.


New Cluster publication: How do T cells end up where they are needed?

February 20, 2017


A new cluster publication recently published in the European Journal of Immunology by cluster member Prof. Waldemar Kolanus from the LIMES (Life and Medical Sciences) Institue shows how T cells are directed to the places where they are needed the most.
Find the german press release here.