Cluster member Heneka publishes in Nature

December 21, 2017

Inflammatory proteins (called “ASC specks”, red) within the nucleus of an aggregate of Amyloid-beta peptides (blue). Furthermore, immune cells (green) are shown. Researchers of the DZNE and the University of Bonn report in “Nature” on the role of inflammatory mechanisms in Alzheimer’s disease. Image reconstruction of microscopy imaging data. (c) Dario Tejera/Uni Bonn

Prof. Dr. Michael Heneka, a senior researcher at the DZNE and Director of the Department of Neurodegenerative Diseases and Gerontopsychiatry at the University of Bonn. (c) Photo: UKB/UKOM

 

Another great publication completes this fantastic year 2017.

Cluster member Prof. Heneka from the German Center for Neurodegenerative Diseases (DZNE) and his colleagues could publish their findings in the well-known Journal Nature.

According to a study now published in the journal “Nature”, inflammatory mechanisms caused by the brain’s immune system drive the progression of Alzheimer’s disease. These findings, which rely on a series of laboratory experiments, provide new insights into pathogenetic mechanisms that are believed to hold potential for tackling Alzheimer’s before symptoms manifest. The researchers envision that one day this may lead to new ways of treatment. Further institutions both from Europe and the US also contributed to the current results.

Congratulations to this amazing achievement!

Publication: “Microglia-derived ASC specks cross-seed ß-amyloid in Alzheimer’s disease”, Carmen Venegas, Sathish Kumar et al., Nature (2017), DOI: 10.1038/nature25158

Find the german press release here and the english press release here.