ImmunoSensation - the immune sensory system

1. Successful treatment with interleukin-17A antagonists of generalized pustular psoriasis in patients without IL36RN mutations.
Wilsmann-Theis D, Schnell LM, Ralser-Isselstein V, Bieber T, Schön MP, Hüffmeier U, Mössner R
J Dermatol. 2018 Apr 14.
PMID: 29655177
2. Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus.
Stein K, Hieggelke L, Schneiker B, Lysson M, Stoffels B, Nuding S, Wehkamp J, Kikhney J, Moter A, Kalff JC, Wehner S
PLoS One. 2018 Apr 13.
PMID: 29652914
3. Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.
Pan WH, Sommer F, Falk-Paulsen M, Ulas T, Best P, Fazio A, Kachroo P, Luzius A, Jentzsch M, Rehman A, Müller F, Lengauer T, Walter J, Künzel S, Baines JF, Schreiber S, Franke A, Schultze JL, Bäckhed F, Rosenstiel P
Genome Med. 2018 Apr 13.
PMID: 29653584
4. Flow-mediated dilation, nitroglycerin-mediated dilation and their ratio predict successful renal denervation in mild resistant hypertension.
Steinmetz M, Nelles D, Weisser-Thomas J, Schaefer C, Nickenig G, Werner N
Clin Res Cardiol. 2018 Apr 11.
PMID: 29644413
5. Innate immune memory in the brain shapes neurological disease hallmarks.
Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ
Nature. 2018 Apr 11.
PMID: 29643512
6. Severe abnormal Heart Rate Turbulence Onset is associated with deterioration of liver cirrhosis.
Jansen C, Al-Kassou B, Lehmann J, Pohlmann A, Chang J, Praktiknjo M, Nickenig G, Strassburg CP, Schrickel JW, Andrié R, Linhart M, Trebicka J
PLoS One. 2018 Apr 10.
PMID: 29634776
7. Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.
Bickert A, Kern P, van Uelft M, Herresthal S, Ulas T, Gutbrod K, Breiden B, Degen J, Sandhoff K, Schultze JL, Dörmann P, Hartmann D, Bauer R, Willecke K
Biochim Biophys Acta. 2018 Apr 10.
PMID: 29653252
8. Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM, Harrison CJ, Moorman AV, Vora A, Roman E, Rachakonda S, Kinsey SE, Sheridan E, Thompson PD, Irving JA, Koehler R, Hoffmann P, Nöthen MM, Heilmann-Heimbach S, Jöckel KH, Easton DF, Pharaoh PDP, Dunning AM, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Greaves M, Zimmerman M, Bartram CR, Schrappe M, Stanulla M, Hemminki K, Houlston RS,
Nat Commun. 2018 Apr 9.
PMID: 29632299
9. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?
Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Roßner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L
Alzheimers Dement. 2018 Apr 6.
PMID: 29630865
10. Candida induces the expression of IL-36γ in human keratinocytes:Implications for a pathogen-driven exacerbation of psoriasis?
Braegelmann J, Braegelmann C, Bieber T, Wenzel J
J Eur Acad Dermatol Venereol. 2018 Apr 6.
PMID: 29633390
11. CCL17 blockade as a therapy for osteoarthritis pain and disease.
Lee MC, Saleh R, Achuthan A, Fleetwood AJ, Förster I, Hamilton JA, Cook AD
Arthritis Res Ther. 2018 Apr 5.
PMID: 29622035
12. Antigen-specific Helios, Neuropilin-1Tregs induce apoptosis of autoreactive B cells via PD-L1.
Gotot J, Dhana E, Yagita H, Kaiser R, Ludwig-Portugall I, Kurts C
Immunol Cell Biol. 2018 Apr 4.
PMID: 29617057
13. Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome.
Bonfiglio F, Zheng T, Garcia-Etxebarria K, Hadizadeh F, Bujanda L, Bresso F, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, Simren M, Walter S, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Portincasa P, Bellini M, Barbara G, Latiano A, Hübenthal M, Thijs V, Netea MG, Jonkers D, Chang L, Mayer EA, Wouters MM, Boeckxstaens G, Camilleri M, Franke A, Zhernakova A, D'Amato M
Gastroenterology. 2018 Apr 4.
PMID: 29626450
14. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation.
Vogl T, Stratis A, Wixler V, Völler T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Fröhling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schäfers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, König S, Pap T, Roth J
J Clin Invest. 2018 Apr 3.
PMID: 29611822
15. Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study.
Bergheim J, Semaan A, Gevensleben H, Groening S, Knoblich A, Dietrich J, Weber J, Kalff JC, Bootz F, Kristiansen G, Dietrich D
Br J Cancer. 2018 Apr 3.
PMID: 29610456
16. Tissue metabolic changes drive cytokine responses to Mycobacterium tuberculosis.
Lachmandas E, Rios-Miguel AB, Koeken VACM, van der Pasch E, Kumar V, Matzaraki V, Li Y, Oosting M, Joosten LAB, Notebaart RA, Noursadeghi M, Netea MG, van Crevel R, Pollara G
J Infect Dis. 2018 Apr 3.
PMID: 29618104
17. Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial Infarction.
Loyer X, Zlatanova I, Devue C, Yin M, Howangyin KY, Klaihmon P, Guerin CL, Kheloufi M, Vilar J, Zannis K, Fleischmann BK, Hwang DW, Park J, Lee H, Menasche P, Silvestre JS, Boulanger CM
Circ Res. 2018 Mar 28.
PMID: 29592957
18. VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites.
Czogalla KJ, Liphardt K, Höning K, Hornung V, Biswas A, Watzka M, Oldenburg J
Blood Adv. 2018 Mar 27.
PMID: 29581108
19. Circulating microbiome in blood of different circulatory compartments.
Schierwagen R, Alvarez-Silva C, Madsen MSA, Kolbe CC, Meyer C, Thomas D, Uschner FE, Magdaleno F, Jansen C, Pohlmann A, Praktiknjo M, Hischebeth GT, Molitor E, Latz E, Lelouvier B, Trebicka J, Arumugam M
Gut. 2018 Mar 26.
PMID: 29581241
20. Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome.
Smits LP, Kootte RS, Levin E, Prodan A, Fuentes S, Zoetendal EG, Wang Z, Levison BS, Cleophas MCP, Kemper EM, Dallinga-Thie GM, Groen AK, Joosten LAB, Netea MG, Stroes ESG, de Vos WM, Hazen SL, Nieuwdorp M
J Am Heart Assoc. 2018 Mar 26.
PMID: 29581220
21. High rate of persistent iatrogenic atrial septal defect after single transseptal puncture for cryoballoon pulmonary vein isolation.
Linhart M, Werner JT, Stöckigt F, Kohlmann AT, Lodde PC, Linneborn LPT, Beiert T, Hammerstingl C, Borràs R, Nickenig G, Andrié RP, Schrickel JW
J Interv Card Electrophysiol. 2018 Mar 24.
PMID: 29574595
22. Towards Precision Medicine in Sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases.
Rello J, van Engelen TSR, Alp E, Calandra T, Cattoir V, Kern WV, Netea MG, Nseir S, Opal SM, van de Veerdonk FL, Wilcox MH, Wiersinga WJ
Clin Microbiol Infect. 2018 Mar 23.
PMID: 29581049
23. Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer.
Bano D, Prehn JHM
EBioMedicine. 2018 Mar 23.
PMID: 29605508
24. Management of sudden cardiac death in cardiac sarcoidosis using the wearable cardioverter defibrillator.
Skowasch D, Ringquist S, Nickenig G, Andrié R
PLoS One. 2018 Mar 22.
PMID: 29566033
25. TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.
Cook AD, Lee MC, Saleh R, Khiew HW, Christensen AD, Achuthan A, Fleetwood AJ, Lacey DC, Smith JE, Förster I, Hamilton JA
JCI Insight. 2018 Mar 22.
PMID: 29563337
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