ImmunoSensation - the immune sensory system

1. Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder.
Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S
Transl Psychiatry. 2018 Oct 8.
PMID: 30297702
2. Bleeding events and safety outcomes in persons with haemophilia A with inhibitors: A prospective, multi-centre, non-interventional study.
Mahlangu J, Oldenburg J, Callaghan MU, Shima M, Santagostino E, Moore M, Recht M, Garcia C, Yang R, Lehle M, Macharia H, Asikanius E, Levy GG, Kruse-Jarres R
Haemophilia. 2018 Oct 8.
PMID: 30295389
3. The importance of inhibitor eradication in clinically complicated hemophilia A patients.
Oldenburg J, Young G, Santagostino E, Escuriola Ettingshausen C
Expert Rev Hematol. 2018 Oct 4.
PMID: 30286680
4. Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis.
Chhatbar C, Detje CN, Grabski E, Borst K, Spanier J, Ghita L, Elliott DA, Jordão MJC, Mueller N, Sutton J, Prajeeth CK, Gudi V, Klein MA, Prinz M, Bradke F, Stangel M, Kalinke U
Cell Rep. 2018 Oct 2.
PMID: 30282022
5. A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O
Nat Commun. 2018 Oct 2.
PMID: 30279449
6. The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG
Cell Metab. 2018 Oct 1.
PMID: 30293776
7. A Novel iRFP-Incorporated in vivo Murine Atherosclerosis Imaging System.
Kulathunga K, Hamada M, Hiraishi Y, Otake M, Tran MTN, Cheng O, Tanaka J, Sakasai T, Sakaguchi S, Sugiyama Y, Fleischmann BK, Takahashi S, Miwa Y
Sci Rep. 2018 Sep 28.
PMID: 30266983
8. Current Therapeutic Options for Pancreatic Ductal Adenocarcinoma.
Bisht S, Brossart P, Feldmann G
Oncol Res Treat. 2018 Sep 28.
PMID: 30286472
9. 'Diseases Desperate Grown by Desperate Appliance Are Relieved, or Not at all' - Towards Finding a Cure for Pancreatic Cancer, Where Do We Stand Today?
Feldmann G, Brossart P, Maitra A
Oncol Res Treat. 2018 Sep 28.
PMID: 30286471
10. Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G.
van Splunter M, van Osch TLJ, Brugman S, Savelkoul HFJ, Joosten LAB, Netea MG, van Neerven RJJ
Nutrients. 2018 Sep 27.
PMID: 30262772
11. NLRP3 inflammasome activation in inflammaging.
Latz E, Duewell P
Semin Immunol. 2018 Sep 26.
PMID: 30268598
12. Intestinal Inflammation and Dysregulated Immunity in Patients with Inherited Caspase-8 Deficiency.
Lehle AS, Farin HF, Marquardt B, Michels BE, Magg T, Li Y, Liu Y, Ghalandary M, Lammens K, Hollizeck S, Rohlfs M, Hauck F, Conca R, Walz C, Weiss B, Lev A, Simon AJ, Groß O, Gaidt MM, Hornung V, Clevers H, Yazbeck N, Hanna-Wakim R, Shouval DS, Warner N, Somech R, Muise AM, Snapper SS, Bufler P, Koletzko S, Klein C, Kotlarz D
Gastroenterology. 2018 Sep 26.
PMID: 30267714
13. ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A, Jentzsch M, Falk-Paulsen M, Stengel ST, Welz L, Schwarzer R, Rabe B, Barchet W, Krautwald S, Hartmann G, Pasparakis M, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P
J Exp Med. 2018 Sep 25.
PMID: 30254094
14. First Case of Laparoscopic Mini-Gastric Bypass for the Treatment of Morbid Obesity in Severe Haemophilia A.
Plamper A, Goldmann G, Lingohr P, Horneff S, Dohmen J, Oldenburg J, Rheinwalt KP
Hamostaseologie. 2018 Sep 24.
PMID: 30248701
15. Once-weekly prophylaxis with 40 IU/kg nonacog beta pegol (N9-GP) achieves trough levels of >15% in patients with haemophilia B: Pooled data from the paradigm™ trials.
Oldenburg J, Carcao M, Lentz SR, Mahlangu J, Mancuso ME, Matsushita T, Négrier C, Clausen WHO, Ehrenforth S, Young G
Haemophilia. 2018 Sep 24.
PMID: 30248217
16. Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.
Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, , , Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J
Nat Genet. 2018 Sep 24.
PMID: 30250126
17. Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.
Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kuebler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT
Int J Cardiol. 2018 Sep 20.
PMID: 30314839
18. Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity towards autologous melanoma cells.
Daßler-Plenker J, Paschen A, Putschli B, Rattay S, Schmitz S, Goldeck M, Bartok E, Hartmann G, Coch C
Int J Cancer. 2018 Sep 19.
PMID: 30230526
19. Induction of innate immune memory: the role of cellular metabolism.
Domínguez-Andrés J, Joosten LA, Netea MG
Curr Opin Immunol. 2018 Sep 18.
PMID: 30240964
20. Sonic hedgehog signaling regulates the mammalian cardiac regenerative response.
Kawagishi H, Xiong J, Rovira II, Pan H, Yan Y, Fleischmann BK, Yamada M, Finkel T
J Mol Cell Cardiol. 2018 Sep 17.
PMID: 30236923
21. Chronic nicotine administration restores brain region specific up-regulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia.
Zanos P, Keyworth H, Georgiou P, Kitchen I, Zimmer A, Bailey A
Eur J Neurosci. 2018 Sep 15.
PMID: 30218618
22. Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.
Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G, Holroyd A, Johnson DC, Li N, Orlando G, Law PJ, Ali M, Chen B, Mitchell JS, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Bandapalli OR, Einsele H, Gregory WA, Gullberg U, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Johnsson E, Kristinsson SY, Mellqvist UH, Nahi H, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Thomsen H, Turesson I, Vangsted A, Andersen NF, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Goldschmidt H, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Hemminki K, Nilsson B, Houlston RS,
Nat Commun. 2018 Sep 13.
PMID: 30213928
23. The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.
Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP
Cell Host Microbe. 2018 Sep 12.
PMID: 30212649
24. The chemokine receptor CX3CR1 reduces renal injury in mice with angiotensin II induced hypertension.
Ahadzadeh E, Rosendahl A, Czesla D, Steffens P, Prüßner L, Meyer-Schwesinger C, Wanner N, Paust HJ, Huber TB, Stahl RA, Wiech T, Kurts C, Seniuk A, Ehmke H, Wenzel UO
Am J Physiol Renal Physiol. 2018 Sep 12.
PMID: 30207169
25. Be aware, innate immune cells remember.
Riksen NP, Netea MG
Aging (Albany NY). 2018 Sep 12.
PMID: 30215600
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