Steering committee-member, Member
Life & Medical Sciences Institute (LIMES)
University of Bonn
Our aim is to identify new key regulators and genetic networks which control metabolism and cell and organ physiology. In particular, we elucidate the metabolism – innate immunity – gut microbiome axis, we investigate cellular (sphingo)lipid metabolism and body fat regulation, we study peroxisome and lysosome biogenesis and metabolic disorders (e.g. lipid storage diseases or neurodegeneration), and we analyse new regulators of cell-to-cell communication and tissue physiology. We use the fruit fly Drosophila, the mouse and zebra fish as genetic model organisms for our studies.