Steering committee-member, Member
Life & Medical Sciences Institute (LIMES)
University of Bonn
Prof. Kolanus and his group are interested in intracellular signal transduction events which control leukocyte adhesion, migration, and effector functions. The main emphasis of their current research activities lies in elucidating the role of integrin adhesion receptors and the cytoskeleton in the functional adaptation of leukocyte motility to specific microenvironments, some of which include force-dependent slow migration of immune cells on and across barriers, versus force-independent, fast migration in the interstitium.