ImmunoSensation - the immune sensory system

Singleton-Merten Syndrome-like Skeletal Abnormalities and MDA5

September 01, 2019

 

Singleton-Merten Syndrome-like Skeletal Abnormalities in Mice with Constitutively Activated MDA5Singleton-Merten syndrome (SMS) is a rare multisystem disorder characterized by systemic interferon signature, dental dysplasia, aortic calcification, skeletal abnormalities, and glaucoma, and

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Immune memory characteristics of innate lymphoid cells

June 23, 2019

 

Immune memory characteristics of innate lymphoid cells - ReviewImmunological memory is an evolutionally acquired trait that allows a more robust response of an organism to re-infection. Two types of immune memory have been characterized: adaptive immune memory that is antigen-specific and is

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Regulation of Innate Immune Responses by Platelets

June 11, 2019

 

Platelets have been extensively studied in the context of coagulation and their hemostatic imbalance can lead to conditions as atherosclerotic plaques and thrombosis. Nevertheless, the knowledge regarding the regulation of immune cell types by platelets has been growing exponentially in the past

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The helicase DHX36 resolves G-quadruplex structures and supports stress response

June 01, 2019

 

The helicase DHX36 resolves G-quadruplex structures and supports stress response

DNA and RNA G-quadruplex structures are thermodynamically very stable arrangements of four nucleic acid strands, in which the guanines interact via Hoogsteen base pairing. It has been shown that

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Tumor microenvironment of Pancreatic Cancer

March 27, 2019

 

Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells While studying B cells in pancreatic cancer, we noticed an important discrepancy between human data, which suggest B cells contribute

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