Seminar by Dr. Markus Hafner (NIH, Bethesda (Maryland) - USA)

June 17, 2019 - May 17, 2019


Dr. Markus Hafner
National Institute of Health
Bethesda (Maryland) - USA

Integrative Analysis of RNA Binding Protein Targets and Funtion

Date and Time
Monday, June 17, 2019 at 11:30 a.m (11:30 Hrs)

Lecture hall (basement floor)
Biomedizinisches Zentrum (BMZ), Venusberg

Prof. Dr. Katrin Paeschke



Dr. Markus Hafner an Earl Stadtman Tenure-Track Investigator at the National Institutes of Health in Bethesda, MD. His RNA Molecular Biology Group (RMBG) studies the impact of RNA binding proteins (RBPs) on posttranscriptional gene regulation (PTGR). PTGR summarizes various processes acting upon coding and non-coding RNA and includes RNA maturation, ribonucleoprotein (RNP) assembly, transport, translation, and turnover. The recent introduction of large-scale quantitative methods, such as next-generation sequencing (NGS) and modern mass spectrometry (MS), allows for the first time determination of the functional impact of RBPs on a systems-wide level and has sparked a renewed interest in the systematic characterization of PTGR processes. Members of the RMBG focus on elucidating the function and molecular mechanisms of RNA binding proteins involved in RNA transport, RNA stability and turnover, and RNA translation.