2 PhD Positions (65%), w/m/d on Metabolic Impact on the Immune System
Officer w/m/d (100%) for Public Relation and Outreach
The University Hospital Bonn is a maximum care facility with a regular capacity of 1.300 beds. Our current staff of more than 8.000 performs assigned duties in research, teaching and medical treatment, including the use of advanced medical technologies, and public health care services at the highest possible level. Interested applicants will be offered a wide range of employment opportunities in a variety of fields.
The Cluster of Excellence ImmunoSensation2 is inviting applications for
a PhD student position (m/f/d) (65%)
at the Bonn Graduate School of Immunosciences and Infection. The position is initially limited to three years with the possibility of extension.
ImmunoSensation2 is a Cluster of Excellence funded by Germany's ExcellenceStrategy at the University of Bonn. Participating scientists are dedicated toinvestigating immunity beyond the boundaries of classical immunology. In a joint effort, immunologists, neuro-biologists, systems biologists and mathematicians of theUniversity of Bonn and the German Center for Neurodegenerative Diseases (DZNE) of the Helmholtz Association aim to connect the status of the immunesystem, the metabolism and the nervous system to disease states. ImmunoSensation2 is embedded into the outstanding research environment of theUniversity of Bonn, the University Hospital and the DZNE. Furthermore, ImmunoSensation2 is internationally connected and maintains researchpartnerships with Australia (Melbourne University), Japan (Osaka University,Waseda University, Kyoto University) and the Netherlands (Radboud University,Nijmegen). Students will have the opportunity to receive additional financial support to participate in an official student exchange program (3 to 6 months) with selected principal investigators at these partner universities.
PhD students will be admitted to the Bonn International Graduate School Immunosciences and Infection. In this structured PhD program, students gain experience with state-of-the-art technologies and become part of a vibrant scientific network and an internationally competitive scientific training program.
The ideal candidate will be highly motivated and team-oriented with a strong interest in immunology, a first-class academic degree in a life science-related discipline (Master's degree or equivalent), a strong background in molecular biomedicine, molecular biology, biochemistry or cell biology and enthusiasm for working in theh ighly-competitive field of innate immunity research. Candidates should have strong communicative skills (fluent spoken and written English) since these are necessary for work in an international research landscape.
- The salary will be according to the German salary scale TV-L (EG 13)
- A "Jobticket" (subsidized public transport) is available
- There is also a possibility to use the day care center
- Supplementary benefits in the public sector (pension plan according to VBL)
The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. If therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status areparticularly welcome.
Applicants should send their application in a single pdf file (max. 5 MB) including motivation letter, CV, scanned academic degrees, list of publications and the contact details of two references. In your application, please indicate your preferred scientific project. The successful candidate will begin on July 1, 2021 or later.
Please send your application by email using the reference number 768_2020 until May 2nd, 2021 to Prof. Dr. Dirk Baumjohann University Hospital Bonn Medical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology Venusberg-Campus 153127 Bonn
Research in the group of Prof. Dr. Dirk Baumjohann at the Medical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology focuses on T helper cells, which coordinate cellular and antibody-mediated immune responses to a variety of pathogens. While several distinct T helper cell subsets have been described in the past, new research indicates that T helper cell differentiation is characterized by a considerable degree of flexibility and plasticity. We have a long-standing interest in T follicular helper (Tfh) cells, which represent the prototypic CD4+ T cell subset that provides help to B cells for efficient antibody responses. They may also contribute to cellular adaptive immunity, but the pathways remain largely unexplored. For this project, we seek a highly motivated candidate that will combine cellular and molecular immunology techniques with in vivo disease models, patient-derived samples, and single-cell approaches such as scRNA-seq and spatial profiling to dissect the mechanisms of Tfh and Tfh-like cells at the crossroads of immunity and autoimmunity.Previous hands-on experience in immunological techniques such as multidimensional flow cytometry and in vivo models is desired. Experience in human immunology or in conducting and analyzing scRNA-seq experiments is a plus. Good communication skills and fluency in English are essential.