ImmunoSensation - the immune sensory system

forsch Uni-Bonn Features 3 Cluster Scientist in the Summer 2018 Edition


July 16, 2018

 

The forsch magazine is a publication of the University of Bonn featuring interesting and top ongoing research in various disciplines at the University. 
The 2018 summer edition featured articles from 3 cluster scientist:
Dr. Florian Schmidt on his Nanobodies research and their generation using Alpacas (pg. 22), Prof. Dr. Heinz Beck research on new Epilepsy medication (pg. 28) and Prof. Dr. Markus Nöthen research together with the International Psychiatric Genomics Consortium on genes connected to depression  (pg 32)
Online copies are available available both as soft and hardcopies,Link to forsch

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10 Million Euros for Young Cancer Researchers


July 05, 2018

 

The Centre for Integrated Oncology (CIO) Köln/Bonn receives one of the five new " Mildred-Scheel-Nachwuchszentren" with which the German Cancer Aid (DKH) aims to keep cancer research in Germany fit for the future. CIO Köln/ Bonn will hence receive two million euros per year for five years, this money will be available to the young cancer scientists for their research over the next five years. The funding is intended to provide promising young researchers with the best possible working conditions and to improve the compatibility of family and career.

The CIO Köln/Bonn is the only location in North Rhine-Westphalia that qualified for DKH funding. 

Prof. Dr. Nicolas Wernert, Dean Medical Faculty of the University of Bonn, lauded the opportunities the award will bring to cancer research and ImmunoSensation: "This approval will sustainably strengthen oncology research at both locations, especially in Bonn, through the research contributions of the ImmunoSensation cluster of excellence”.

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Guest scientists from India and Thailand visit ImmunoSensation


July 02, 2018

 

Each year in Lindau, Nobel Laureates meet with the next-generation of scientists, with the aim of fostering the exchange of knowledge between different generations and nationalities. The junior scientist comprise of undergraduates, postgraduates and postdocs. The annual meetings focus on three natural science disciplines, and alternatingly feature the field of physiology and medicine, physics or chemistry and once in five years a joint meeting of the disciplines. For many years now, the DFG has invited participants from China, Thailand and India to tour top research institutions in Germany on the so-called “Post-Lindau Tour”. This year’s meeting was dedicated to the field of physiology and medicine and thus on the list of top ranking research institutions in this field was the Faculty of Medicine at the University of Bonn.

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Career opportunity for PhD and Postdocs in the newly funded SFB/Transregio 237


June 25, 2018

 

About the Transregio
The SFB/TR is an interdisciplinary research network between the University of Bonn, the TU Dresden and the LMU Munich with participation of the University Marburg, the TU Munich and the MPI for Biochemistry Munich.
About the Science
Projects within the SFB/TR237 cover the diverse pathways involved in Nucleic Acid Immunity that have fundamental implications for human health and disease.
About the Candidates
The ideal candidates will be highly motivated and team oriented, with a strong interest in immunology and a first class academic degree in a life science related discipline.
PhD candidates: should have a Master's degree or equivalent for PhD positions, a strong background in molecular biomedicine, molecular biology, biochemistry or cell biology. 
Postdoctoral candidates: should have an outstanding scientific track record including publications in peer reviewed journals.

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Open House Day at the Villa Hammerschmidt


June 24, 2018 - June 24, 2018

 

As part of the events to celebrate its 200 years anniversary, the University of Bonn featured varies institutions and departments during the Open House at the Villa Hammerschmidt on Sunday, June 24, 2018. The event was visited by more than 14,000 people.
The Cluster Coordination office (CCO) and Cluster scientists from the Institute of Medical Microbiology Immunology and Parasitology (IMMIP) represented ImmunoSensation program during this event in the Tent "Global Health".
IMMIP Director Prof. Achim Hörauf and his team of scientists introduced the visitors into microscopy of successful worm treatment of filariasis patients, a group of neglected tropical diseases commonly known as elephantiasis and river blindness. The staff demonstrated how adult filarial worms are sterilized and killed by targeting endosymbiotic Wolbachia bacteria with the antibiotic doxycycline.
The Cluster Coordination Office had a long line of curious participants who wanted to play the role of immune cells and find out if through their sense of touch, they could identify the foreign object.
The immune-sensing game and microscopy were popular among all age groups.
The highlight of the our tent was a short visit by Germany's Federal President Frank-Walter Steinmeier. Prof. Hörauf introduced the Federal President into the current research of the Excellence Cluster and participating institutions. Watch the video of this memorable moment here. 

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Cluster Publication in Journal of Neuroscience by Prof. Beck


June 01, 2018

 

A new publication by our Cluster member Prof. Heinz Beck shows, why the worldwide leading medication against epilepsy might not be suitable for a lot of patients.
The new findings published in the Journal of Neuroscience could lead to better and more effective therapies against epilepsy. This is of high importance since every third patient is not responding to the prescripted drugs these days.

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Transregio Nucleic Acid Immunity funded by DFG


May 21, 2018

 

The new Transregio 'Nucleic Acid Immunity' from the Unversity Bonn, TU Dresden and LMU Munich is funded by the DFG for a first round of 4 years from July 1st on.
Prof. Gunther Hartmann is the speaker of this consortium of researcher who will investigate the molecular mechanisms of recognizing foreign nucleic acids by our immune system.
This is of special importance since the malfunction of this system leads to various diseases such as chronic viral infections, inflammation and autoimmune disorders.
11 research groups of the medical faculty from the University Bonn are participating in this Transregio.

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Ringvorlesung talks


May 17, 2018 - June 12, 2018

 

As part of the celebration of the 200 years anniversary of the University of Bonn, Excellence Cluster ImmunoSensation organized public lectures. These talks were held in German and were presented by Cluster scientists in a way that the general public could follow and understand.
The lectures were impressively visited and we got a lot of positive feedbacks from the members of the public who would like to have more of such very informative presentations.
ImmunoSensation would like to sincerely thank Prof. Kathrin Paeschke, Prof. Eva Kiermaier, Dr. Elvira mass, Prof. Eicke Latz, Prof. Gunther Hartmann, Prof. Joachim Schultze and Prof. Michael Heneka for taking their time to give this talks.
Some of the talks are available as videos and can be watched by clicking on the Surnames:

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Night of Science- Wissenschaftsnacht


May 17, 2018 - May 18, 2018

 

Every alternate year in Bonn, Bonner Wissenschaftsnacht (Night of Science) is held at the Münsterplatz-Bonn. We at the Cluster of Excellence ImmunoSensation, joined other scientist from Bonn, Rhein-Sieg-Kreis and Kreis-Ahrweiler at the tent in Münsterplatz to contribute to the theme on Circulation. Using a torso from the Institute of Anatomy- University of Bonn and a chimpanzee skull from Museum König, cluster scientists explained the T-cell immune response invoked during HIV infection to members of the public. The chimpanzee skull was representative of the non-human primates that can be infected with a Lentivirus similar to HIV the SIV (Simian Immunodeficiency Virus). The scientist used microscopes to show immune cells in different organs using tissue sections mounted on slides.
We sincerely thank; Cluster members and scientists for their support, Bonner Wissenschaftsnacht for the opportunity to participate, Institute of Anatomy-University of Bonn for the torso, Museum König for the chimpanzee skull, the volunteers from Prof. Latz's group- Institute for Innate Immunity, Prof. Kolanus- LIMES institute, for the tissue section and Institute of Medical Microbiology Immunology and Parasitology for the Microscopes. 

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Lamas and Alpacas as a tool for immunological research


May 16, 2018

 

Proteins are highly important for lots of processes in our body. To gain more knowledge about their function, researchers would like to modify or completey remove them from our body.
Our Cluster researcher Dr. Florian Schmidt, group leader of an Emmy Noether-Research group at the Institute of Innate Immunity is further developing a method for designing protein-blockers with the help of Alpacas and Lamas.
You can find the german press release here.
Contact:
Dr. Florian I. Schmidt
Emmy Noether-Group Leader
Institute of Innate Immunity
University of Bonn
Tel. 0228/28751124
E-Mail: fschmidt@uni-bonn.de

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New DFG Statement of the replicability of research results


May 08, 2018

 

The German Research Council announced its new statement for the replicability of research results in the field of medicine and biomedicine.
You can find the german press release from the DFG website here.
The statement can be found on our homepage - although it is only in german.
http://www.immunosensation.de/press_media/links_downloads.html

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Kinderuni - Do cells have eyes? Can cells see?


May 07, 2018 - May 07, 2018

 

Prof. Dagmar Wachten from the Institute of Innate Immunity, University of Bonn, gave an intriguing lecture to young enthusiastic 8-13 year olds, who were participants in the Kinderuni program. Do cells have eyes? (’’Können Zellen gucken’’) was the topic of her lecture, which stimulated the minds of the young participants, resulting in questions and discussions. Photos can be found on this link.

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Day of Immunology 2018


May 05, 2018

 

Scientists from the ImmunoSensation Cluster of Excellence took time to share interesting, new and current research with members of the public at Bonn Marktplatz to mark the Day of Immunology. On that fine sunny spring Saturday, residents from Bonn and the surrounding visited the ImmunoSensation tent and asked questions related to immunology of the presented disciplines. To spice the day up, 5 public talks were held in 3 different locations, and attendees were not shy to ask the presenters questions, which was a confirmation that the talks were a success.
At the end of the day, cluster scientists and members of the public had a nice ImmunoSensational day. We sincerly thank the Bundesstadt Bonn- Economic Development Office for letting us on the Marktplatz.

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Cluster publication in Nature Genetics


April 30, 2018

 

Cluster member Prof. Markus Nöthen and colleagues published with an international consortium 30 new gene loci that are connected with depression.
The recent publication was released in Nature Genetics and integrated the data of 135.000 patients and 344.000 healthy controls.
Find the german press release here.
Publication: Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression, Nature Genetics, DOI: 10.1038/s41588-018-0090-3

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Ringvorlesung: Herausforderungen der biomedizinischen Forschung


April 05, 2018

 

The Cluster of Excellence ImmunoSensation is proud to share with you, that we organize a lecture series about challengens in the biomedical research field.
We invite you to join us on different dates from april 17 until june 12 in the Main Building of the University Bonn, Lecture Hall 1.
It starts 6.30 pm and you can bring your non-english speaking friends since the lectures are always in german. Afterwards there is time to ask questions.

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New member of the CCO Team


April 04, 2018

 

We are happy to announce that we have a new colleague in the Cluster Coordination Office.
Dr. Alexandra Krämer will be in charge for the IITB support within the CCO.
Do not hesitate to get in contact with Dr. Alexandra Krämer if you need advice regarding the IITB program.
You can contact her via alexandra.kraemer@uni-bonn.de or 0228 287 51182.
Welcome on board Alexandra.
Your CCO Team

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New competence network 'West German Genome Center'


March 19, 2018

 

The 'West German Genome Center' (WGGC) is a new initiative of the University of Bonn, University of Cologne and the Heinrich-Heine-University Düsseldorf. 
This new competence network is being funded with 5.3 Million Euro for three years by the German Research Foundation. It is the first infrastructure facility for the Areas of Bioinformatics, Genomics and High Throughput Computing.
Find the german press release here.

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Seminars by Next Generation Sequencing Core Facility


March 14, 2018

 

Dear Cluster member and Cluster scientist,

The Next Generation Sequencing (NGS) Core Facility invites you to two technical seminars: 

Topic: Chromium Single Cell 3¹ v2 - Application and protocol overview 

Date and time: Thursday, March 22, 2018 from 9:00 am to 11:00 am 

Location: Life & Brain, seminar room 


							
Topic: Theory refresher and software overview - Cell Ranger - Loupe Cell Browser 

Date and time: Friday, March 23, 2018 from 1:00 pm to 3:00 pm 

Location: Life & Brain, seminar room 

The seminars will be held by the company 10X Genomics. No registration! 

For more information, please contact Dr. rer. nat. André Heimbach (heimbach@uni-bonn.de), Head of NGS Core Facility.

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Roofing ceremony for new Cluster building


March 09, 2018

 

The roofing ceremony for our new cluster building - BMZ II - took place this Wednesday.
The BMZ II will host lab and office space for basic research in the field of immunology and infectiology. Also translational and clinical research areas can be found on the 4500 square meter. If everything goes as planned, the building will be opened in the 2nd quarter of 2019.
You can read here the german press release.

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IITB Students' Network Meeting


March 01, 2018

 

Speaker
Most recent scientific highlights within the Cluster of Excellence ImmunoSensation
Invited scientists of different career levels in a round table discussion about job
perspectives in science
Date & Time
Monday, March 12 2018, 2 pm (1pm until 5 pm)
Location
Haus Venusberg
Haager Weg 28-30, 53127 Bonn
Find the program here.
To register, use our online registration tool: http://community.ukb.uni-bonn.de/conftool

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We were a part of the Science Rallye Bonn


February 26, 2018

 

We took part in the Science Rallye of the University Bonn and teamed up with the LIMES Institut.
Together with the group of Prof. Günter Mayer (http://www.mayerlab.de/) we let the participants investigate in a case of murder - of course only a fictional one.
Have a look at the video here.
The next Science Rallye will take place February 9th, 2019 and we will for sure be a part again.

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Western Diet enhances Inflammation - Cell Publication


January 12, 2018

 

The immune system reacts similarly to a high fat and high calorie diet as to a bacterial infection. This is shown by a recent study led by the Cluster member Prof. Dr. Eicke Latz, who is director of the Institute of Innate Immunity Bonn.
Particularly disturbing: Unhealthy food seems to make the body’s defenses more aggressive in the long term. Even long after switching to a healthy diet, inflammation towards innate immune stimulation is more pronounced. These long-term changes may be involved in the development of arteriosclerosis and diabetes, diseases linked to Western diet consumption. The results will be published in the journal ‘Cell’.
“Genomic studies did, in fact, show that the Western diet had activated a large number of genes in the progenitor cells. The genes affected included those responsible for proliferation and maturation“, explains cluster member Prof. Dr. Joachim Schultze from the Life & Medical Sciences Institute (LIMES) and the German Center for Neurodegenerative Diseases (DZNE).
Publication: Anette Christ, Patrick Günther, Mario A.R. Lauterbach , Peter Duewell, Debjani Biswas, Karin Pelka, Claus J. Scholz, Marije Oosting, Kristian Haendler, Kevin Baßler, Kathrin Klee, Jonas Schulte-Schrepping, Thomas Ulas, Simone J.C.F.M. Moorlag, Vinod Kumar, Min Hi Park, Leo A.B. Joosten, Laszlo A. Groh, Niels P. Riksen, Terje Espevik, Andreas Schlitzer, Yang Li, Michael L. Fitzgerald, Mihai G. Netea, Joachim L. Schultze und Eicke Latz: Western diet triggers NLRP3-dependent innate immune reprograming; Cell, 11.1.2018, DOI: 10.1016/j.cell.2017.12.013
Find the german press release here and the english press release here.

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Open spots for the Translational Immunology School


January 08, 2018

 

Dear Cluster members and associated scientists,
we would like to announce that we have a limited number of Cluster fellowships for the Translational Immunology School (TIS) 2018. 
You can apply for a fellowship that covers travel costs and the registration fee, including courses, accommodation, full board and social program.
What? Translational Immunology School (please find more information here: http://web.dgfi.org/translational-school/2018/index.html and in the attachment)
When? March 15 – 17, 2018 
Where? Resort Schwielowsee - Potsdam
For whom? Cluster PhD students and postdocs
Application deadline? January 12, 2018
What do I have to do to apply for a fellowship?
Send a letter of motivation, a letter of recommendation and an abstract (in word format) before January 12, 2018 to c.drescher@uni-bonn.de
If you would like to apply but can’t submit your documents until Friday, January 12, please contact Catherine Drescher.

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Cluster member Heneka publishes in Nature


December 21, 2017

 

Another great publication completes this fantastic year 2017.
Cluster member Prof. Heneka from the German Center for Neurodegenerative Diseases (DZNE) and his colleagues could publish their findings in the well-known Journal Nature.
According to a study now published in the journal “Nature”, inflammatory mechanisms caused by the brain’s immune system drive the progression of Alzheimer’s disease. These findings, which rely on a series of laboratory experiments, provide new insights into pathogenetic mechanisms that are believed to hold potential for tackling Alzheimer’s before symptoms manifest. The researchers envision that one day this may lead to new ways of treatment. Further institutions both from Europe and the US also contributed to the current results.
Congratulations to this amazing achievement!
Publication: “Microglia-derived ASC specks cross-seed ß-amyloid in Alzheimer’s disease”, Carmen Venegas, Sathish Kumar et al., Nature (2017), DOI: 10.1038/nature25158
Find the german press release here and the english press release here.

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Immunity Publication by Prof. Schultze and Dr. Schlitzer


December 20, 2017

 

A new study by cluster member Prof. Joachim Schultze and Dr. Andreas Schlitzer was recently published in the renowned journal Immunity.
When the immune system mobilizes its troops, antigen-presenting cells play an important role. They can emerge from white blood cells (monocytes) that circulate in the blood. An international research team under the leadership of the University of Bonn has now taken a closer look at these important helpers. The research revealed that the monocyte-derived cells are not identical descendants, but rather a very diverse mixture. This finding is important for the further development of tailor-made immunotherapies for combating tumor cells.
Publication: Cellular differentiation of human monocytes is regulated by time-dependent IL4 signalling and NCOR2, Immunity, DOI: 10.1016/j.immuni.2017.11.024

Find the german press release here and the english press release here.

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We are looking for a Data Scientist in Bioinformatics and Systems Biology


December 19, 2017

 

The Cluster of Excellence ImmunoSensation is looking for a Data Scientist in Bioinformatics and Systems Biology.
Have a look here to find further information about the job posting.
http://www.immunosensation.de/career/recruitment.html

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Prof. Latz and former member Prof. Hornung receive Leibniz Price


December 14, 2017

 

Congratulation to Prof. Eicke Latz, Institute of Innate Immunity and former cluster member Prof. Veit Hornung, now Gene Center Munich (LMU Munich) for receiving the most prestigious german research award: the Gottfried Wilhelm Leibniz Price.
The Latz Lab has a longstanding interest in deciphering the molecular mechanisms of innate immune receptor activation. In particular, the lab is interested in understanding how innate recep- tors interact with their ligands and how this molecular interaction leads to receptor activation. Recently, we have also focused on the molecular details of the mechanisms that lead to the activation of the NLRP3 and AIM2 inflammasome. Another goal is to devise means to pharmacologically interfere with the activation of innate immune receptors in order to develop novel approaches to treat in ammatory diseases such as Alzheimer’s disease or atherosclerosis.
Eicke Latz and Veit Hornung are two of the most well-known researchers in the field of innate immunology. The two researchers share their price worth 1,25 Million Euro each.
Congratulations!

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Prof. Beck receives American Epilepsy Society Award


December 07, 2017

 

Cluster member Prof. Heinz Beck receives the prestigious Research Recognition Award of the American Epilepsy Society.
The price worth 10.000 Euro was presented at the annual meeting of the American Epilepsy Society in Washington. It is one of the most distinguished prices in the research field of epileptology.
Congratulation to Prof. Heinz Beck for receiving this price.
You can find the german press release here.

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Welcome Event for Doctoral Researchers


November 24, 2017

 

"Welcome Event for Doctoral Researchers" on December 05, 2017. 


Hosts are the Bonn Graduate Center and
the International Office (University of Bonn).

Registration deadline: November 29, 2017 

Date: December 05, 2017 Time: 05pm - 07pm 

Place: Fest- and Senatssaal, main University Building, Regina-Pacis-Weg 3, Bonn 

Including some "Glühwein".

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Open PhD Position in Mass lab


November 17, 2017

 

The Mass laboratory at LIMES Institute, University of Bonn, is seeking a PhD student (m/f)
The research group of Dr. Elvira Mass is looking to recruit a highly motivated PhD student to join her group Developmental Biology of the Innate Immune System. Our research focuses on tissue-resident macrophages and their homeostatic functions. Specifically, we are interested how macrophages impact organ development and function during embryogenesis and postnatal stages on the cellular and molecular level. Based on new developmental and mechanistic knowledge, we seek to improve our understanding of disease pathophysiology and treatment.
We are part of the Life & Medical Science (LIMES) Institute, which is supported by DFG and Cluster of Excellence funding and which offers a great scientific environment for young researchers.
Requirements:
  • Previous experience in cell biology/immunology/hematopoiesis/animal models

  • The willingness to work with mice is a prerequisite

  • basic immunological and histological techniques such as flow cytometry and

    immunofluorescent stainings are beneficial

  • Programming skills (R/Python) for transcriptome analysis are advantageous

    Your application should include:


  • CV

  • brief summary of your previous work experience (max. 1/2 page)

  • contact information of referees and dates when you wish to start the position

  • optional: 1 page research proposal for your PhD project, which builds on the

    study Mass et al. Science 2016
    Enquiries and applications to: Dr. Elvira Mass emass@uni-bonn.de

    Publications:
    Mass E., Jacome-Galarza C.E., Blank T., Lazarov T., Durham B.H., Ozkaya N., Pastore A., Schwabenland M., Chung Y.R., Rosenblum M.K., Prinz M., Abdel-Wahab O., Geissmann F. (2017) A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. doi:10.1038/nature23672

    Mass E., Ballesteros I., Farlik M., Halbritter F., Günther P., Crozet L., Jacome-Galarza C.E., Handler K., Klughammer J., Kobayashi Y., Gomez-Perdiguero E., Schultze J.L., Beyer M., Bock C., Geissmann F. (2016) Specification of tissue-resident macrophages during organogenesis. Science. doi:10.1126/science.aaf4238

    Geissmann F., Mass E. (2016) A stratified myeloid system, the challenge of understanding macrophage diversity. Semin Immunol. doi:10.1016/j.smim.2016.03.016

    Mass E., Wachten D., Aschenbrenner A.C., Völzmann A., Hoch M. (2014) Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling. Dev Cell. doi:10.1016/j.devcel.2014.02.012

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Application Deadline for Spring School extended


November 17, 2017

 

Spring School on Immunology 2018


March 18th to March 23rd, 2018
Ettal, Bavaria


The application deadline is November 30, 2017.

 

 
 

The Spring School on Immunology is an advanced training in specialized immunological topics for scientists with solid knowledge of immunology, e.g. doctoral students in their last year. 

Lectures and interactive discussions cover:
Innate Immunity 
Adaptive Immunity 
Cutting edge: Basics & Perspectives 
Tumor/Allergy/Autoimmunity 
Infection/Vaccination 
Career Planning/Publishing

For full details of faculty, location, application procedure etc. please see http://web.dgfi.org/spring-school/

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Cluster Newsletter Issue 6 released


November 16, 2017

 

We are happy to present you our newest edition of the Cluster Newsletter. This time we focused on new developments within the Cluster and will introduce our newest member to you.
Next to that, three interviews about the use and future of Core Facilities and an overview of all the Core Facilities of the Bonn Technology Campus are provided.
Enjoy reading our Issue 6 of the Newsletter.
You can find the newsletter here or here http://www.immunosensation.de/press_media/links_downloads.html.

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Bonn Immunoscience Days 2017


November 13, 2017 - November 14, 2017

 

Dear colleagues and scientists,

We are pleased to announce that this year's Cluster Science Days will be jointly held with the SFB 704 Symposium. Together we present the Bonn Immunoscience Days 2017!
Please register through our eAntrag system: http://eantrag.immunosensation.net/login.php. If you don't know how to use the system, please follow the attached instructions. You can also register for the conference party here!
What? Bonn Immunoscience Days 2017 (presented by ImmunoSensation and SFB 704)
When? November 13 & 14, 2017
Where? Biomedical Center (BMZ, building 13), University Hospital Bonn, 53127 Bonn
What else? Don’t miss the conference party on November 14, 2017! It’s for free!

Registration and abstract submission are now open. Participation in the meeting is free of charge and open to everyone who is interested.
Childcare during the meeting is provided. CME Points for doctors are available. For more information please contact Nicole Dahms (immunosensation@uni-bonn.de).
Find here the program.

The deadline for registration and abstract submission is September 25, 2017. Registration without an abstract is open until October 13, 2017.

We are looking forward to seeing everyone at the Bonn Immunoscience Days 2017!

With kind regards,
The organizers
ImmunoSensation and SFB 704

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Prof. Förster and colleagues published in Molecular Therapy


November 03, 2017

 

Researchers from the University of Bonn have isolated a molecule that is suitable for the control of contact allergies. The study illuminates a central immune mechanism, which may also play a role in other inflammatory diseases such as arthritis or arteriosclerosis. The results will soon be published in the journal Molecular Therapy, but are already available online.
Last author Irmgard Förster is a member of the Cluster of Excellence ImmunoSensation and a Professor of the LIMES Institute Bonn.

Find the german press release here and the english press release here.

Publication: Lorenz Fülle, Nancy Steiner, Markus Funke, Fabian Gondorf, Franziska Pfeiffer, Julia Siegl, Friederike V. Opitz, Silvana Haßel, Anna Belen Erazo, Oliver Schanz, H. James Stunden, Michael Blank, Carsten Gröber, Kristian Händler, Marc Beyer, Heike Weighardt, Eicke Latz, Joachim L. Schultze, Günter Mayer und Irmgard Förster: RNA aptamers recognizing murine CCL17 inhibit T cell chemotaxis and reduce contact hypersensitivity in vivo; Molecular Therapy; DOI: 10.1016/j.ymthe.2017.10.005

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From Dr. Jekyll to Mr. Hyde of cancer immunotherapy


October 19, 2017

 

Novel immunotherapies can strengthen the body’s own defenses against cancer cells. Treatment of patients with advanced disease can promote partial and complete tumor regressions. However, such strategies also frequently fail. The underlying mechanisms are incompletely understood. An international research team led by the University Hospitals of Magdeburg and Bonn has now discovered a previously unrecognized braking mechanism that limits the efficacy of cancer immunotherapies. Former Cluster Member Prof. Thomas Tüting and Cluster member Prof. Michael Hölzel published these findings in the renowned journal ‘Immunity’ and provide a scientific basis to further develop cancer immunotherapy.
Find the german press release here.
Publication: Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy, „Immunity“, Internet:  https://doi.org/10.1016/j.immuni.2017.09.012

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Cluster Publication in Cell Reports about Cancer Immunotherapy


October 18, 2017

 

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural “brakes” in the immune defense mechanism, which normally prevent an excessive immune response. Prof. Christian Kurts, Dr. Janine Gotot and Christoph Heuser from the Institute of Experimental Immunology have now been able to take off one of these brakes. The study, which involved colleagues from Hamburg and Würzburg, could pave the way for more effective cancer therapies. It is being published in the journal Cell Reports.
Prof. Christian Kurts is a member of the Cluster of Excellence ImmunoSensation.
You can find the german press release here and the english press release here.
Publication: Christoph Heuser, Janine Gotot, Eveline C. Piotrowski, Marie-Sophie Philipp, Christina Johanna Felicia Courrèges, Martin Sylvester Otte, Linlin Guo, Jonathan Leo Schmid-Burgk, Veit Hornung, Annkristin Heine, Percy Alexander Knolle, Natalio Garbi, Edgar Serfling, César Evaristo, Friedrich Thaiss, Christian Kurts: Prolonged IKKβ inhibition improves ongoing CTL antitumor responses by incapacitating regulatory T cells; Internet:  https://doi.org/10.1016/j.celrep.2017.09.082

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ImmunoSensation in for full application


September 29, 2017

 

Our new concept ImmunoSensation2 was selected for full application in the German Excellence Strategy. The selection process was highly competitive and we are proud to be invited to submit a full proposal for the next round.
‚We are all excited and pleased that our concept of the immune sensory system was selected for the second round of the german excellence strategy,' says Prof. Gunther Hartmann, speaker of ImmunoSensation. 'In depth knowledge about the immune sensory system will lead to a better health and successful applications into the clinics. We want to face the challenges of a growing and older population with insights into our immune system.‘
The decision, which clusters are going to be funded is expected for September 2018.
Find here the press release of the University Bonn: https://www.uni-bonn.de/neues/221-2017/

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Nature Publication by Prof. Joachim L. Schultze


September 27, 2017

 

Cluster member Prof. Joachim L. Schultze and colleagues at Yale university published a study about fat tissue in the elderly.
Their findings about malfunctioning fat degradation could explain why fat tissue is accumulating in the belly region especially in the elderly.
The results were published in the high-ranking journal Nature.
Find the german press release here.
Publication: Christina D. Camell, Jil Sander, Olga Spadaro, Aileen Lee, Kim Y. Nguyen, Allison Wing, Emily L. Goldberg, Yun-hee Youm, Chester W. Brown, John Elsworth, Matthew S. Rodeheffer, Joachim L. Schultze & Vishwa Deep Dixit: Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing; Nature; DOI: 10.1038/nature24022

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Dr. Anna Brewitz receives Otto-Westphal PhD Award


September 18, 2017

 

Congratulation to Dr. Anna Brewitz from the Lab of Prof. Wolfgang Kastenmüller (Institute for Experimental Immunlogy) for receiving the Otto-Westphal PhD award 2017.

Here you can find more information about here most recent publication.

Otto-Westphal Thesis Prize (1.500 €)
The German Society for Immunology e.V. (DGfI) annually awards the Otto-Westphal Thesis Prize to one of its members. The prize is awarded for the best dissertation on the subject of immunology that was successfully completed in the German-speaking countries during the last calendar year (as determined by the date of the oral exam).

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Melbourne - Bonn excellence academy BM-AXIS starts


August 25, 2017

 

A new excellence academy: BM-AXIS (Bonn & Melbourne Academy for Exellence in ImmunoSciences/Infection) is getting funded by the Federal Ministry of Education and Research. Within the next 5 years more then 100.000 Euro per year will be used to provide a better scientific transfer between Melbourne and Bonn.
The exchange program for scientific excellence wants to enhance the Bonn-Melbourne activities by sending german scientists to Melbourne and vice versa.
Congratulation to Prof. Christian Kurst, cluster member and spokes person of the newly established BM-AXIS.
Find the german press release here.

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How does the immune system work? Video by Prof. Gunther Hartmann


August 14, 2017

 

Cluster member Prof. Gunther Hartmann explains in this video what the immune system is doing and how it works.
Together with Uni Bonn TV he answers the question, if we can fight the flu without using drugs or medicine.
You can find the interesting video here.

https://www.youtube.com/watch?v=fABnR9VjiKc

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Mentoring Program (in german) for PostDocs with open spots


August 10, 2017

 

Liebe Cluster-Postdoktorandinnen,

im Rahmen des neu startenden Mentoring- und Trainingsprogramms MeTra sind noch einige Plätze für Postdoktorandinnen (1.-3. Jahr) frei. (Die Plätze für Doktorandinnen sind bereits ausgebucht.)

Die Bewerbungsfrist läuft noch bis zum 15. August.
Die Teilnahmegebühren i.H.v. 200,- € wird den Teilnehmerinnen durch das Exzellenzcluster ImmunoSensation erstattet.

Wer interessiert ist, momentan aber in Urlaub, kann sich auch vorab gerne per email bei Dr. Martina Pottek (mpottek1@uni-bonn.de) melden, um das weitere Vorgehen zu vereinbaren.

Der erste Workshop (erfolgreiche Förderanträge schreiben) findet am 16./17. Oktober statt.
Wichtiger Hinweise: die Trainingsveranstaltungen werden in deutscher Sprache gehalten, daher sind ausreichende Sprachkenntnisse notwendig.
 
Fortgeschrittene Postdocs ab dem 3. Jahr, Habilitandinnen, Juniorprofessorinnen können sich noch bis Oktober bewerben.
Detaillierte Hintergrundinfos zum Programm und zu den Bewerbungsmodalitäten finden sich auf folgender Homepage: www.metra.uni-bonn.de

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Joint Symposium HCM and ImmunoSensation


August 08, 2017

 

We would like to announce the joint symposium from the Hausdorff Center for Mathematics & ImmunoSensation on August 28 & 29, 2017.

Title: Symposium of Biomathematics
Date: August 28 (Monday) & 29 (Tuesday), 2017
Time: 09:00 am - 01:15 pm
Location: Lipschitz-Saal 1.016, Endenicher Allee 60, 53115 Bonn

No registration needed & no registration fee.

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Cluster member Prof. Nöthen received teaching award


July 06, 2017

 

Prof. Markus M. Nöthen, director of the Institute of Human Genetics, received a teaching award by the Rheinische-Friedrich-Wilhelms University Bonn for his outstanding commitment.
The teaching awards were handed over at the University Celebration in the Telekom Dome. According to the size and number of students, the faculties are allowed to nominate different instructors for the award. The medical faculty of the Rheinische-Friedrich-Wilhelms University handed over an award to Dr. Christof Völker, Institute for Biochemistry and Molecular Biology, next to Prof. Markus Nöthen.
Find the german press release here.

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Video about our Day of Immunology 2017


July 04, 2017

 

Dear Cluster members and friends,
we are happy to share with you the video about our Day of Immunology 2017, April 29 on the Marktplatz in Bonn.
Have a look for yourself: https://www.youtube.com/watch?v=Fvr_PhqfysA
A big thank you to the Bundesstadt Bonn - Economic Development Office for letting us on the Marktplatz and Uni Bonn TV for the video.
Next year we will be back with our Day of Immunology celebration in Bonn.
Mark your calenders for May 5th, 2018 and celebrate with us the excellent science of Bonn.

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Cluster Research paper in Gut published


June 21, 2017

 

Scientists of the University Hospitals in Bonn and Essen could show what drives one of the much-feared complications of gastrointestinal operations.
Scientists Prof. Christian Kurts from the Institute of Experimental Immunology Bonn, member of the Cluster of Excellence ImmunoSensation, and Prof. Daniel Engel from the Department of Immunodynamics Essen published their most recent findings in the Journal Gut.
They showed that bacteria are recognized by specialized immune cells in the gut, which can lead to a paralysis of the intestines. This is called post-operative ileus.
Find more information about the publication here.

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New Newsletter released


June 14, 2017

 

Shortly before holiday season we gathered all important information throughout the last 6 months. Now you can find all the things that happened in the Cluster of Excellence ImmunoSensation in our newest edition of our Newsletter. Don't miss it and show your parents and loved ones in which exciting scientific area you are working in.
Enjoy reading it and we are happy to take suggestions for further topics that should be covered.
Find our newsletter edition 5 here and http://www.immunosensation.de/press_media/links_downloads.html here.

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Application open for a female PostDoc Scholarship until July 31


June 06, 2017

 

The University Bonn invites all female PostDocs to apply for the Annemarie Schimmel-Scholarship 2017.
It covers 2.300 Euro monthly for up to 12 months with the option of an extention of 6 more months. It is open for female PostDocs up to three years after they finished their PhD.
Find more information here: https://www.gleichstellung.uni-bonn.de/

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Cluster member Prof. Hörauf elected chairman of DNTD Network


May 29, 2017

 

Cluster member Prof. Achim Hörauf, director of the Institute of Medical Microbiology, Immunology and Parasitoloy University Clinics Bonn, was elected chairman for the German Network to combat Neglected Tropical Diseases (DNTDs) May 18 in Berlin.
The German Network against neglected tropical diseases forms a national platform in Germany designed to heighten awareness of this group of diseases and raise the level of commitment in Germany to fighting them. The German network wishes to support the World Health Organization (WHO) in controlling, eliminating or even eradicating at least ten of the 18 neglected tropical diseases. 
Find here the german press release.

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ImmunoSensation and HCM are looking for new Professors and PostDocs


May 16, 2017

 

The University of Bonn with its two Clusters of Excellence, the Hausdorff Center for Mathematics, and ImmunoSensation, intends to significantly strengthen the existing collaborations between these two clusters and to establish an internationally visible research group in the field of mathematical modeling in life and medical sciences. In this context, it invites applications for
three temporary Professorships (W2) for 5 years
and
three research positions (E13) for 3 years for Postdocs
find here more information how to apply.
Applcation deadline for the professorships are approaching.

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Cannabis reverses ageing processes in the brain


May 09, 2017

 

Memory performance decreases with increasing age. Cannabis can reverse these ageing processes in the brain. This was shown in mice by scientists at the University of Bonn with their colleagues at The Hebrew University of Jerusalem (Israel). Old animals were able to regress to the state of two-month-old mice with a prolonged low-dose treatment with a cannabis active ingredient. This opens up new options, for instance, when it comes to treating dementia. The results are now presented in the journal Nature Medicine.
Prof. Andreas Zimmer and Prof. Joachim L. Schultze are both members of the Cluster of Excellence ImmunoSensation.
Publication: A chronic low dose of delta9-tetrahydrocannabinol (THC) restores cognitive function in old mice, Nature Medicine, DOI: 10.1038/nm.4311
Find the german press release here and the english press release here.

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Day of Immunology 2017


May 08, 2017

 

The Day of Immunology was a huge success.
On Saturday, April 29, we celebrated this years International Day of Immunology with an exhibition of some of our research that's been conducted within the Cluster.
The focus of the exhibition was on widespread diseases such as Atherosclerosis, Alzheimer's or Malnutrition. Walk-in models of the brain, the mouth and an artery were not only playgrounds for kids but also informative and inspiring spots.
Thanks to all our researchers and the City of Bonn who contributed to this amazing event.
Find here our Info-Displays: Alzheimer's, Atherosclerosis, Tumor Vaccination, Influenza and Malnutrition.

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Science Publication: Where do immune cells come from?


May 05, 2017

 

Congratulation to Cluster member Dr. Andreas Schlitzer, PD Dr. Marc Beyer and Prof. Dr. Joachim L. Schultze from the LIMES Institute Bonn. They recently published their newest findings about dendritic cell progenitors in Science.
Publication: Mapping the human DC lineage through the integration of high-dimensional techniques, Science, DOI: 10.1126/science.aag3009
Find the german press release here and the english press release here.

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Cluster speaker Prof. Gunther Hartmann gives a public lecture


May 04, 2017

 

Cluster speaker and director of the Institute for Clinical Chemistry and Clinical Pharmacology at the University Hospital Bonn Prof. Gunther Hartmann gives a public lecture on May, 17 6pm.
The lecture will take place in the Old Town Hall Bonn (Althes Rathaus Bonn, Gobelinsaal) and the entrance is free.
The lecture is organized by the Adult Education Center of Bonn and is entitled:
Erbgut im Wettstreit mit Viren - wie unser Immunsystem die Gefahr meistet.

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New Cluster Publication in Nature Immunology


May 03, 2017

 

Cluster member Prof. Joachim L. Schultze and his colleague Dr. Thomas Ulas, both from the LIMES Institute of the University of Bonn, published their finding in the highly ranked journal Nature Immunology.
They showed that babies are born with an immune system which has a reduced activity. That prevents the immune system to overreact after the babies are being born and come in contact with millions of pathogens and foreign substances.
The new findings can lead to the development for new therapies against a life-threatening sepsis which can occur in premature infants.
Publication: Thomas Ulas et al.: S100 alarmin-induced innate immune programming protects newborn infants from sepsis; Nature Immunology; DOI: 10.1038/ni.3745
Find the german press release here.

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Girls' Day 2017


April 28, 2017

 

As last year we celebrated the Girls' Day in the Excellence Cluster ImmunoSensation by inviting 6 girls to one of our labs.
This year Dr. Annkristin Heine and her team showed them how to isolate DNA out of tomatoes.
You can find pictures of the day here.

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New patent helps to boost immune system against cancer cells


April 27, 2017

 

Researchers at the ImmunoSensation cluster of excellence at the University of Bonn have managed to do what many scientists dream of: together with researchers from the USA, they have patented new molecules that allow the immune system to be directed against tumor cells. The license has already given the University of Bonn a first payment – and the scientists also gained a share. An exemplary success within the biomedical research landscape in Germany.
Cluster scientists Prof. Gunther Hartmann, Prof. Winfried Barchet and Dr. Thomas Zillinger were part of that ground-breaking research.
Please find the german press release here and the english press release here.

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Young Scientists visit ImmunoSensation


March 29, 2017

 

Seven young scientists visited the ImmunoSensation Cluster of Excellence on March 31 in the context of the German juFORUM e.V.
Deutsches Jungforschernetzwerk - juFORUM e.V. is a network by and for young scientists and other people interested in STEM (science, technology, engineering and mathematics). It was established in 2000 by former participants of Jugend forscht, a German youth science competition.
They visited the central laboratory and the Institute for Experimental Immunology.
You can find more pictures on our picture site and an article about the success of the day here.

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Cluster goes Charity 2017: Shoes for little hearts


March 23, 2017

 

With the help of our cluster members - Immuna and Immuno could deliver more than 7 big packages of shoes for Kinderherzen - Fördergemeinschaft Deutsche Kinderherzzentren e.V.!
Thank you all for your help.

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New Publication by Cluster member Prof. Regina Betz


March 14, 2017

 

Cluster member Prof. Regina Betz from the Institute of Human Genetics published her recent findings in the Journal of Clinical Investigations.
Dowling-Degos disease is a hereditary pigmentation disorder that generally progresses harmlessly. However, some of those affected also develop severe skin inflammation. An international team of researchers under the leadership of the University of Bonn has now found a cause for this link. Their knowledge comes thanks to an animal that is known among aquarium owners for its characteristic pigmentation: the zebrafish.

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ImmunoSensation participated in the University Science Rallye 2017


March 10, 2017

 

The Cluster of Excellence ImmunoSensation participated for the first time in the Science Rallye of the Rheinische Friedrich-Wilhelms-University of Bonn.
Here young scientist of the age between 13 and 17 can participate in a rallye around the campus in Bonn Poppelsdorf. With interesting stops at the mathematics or the geology department attending pupils get to know the University and its departments.
The Cluster of Excellence ImmunoSensation displyed with the group of Prof. Kolanus from the LIMES Institute a parcour. Here you could learn what the immune systems consists off, what the immune cells are doing and how the immune system distinguishes between various pathogens. We had a lot of fun participating and looking forward to next years Science Rallye.

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Kinderuni - Finding the missing piece: How to develop drugs?


March 06, 2017

 

The Kinderuni from the Rheinische Friedrich-Wilhelms-University Bonn can lead to an official diploma, if the kids attend at least 10 lectures in one year.
Cluster member Prof. Matthias Geyer gave an introduction on 'How drugs are being developed?'. 
Again lots of children attended the lecture and challenged Matthias Geyer with lots of interesting questions afterwards.

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TAKeOFF being funded by Federal Ministry of Education and Research


March 02, 2017

 

Cluster member Prof. Achim Hörauf and his lab are now funded by the Federal Ministry of Education and Research. Five german-african networks fighting infectious disases like malaria or dengue fiever were chosen. The network TAKeOFF is one of them.
Mainly in Africa and Asia, more than 200 million people are parasitised by filarial nematodes (roundworms), which cause the neglected tropical diseases lymphatic filariasis, loiasis and onchocerciasis. By establishing a Filarial Clinical Trial & Research Platform (F-CuRE), the TAKeOFF consortium aims to harmonise the procedure for clinical trials in filariasis. To improve treatment regimens for morbidity control of filarial and non-filarial lymphedema (podoconiosis), the partners will conduct multinational clinical trials in sub-Saharan Africa, thereby addressing patient needs as well as the science behind these diseases.
Find the german press release here.

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Master student from Syria featured in german news


February 23, 2017

 

The Master student Mohammed Hajo working in the lab of Jasper van den Boorn in the Insitute of Clinical Chemistry and Clinical Pharmacology is featured in german news.
He is originally from Syria and came to germany in 2015. He conducts his master thesis in the field of immunotherapies for cancer and maybe wants to conduct a PhD afterwards.
Find the german article here.

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New Cluster publication: How do T cells end up where they are needed?


February 20, 2017

 

A new cluster publication recently published in the European Journal of Immunology by cluster member Prof. Waldemar Kolanus from the LIMES (Life and Medical Sciences) Institue shows how T cells are directed to the places where they are needed the most.
Find the german press release here.

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Killer cells and how they are recruited: new publication in Immunity


February 14, 2017

 

ImmunoSensation member Prof. Kastenmüller and his group recently published a paper in Immunity about how killer cells are recruited and which mechanism apply to build up this army.
Find the german press release here and the english press release here.

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Become a part of the Students' Retreat Orga Team


February 01, 2017

 


Dear IITB members and Cluster PhD students (aka future IITB members),








During last year's IITB Network Meeting some of you suggested to make a „full grown“ PhD Students’ Retreat out of it next time. And that time is now! 


What we offer

A two-days Network Meeting to get to know each other and the groups of ImmunoSensation

Scientific and non-scientific program (without PIs)

Career talks with invited guests

Fun!


What we need

You!


What for?

An organization team to

- agree on date and place

- shape the program (the scientific and the non-scientific part)

- suggest and invite guests


You are warmly invited to join the organization team. If you want to join the team, please send a short email to c.drescher@uni-bonn.de until Monday, February 6, 2017 and we will doodle a date for our first meeting.


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Apply for our new Master 'Medical Immunosciences and Infection'


January 27, 2017

 

Our new Master Program 'Medical Immunosciences and Infection' starts this autumn. The application deadline is end of march 2017.
Here students will learn how the immune system works and how it interacts in times of disease with various other organs. In four semsters and completely in english, students will get to know cellular and molecular processes in the immune system in detail.
Find the german press release here and more information for the application process here.

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Newsletter Issue 4 now online


January 24, 2017

 

Find here our most recent Newsletter - already in its 4th edition.

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Travel Grant Application is open Now


January 10, 2017

 

Applications for the first round of ImmunoSensation Travel Grants in 2017 can now be submitted!

"Travel Grant 1: Technical Exchange" and "Travel Grant 2: Meetings and Seminars" are for IITB members only! If you are PhD student within the Cluster, but not IITB member, you should consider applying for IITB membership.

Non-IITB members (e.g. other students and postdocs) who want to write a blog article can apply for "Travel Grant 3: Blog Support". Funding is available up to 500 € per application.

Please be aware that ImmunoSensation Travel Grants will be awarded on a competitive basis and there is no guarantee for funding. Travel support granted by the Cluster can only be used for reimbursement. That means, travel costs and meeting fees have to be paid in advance by the applicant (or the applicant’s PI/ lab).

Applications will only be accepted via our eAntrag system http://eantrag.immunosensation.net/
Please send me a short email to Dr. Catherine Drescher and we will open your application.
If you encounter any problems with the eAntrag system or have any further questions, please do not hesitate to contact Dr. Catherine Drescher.Application deadline is March 6, 2017.

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Apply for the Translational Immunology School until January 13


January 10, 2017

 

March 16 - 18, 2017
Translational Immunology School (TIS)
Dear IITB members,

I am happy to announce that ImmunoSensation is now cooperation partner of the Translational Immunology School (TIS)!

IITB members can apply for a fellowship that covers the registration fee, including courses, accommodation, full board and social program.

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Cluster Publication in Science Immunology by Prof. Schultze


December 19, 2016

 

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response. Scientists of the University Hospital Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and the LIMES (Life and Medical Sciences) Institute of the University of Bonn gained substantial knowledge of human dendritic cells, which might contribute to the development of immune therapies in the future. The results were recently published in the Journal “Science Immunology”.
Prof. Schultze is a member of the ImmunoSensation Cluster of Excellence and published this study in conjunction with researchers from Erlangen.
Publication: Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment, „Science Immunology“, DOI: 10.1126/sciimmunol.aai7677
Find the german press release here and the english press release here.

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Celebrating 20 years of Nucleic Acid Immunity


December 09, 2016

 

On Saturday, December 10, a Symposium on Celebrating 20 years of Nucleic Adic Immunity will be held at La Redoute - Bonn Bad Godersberg.
Worldwide renown experts in the field of nucleic acid research such as Gunther Hartmann, Hermann Wagner or Veit Hornung will give a scientific overview of the findings within the last two decades of cutting edge science and future perspectives.
Outstanding speakers will share their insight and enthusiasm and whether you are a newcomer or an expert in this exciting area of research, you will enjoy this symposium.

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New treatment option for breast cancer found by Cluster scientists


November 25, 2016

 

Cluster Scientist Prof. Matthias Geyer and his lab member Dr. Ann Katrin Greifenberg found out that the active compound Dinaciclib could prevent the resistance of breast cancer towards chemotherapy.
They published their findings in the Journal of 'Cell Reports' in collaborations with groups from USA, Spain and Germany.
Find the german press release here.

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Andreas Schlitzer granted with Post Doctoral Prize


November 10, 2016

 

Dr. Andreas Schlitzer member of the Excellence Cluster ImmunoSensation and the LIMES Institute Bonn received the Post Doctoral Prize of the Robert Koch Foundation.
He was granted the prize worth 5.000 Euro in the area of immunology in recognition of his findings of the development and differentiation of myeloid cells.
Please find the german press release here.

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New Biotech IFM Therapeutics from Cluster members


November 03, 2016

 

IFM Therapeutics, a biopharmaceutical company developing a portfolio of first-in-class small molecules targeting the innate immune system, announced the formation of a German subsidiary, IFM Therapeutics GmbH, and the establishment of a research site at the Institute of Innate Immunity within the University of Bonn.
Professor Eicke Latz, Director of the Institute, and Professor Matthias Geyer, Department Head for Structural Immunology, are scientific Co-founders of IFM Therapeutics. IFM Therapeutics’ scientific mission is to generate therapeutic products that can enhance innate immune system activity to attack cancer and that can decrease innate immune system activity in autoimmune disorders and diseases caused by excessive inflammation.
The Institute of Innate Immunity is part of the Excellence Cluster ImmunoSensation at the University of Bonn. IFM’s site at the University of Bonn provides unique access to deep innovative biology as well as cutting edge clinical sciences.

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Winter School on Immunology, Genomics and Bioinformatics


October 17, 2016

 

We proudly present our first Winter School "Immunology meets Genomics and Bioinformatics".
Registration is now open and we are looking forward to your participation!

What: Winter School "Immunology meets Genomics and Bioinformatics"
When: 03.01. - 07.01.2017
Where: Obergurgl, Austria
Speakers: Please see attached poster
Participants: IITB members and young postdocs; places limited to 30
Fee: 850,- Euro*, covering accommodation and meals

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IITB Blog article: Physics and Immunology


October 14, 2016

 

Our IITB Blog Team once again has outdone itself and wrote a summary about why you need physics in immunology.
See what two of our ImmunoSensation scientists think about physics.
Check out the IITB Blog article here.

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Our Annual Report 2015 now online


September 29, 2016

 

We are proud to present our annual report 2015.
Here you can find our scientific highlights in our Research Areas from 2015 and reports from past events like the DAMPs & HMGB1 meeting and lots more.

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IITB Blog Interview with Cluster Member Prof. Pankratz


September 22, 2016

 

The IITB Blog Team conducted an interview with our Cluster member Prof. Michael Pankratz.
http://www.immunosensation.de/blog/?p=1567

Michael Pankratz and his team is studying how the brain controls behavior and metabolism, using Drosophila as a model organism.
Have a look at his homepage here to get more insight into his research.
In his interview Michael Pankratz tells you about his research and gives advive for young scientists.

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Ground-Breaking Ceremony BMZ II


September 05, 2016

 

On Wednesday, August 31 2016, the ground-breaking ceremony for the new BMZ II - Biomedical Center II - took place.
Here research groups of the ImmunoSensation Cluster of Excellence and the DZIF - German Center for Infection Research- will be housed.
With the support of the Minister for Innovation, Science and Research of the State of North Rhine-Westphalia - Svenja Schulze - representatives of the ImmunoSensation Cluster of Excellence (Prof. Gunther Hartmann), the University Hospital Bonn (Prof. Wolfgang Holzgreve), the DZIF (Prof. Achim Hörauf), the University of Bonn (Prof. Michael Hoch) and the Medical Faculty (Prof. Nicolas Wernert) undertook the ground-breaking ceremony and gave speeches about the development of the immunological research in Bonn.
Find the german press release here.

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Register for a GenTSV course at the IMMIP


August 18, 2016

 

September 21st/22nd - Training courses according to § 15 par. 2 and 4 genetic technology safety regulations - GenTSV
Project manager and agents for biosafety are according to Genetic Engineering Law obliged to possess knowledge required for their tasks. These must be purchased by visiting an officially recognized training course. This training course is recognized by the district government of Dusseldorf. The recognition is valid nationwide.
The course covers the basic microbiological principles for the assessment of the risk potential of organisms, the precautions for laboratories, production and releases and associated legislation.
The course will be held at the IMMIP = Institute of Medical Microbiology, Immunology and Parasitology, University Bonn
Please find more information here.

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Science Publication by Cluster Member PD Dr. Marc Beyer


August 10, 2016

 

In the newest issue of Science a publication by the group of Marc Beyer and Joachim Schultze, both members of the Excellence Cluster ImmunoSensation and the LIMES (Life and Medical Sciences) institute, was released.
Here they show how to use singe cell RNA sequencing to solve the mystery of the origin of tissue-resident macrophages.
The Publication was the first of the newly established single cell genomics and epigenomics unit of the DZNE (German Center for Neurodegenerative Diseases) in cooperation with the University of Bonn.
Publication: Elvira Mass, Ivan Ballesteros, Matthias Farlik, Florian Halbritter, Patrick Günther, Lucile Crozet, Christian E. Jacome-Galarza, Kristian Händler, Johanna Klughammer, Yasuhiro Kobayashi, Elisa Gomez-Perdiguero,  Joachim L. Schultze, Marc Beyer, Christoph Bock, Frederic Geissmann: Specification of tissue – resident macrophages during organogenesis. Science. DOI: 10.1126/science.aaf4238
Find the german press release here.

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Nucleic-acid sensing review in Nature Reviews Immunology published


August 09, 2016

 

The Excellence Cluster member Prof. Gunther Hartmann and Dr. Martin Schlee from the Institute of Clinical Chemistry and Clinical Pharmacology (University Hospital Bonn) released a review about the sensing of nucleic-acids to discriminate self from non-self.
The review was published in the well-known journal Nature Reviews Immunology.
Publication: Discriminating self from non-self on nucleid acid sensing. Martin Schlee and Gunther Hartmann. Nature Reviews Immunology (2016). doi:10.1038/nri.2016.78

Find the link to the review here.

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Participate in the eQTL-study


August 01, 2016

 

The eQTL-study of the University Hospital Bonn in coorperation with the Cluster of Excellence ImmunoSensation is looking for volunteers to donate blood.
After the job is done, you'll get a free breakfast, 20 Euro and the satisfying feeling of helping to stretch the boundaries of scientific knowledge.
Find here the german press release.
People interested in taking part in the study can reach out here:
Phone 0228-28719155 or E-Mail spende.kqt@ukb.uni-bonn.de 

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Apply for the 27th European Students’ Conference in Berlin


July 27, 2016

 

Find information about how to attend the European Students' Conference, which will take place from Sept 28th until Oct 1st in Berlin.
More information can be found here.

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Fighting dangerous bacteria without using antibiotics


July 21, 2016

 

Dr. Zeinab Abdullah (Institute of Experimental Immunology, University Hospital Bonn) and Prof. Percy Knolle (Institute of Molecular Immunology and Experimental Oncology, TU Munich) both member of the Cluster of Excellence ImmunoSensation could discover the cause of infections in patients with cirrhosis of the liver. These results were recently published in the high-ranking journal 'Gut'. With the help of their findings life-threatening infections can now be treated by strengthening the immune response itself and thereby circumventing the usage of antibiotics.
Find here the german and english press release.
Publication: Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis, "Gut", DOI: 10.1136/gutjnl-2015-311224

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Study published in the Journal of Experimental Medicine by Prof. Wilhelm


July 18, 2016

 

Prof. Christoph Wilhelm, member of the Cluster of Excellence ImmunoSensation, and collegeagues from the National Institutes of Health (NIH) in Bethesda (USA) published their recent work about innate lymphoid cells in the Journal of Experimental Immunology. It deals with the question how parasites can be eliminated from the body in times of starvation. The team from Prof. Wilhelm (Institute of Clinical Chemistry and Clinical Phamacology, University Hospital Bonn) and Prof. Yasemine Belkaid (NIH, USA) could show that during times of low calory intake and parasitic infection innate lymphoid cells switch to lipid metabolism rather using sugar as an energy source.
Find here the german press release.
Publication: Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection, The Journal of Experimental Medicine, DOI: 10.1084/jem.20151448
www.jem.org/cgi/doi/10.1084/jem.20151448

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New IITB Blog article


July 11, 2016

 

The IITB Blog Team has been busy writing new articles about recent and upcoming events. They also featured a software, produced by a PhD student from the Cluster of Excellence in Prof. Hornungs group, which definitively will boost your research.
Recently released blog articles:
A range of software tools to boost your research - Interview with Jonathan Schmid-Burgk
What will we do after our PhD? - Article about career opportunities
The autumn school in Merseburg - Event summary about an immunology autumn school
'Microglia in the brain' - Congress summary from a Keystone meeting
If you want to write something about you favourite immunology topic as well, don't hesitate to contact the IITB Blog Team.

Read more...

Bonner Wissenschaftsnacht 2016


July 01, 2016

 

We participated at the Bonner Wissenschaftsnacht 2016 and with the support of the Institute of Zoology (University Bonn) we could show what kind of an immune system sharks have and weather jellyfish can fight bacteria.
Find here our flyer for the Bonner Wissenschaftsnacht 2016, if you want to gain more insights into the immune system of animals living in the ocean.
Thanks to our helpers from the ImmunoSensation Cluster of Excellence for their time and patience in explaining everything.
Pictures by Johann Saba (Unternehmenskommunikation, UKB).

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Cluster helps donating backpacks for Mary's Meals


June 28, 2016

 

With the help of our cluster member, we could donate 16 backpacks, which will be send to children in Malawi and Liberia helping them to go to school.
The initiative comes from Mary's Meals and is supported by the Company Medical Officer at the University Clinics Bonn.
Thank you for all your help.

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Natural Killer cell memory - cluster publication in Immunity


June 08, 2016

 

The team of Dr. Jasper van den Boorn, Prof. Dr. Gunther Hartmann and Prof. Dr. Veit Hornung have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin. They recently published a paper in the high-ranking journal Immunity about the newly found memory function of natural killer cells. They have been able to show that natural killer cells can remember pigmented cells after they came into more frequent contact with a specific contact allergen. The findings could help to establish new treatment options for malignant melanoma.

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New Blog article: PhD vs Dr.rer.nat


June 06, 2016

 

The IITB Blog released a new article recently and presents you a (kind of) comprehensive study about similarities and differences between PhD and Dr.rer.nat.
Find the newest article here: http://www.immunosensation.de/blog/?p=1241
If you want to participate in the Blog Team or have ideas for new topics that should be covered just send the IITB Blog a message.
blog(at)immunosensation.de

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Immune cells in our brain? Kinderuni lecture with Annett Halle


May 18, 2016

 

The Kinderuni from the University Bonn can lead to an official diploma, if the kids attend at least 10 lectures in one year.
Cluster member Annett Halle gave an introduction on 'Why do we need immunce cells in our brain?'. 
As you can see her lecture was a huge success and everyone took notes, paid attention and tackeled Dr. Halle afterwards with a tough Q&A session.

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Fine-tuning for intestinal immune cells published in Scientific Reports


May 17, 2016

 

Cluster member Prof. Irmgard Förster from the LIMES institute and her team recently published an article about the fine-tuning for intestinal immune cells in Scientific Reports. 
The study shows an influence of food in the intestinal immune system via the regulation of an important controller - the Ah receptor.

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Apply for a Junior Research Group in the Competence Cluster Diet-Body-Brain


May 16, 2016

 

The Competence Cluster in Nutrition Diet-Body-Brain invites contributions for a symposium on Nutrition and Microbiota.
This symposium will be held in Bonn on June 22nd, 2016 and is intended to establish a Junior Research Group (W1/W2 tenure-track) at the Department of Nutrition and Food Sciences at Bonn University.
Please submit your abstract and CV to the cluster office no later than June 5th, 2016.

Please find more information here and on the cluster's website www.diet-body-brain.de.

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Rigontec ranked as outstanding european academic spinout 2015


May 11, 2016

 

Rigontec GmbH is a privately held German biopharmaceutical company, which is a successfull spinout from members of the ImmunoSensation Cluster at the University Bonn.


Rigontec was launched in 2014 with the scientific co-founder Prof. Gunther Hartmann and Prof. Veit Hornung, both member of the ImmunoSensation Cluster.


In the recently released issue of Nature Biotechnology a feature about companies as academic spinouts which develop ground-breaking technologies can be found. Here Rigontec is the only successful european science company coming out of academia.

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Cluster Member Prof. Neumann receives prestigious german grant


May 06, 2016

 

Prof. Neumann, member of the excellence cluster ImmunoSensation in Bonn receives a funding over 1.5 million Euro in conjunction with Prof. Dr. Thomas Scheper (Leibniz University Hanover) and Prof. Dr. Thomas Langmann (University Clinics Cologne).
The grant from the Federal Ministry of Education and Research is dedicated for the research against age-related macular degeneration (AMD).
Under the direction of Prof. Neumann in Bonn the scientists want to further enhance a therapy of AMD with the use of a sugar naturally produced in the body.
Find the german press release here.

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Cluster scientist are highly cited in the field of clinical chemistry


May 04, 2016

 

Cluster scientists Prof. Hornung, Prof. Latz and Prof. Hartmann are among the most cited scientist in the fied of clinical chemistry and labratory medicine. 
The second most cited paper in this field in the years 2010 until 2014 was the cluster cooperation by Prof. Hornung and Prof. Latz.
NLRP3 inflammasomes are required for artherogenesis and activated by cholesterol chrystals Nature 2010
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E.

Among the most cited scientists in this field in germany can Prof. Hornung be found on 4th place and Prof. Hartmann on 10th place.
Out of 20 scientists listed here, 5 are part of the ImmunoSensation Excellence Cluster in Bonn.

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New Blog article: What to do after graduation?


April 28, 2016

 

The IITB Blog released a new article recently and presents you an interview with Franziska Frey about her work in Medical Writing and Project Management.
Find the newest article here: http://www.immunosensation.de/blog/?p=1215

If you want to participate in the Blog Team or have ideas for new topics that should be covered just send the IITB Blog a message.
blog@immunosensation.de

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Cluster goes Charity: shoes for children


April 21, 2016

 

With the help of our cluster members - Immuna and Immuno could deliver more than 25 kg of shoes for Kinderherzen - Fördergemeinschaft Deutsche Kinderherzzentren e.V.!
Thank you all for your help.

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Prof. Kastenmueller becomes full faculty member of the F1000


April 21, 2016

 

Cluster member Prof. Wolfgang Kastenmueller was awarded as a full faculty member of the F1000.
The F1000 is composed of more than 5,000 leading scientists from different areas of biology and medicine and recommends the most imporant articles in their fields.
Find more information about the F1000 here.

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Fighting cancer: Cluster mathematicians and immunologists cooperate


April 11, 2016

 

Cluster members Anton Bovier of the Institute of Applied Mathematics and Thomas Tüting of the Department of Dermatology published a paper in Scientific Reports concerning a new model for immunotherapies against cancer. The findings could lead to better treatment options against tumours, which do not respond to the given medication.

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Cluster scientists tackle atherosclerosis with the help of sugars


April 08, 2016

 

Members of the ImmunoSensation Cluster under the responsibility of Prof. Eicke Latz recently published a paper (find the publication here) in Science Translational Medicine in which they could show a role of the ring-shaped sugar cyclodextrin in promoting the regression of atherosclerosis. In a joint effort with Cluster Members Joachim Schultze (LIMES), Georg Nickenig (Medical Faculty University Bonn) and Dieter Lütjohann (Institute of Clinical Chemistry and Clinical Pharmacology) the study revealed a reduction in size of the atherosclerosis plaques and the load of cholesterol crystals.
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Science Translational Medicine
06 Apr 2016: Vol. 8, Issue 333, pp. 333ra50 DOI: 10.1126/scitranslmed.aad610

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Apply now for the MSc in Immunobiology from the LIMES institute


March 31, 2016

 

In Cooperation with members of the ImmunoSensation Cluster the LIMES (Life & Medical Sciences) Institute established a Master of Science in Immunobiology.

Read more...

New Cluster publication by Dagmar Wachten and colleagues in eLife


March 22, 2016

 

Cluster scientists of the groups of Dagmar Wachten and Benjamin Kaupp developed a new biosensor, which allows to measure nanomolar levels of the second messenger cAMP. The sensor makes it possible to study cAMP signaling with high precision, even in subcellular compartments. Using this new biosensor, the scientists of the Minerva Max Planck Research Group "Molecular Physiology" headed by Dagmar Wachten and of the Department "Molecular Sensory Systems" headed by Benjamin Kaupp revealed how the production of cAMP is regulated in the flagella of sperm cells from mice.
Press release: http://www.caesar.de/1575.html

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The Cluster Times Issue No. 2 available!


March 18, 2016

 

Dear "Cluster Times" reader,
We are pleased to introduce Issue No. 2 of "The Cluster Times", the ImmunoSensation newsletter.
Enjoy reading!
Download

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Two-year, EU-funded study reveals positive effects of a nutritional intervention in Alzheimer's Disease


March 17, 2016

 

The LipiDiDiet Consortium has been funded by the 7th Framework Programme (FP7- 211696) of the European Commission and consists of 16 participating institutions. Prof. Lütjohann from the Institute of Clinical Chemistry and Clinical Pharmacology is representing the University Hospital Bonn within this Consortium.
They now presented topline results from the European LipiDiDiet clinical trial as part of a late-breaking presentation at the Advances in Alzheimer's Therapy (AAT) congress. 
This two-year, EU-funded study reveals a medical food in the form of a daily nutritional drink can help to conserve memory, the ability to think and perform everyday tasks, as well as reduce brain shrinkage in people with very early Alzheimer's Disease (AD).
The press release and more details on the study and on the drink "Souvenaid" can be found here
For further information on the European LipiDiDiet study and consortium, visit: http://www.lipididiet.eu

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Cluster groups jointly discover immune factor with high impact on chronic HIV infections


March 07, 2016

 

The members of five Cluster groups could identify the signaling molecule tumor necrosis factor (TNF) as a major player in chronic infections.
In HIV and other chronic infections, TNF is present and silences helper T cells. Without proper T cell help, killer T cells remain inactive and the infection can't be controlled.
These findings may lead to new treatment options in the medium term, because some TNF inhibiting drugs are already on the market.
The results of this Cluster cooperation were recently published in Nature Immunology:
Tumor necrosis factor impairs CD4+ T cell-mediated immune control in chronic viral infection; Nature Immunology; DOI: 10.1038/ni.3399
https://www.uni-bonn.de/Pressemitteilungen/043-2016
http://www.tum.de/en/about-tum/news/press-releases/short/article/32987/

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Cluster member Christian Kurts in-studio guest at Lokalzeit Bonn


March 04, 2016

 

Cluster member Christian Kurts is sharing his thoughts on the importance of the Leibniz Prize for high risk projects.
Watch the interview here:
WDR Mediathek

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Win prizes with your thesis (and some additional effort)!


February 29, 2016

 

If you finished your PhD in 2015, were awarded excellent grades and have eloquent German writing skills, you probably should apply for one of the following prizes:
1) "Deutscher Studienpreis" for research with outstanding social value.
More information can be found here: link
and
2) "Klaus Tschira Preis für verständliche Wissenschaft" for writing a popular science article in German about your research.
More information can be found here: link

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Kerstin Ludwig leads new Emmy Noether research group on craniofacial genomics


February 22, 2016

 

We congratulate Cluster member Dr. Kerstin Ludwig for her new Emmy Noether research group "Craniofacial genomics"! 
You can find more information on her research here
Press release: https://www.uni-bonn.de/Pressemitteilungen/030-2016

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The ImmunoSensation Blog goes multimedia!


February 15, 2016

 

Blog or Vlog?
With their Blog contribution "What is NLRP3 and why do we care?" four PhD students from the Institute of Innate Immunity (Bonn) found an alternative way to show their research.
Check it out here: http://www.immunosensation.de/blog/?p=1068

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Healthy male volunteers wanted for genetic study!


February 10, 2016

 

Healthy male volunteers wanted!
Study topic
"Einfluss genetischer Faktoren auf die Immunantwort unter Berücksichtigung parasitärer, parodontaler und nickelinduzierter Einflussfaktoren"
(Influence of genetic factors on the immune reaction under consideration of parasitical, parodontal and nickel-induced factors)
Participating institutes
Institute of Medical Microbiology, Immunology and Parasitology
Institute of Human Genetics
Polyclinic for Orthodontics
For more information visit http://probanden.jimdo.com/

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Watch out, female scientists: funding available


January 25, 2016

 


Fast Track: Excellence and Leadership Skills for Outstanding Women in Science
Fast Track, the top-flight, intensive education program of the Robert Bosch Stiftung, is offering 20 outstanding female postdocs an unrivaled opportunity.

Read more...

New „pme Familienservice“ login available


January 21, 2016

 

We like to point to the new „pme Familienservice“ login. Here you can find all relevant information you need if you want to use our cooperation with the “pme Familienservice”.For more information and/or the new password, please contact

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We proudly present: The Cluster Times


December 28, 2015

 

Dear future "Cluster Times" fan,
We are pleased to introduce Issue No. 1 of "The Cluster Times", the ImmunoSensation newsletter that will now be served regularly.
Enjoy reading!!

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DFG funded Research Training Group "Bo&MeRanG" goes online


December 16, 2015

 

We are happy to announce that the DFG funded Research Training Group "Bo&MeRanG" is now online.

Read more...

Prof. Frank Bradke receives Leibniz Prize 2016


December 11, 2015

 

Cluster member Prof. Dr. Frank Bradke (German Center for Neurodegenerative Diseases) receives the Leibniz Prize 2016 in recognition of his pathbreaking research in the area of regenerative neurobiology.

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Annkristin Heine receives Lisec-Artz award


December 02, 2015

 

Congratulations to Cluster member Dr. Annkristin Heine from the Institute of Experimental Immunology (IEI) & the Medical Clinic III who received the Lisec-Artz award for outstanding cancer research.

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Review Board Election 2015: Preliminary Election Result


November 27, 2015

 

We are happy to announce that three Cluster members have been elected as members of the DFG review boards for the 2016-2019 term! The DFG review boards scientifically evaluate proposal to fund research projects in their respective subject areas.  The

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Beate Henrichfreise erhält PHOENIX Pharmazie Wissenschaftspreis


November 13, 2015

 

Wir gratulieren Gruppenleiterin Dr. Beate Henrichfreise, die im vergangenen Monat den PHOENIX Pharmazie Wissenschaftspreis 2015 erhielt. Die Preise werden in den Kategorien Pharmakologie und Klinische Pharmazie, Pharmazeutische Biologie, Pharmazeutische Chemie sowie Pharmazeutische Technologie verliehen.

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Zeitschrift „forsch“ der Uni Bonn berichtet über ImmunoSensation-Blog


November 12, 2015

 


Die Zeitschrift „forsch“ der Rheinische Friedrich-Wilhelms-Universität Bonn berichtet in der Oktober 2015-Ausgabe über unseren Cluster-Blog:

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DFG funds new Research Training Groups: Christian Kurts is speaker of "Bo&MeRanG"


November 11, 2015

 

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing 16 new Research Training Groups to further support early career researchers in Germany. Four of the new groups will be International Research Training Groups (IRTG).We congratulate Cluster member Prof. Christian

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Cluster Science Days 2015: Pictures available


November 05, 2015

 

Dear Cluster members and associated scientists,
Impressions from the 3rd Cluster Science Days (Nov 2-3, 2015, BMZ1 Venusberg Campus) are now online. Please find all pictures following this link.

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Review Board Election 2015: Your vote for science!


October 28, 2015

 

Dear Cluster members,Elections for the members of the DFG review boards for the 2016-2019 term are upcoming! The DFG review boards scientifically evaluate proposal to fund research projects in their respective subject areas. 

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Anna-Maria Herzner was awarded the Paula Pitha Award


October 08, 2015

 

Congratulations to Anna-Maria Herzner, who was awarded the Paula Pitha Award to Best Abstracts on Interferon Research at the TOLL2015 Conference (http://www.toll2015.org), which took place in Marbeilla, Spain, September 30 - October 3, 2015. More than 400 Abstracts had been submitted. 

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Veit Hornung has been appointed Professor at the Gene Center in Munich


October 07, 2015

 

Veit Hornung has been appointed Professor for Immunobiochemistry at the Gene Center in Munich We would very cordially like to congratulate Prof. Veit Hornung, Cluster member and former director of the Institute of Molecular Medicine in Bonn, who has been appointed W3 Professor for

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ImmunoSensation Cluster Seminar by Prof. Hermona Soreq


October 06, 2015

 

We are happy to welcome Cluster member and cooperation partner Prof. Hermona Soreq from The Edmond and Lily Safra Center for Brain Sciences, Jerusalem: Speaker
Prof. Hermona Soreq
Professor of Molecular Neuroscience
The Edmond and Lily Safra Center for Brain Sciences,
JerusalemTopicFrom mice to

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ImmunoSensation Cluster Seminar by Prof. David Tarlinton


October 05, 2015

 



Speaker
Prof. David Tarlinton
Walter and Eliza Hall Institute of Medical Research,
Melbourne, AustraliaTopic
Controlling the Input and Output of Germinal Centers: Roles for Myb and PRMT1Date
October 05, 2015

Time

05:00

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Prof. Dr. Christoph Wilhelm - Ernennung zum Universitätsprofessor für Immunpathologie


September 29, 2015

 


Mit Wirkung vom 07.09.2015 wurde Herr Prof. Dr. Christoph Wilhelm zum Universitätsprofessor (W2) für das Fach "Immunpathologie (Exzellenzcluster)" ernannt.

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ImmunoSensation Cluster Seminar by PD Dr. Dieter Jenne


September 22, 2015

 



Speaker
PD. Dr. Dieter Jenne
Institute of Lung Biology and Disease,
Comprehensive Pneumology Center, Helmholtz Zentrum MünchenTopic
Elastases and related serine proteases of neutrophils: intensifiers of defense and destructionDate
September 22,

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7th International Symposium DAMPS and HMGB1 in Bonn


September 10, 2015 - September 12, 2015

 

The international HMGB1 group of scientists and the ImmunoSensation Cluster of Excellence in Bonn had the honour to host the 7th International Symposium on DAMPS and HMGB1, which took place September 10-12, 2015, at the BMZ in Bonn.

Find more information here www.damps-hmgb1.de

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ImmunoSensation Annual Report 2014 is now available


September 08, 2015

 

ImmunoSensation Annual Report 2014 is now available

We are happy to announce that the ImmunoSensation Annual Report 2014 is printed. To view and download the online-version, which is available on our website, please follow the link below:
http://www.immunosensation.de/fileadmin/user_upload/pdf/Annual_Report/150905_Jahresbericht_web_2014.pdf

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New publication by Martin Schlee and colleagues in Nature Immunology


September 08, 2015

 

The HI virus disguises its genetic material Researchers at the University of Bonn show how our body detects viruses and how the HI virus tries to protect itself

Researchers at

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ImmunoSensation Cluster Seminar by Prof. William Harnett


August 25, 2015

 



Speaker
Prof. William Harnett
University of StrathclydeTopic
The parasitic worm product ES-62: a starting point for novel anti-inflammatory drug developmentDate
August 25, 2015

Time

05:00 pm

Location
BMZ, lecture hall 1 (building

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New Cluster publication by Wolfgang Kastenmüller and colleagues


August 19, 2015

 

Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions

Read more...

New entries from the ImmunoSensation Blog team available


July 20, 2015

 

New entries from the ImmunoSensation Blog team availableFind the latest postings from the ImmunoSensation Blog team

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New Cluster publication in Immunity


July 15, 2015

 

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA

Read more...

Cluster goes Charity: Mary’s meals 2.0


July 09, 2015

 

Cluster goes Charity: Mary’s meals 2.0

The Cluster participated in the charity project „Mary’s meals“.
In the name of the Cluster Coordination Office we would like to thank you! This year we were able to donate 12 backpacks.

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New Blogarticle about the Students' Networking Meeting


June 21, 2015

 

The ImmunoSensation Blog team published a new article about the Students' Networking MeetingFind the latest postings from the ImmunoSensation Blog team

Read more...

New entries from the ImmunoSensation Blog team available


June 17, 2015

 

New entries from the ImmunoSensation Blog team availableFind the latest postings from the ImmunoSensation Blog team

Read more...

ImmunoSensation participates in open day at the Villa Hammerschmidt on June 14, 2015


June 14, 2015

 

ImmunoSensation participates in open day at the Villa Hammerschmidt on June 14, 2015

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pme holiday care for children available now


June 11, 2015

 

pme holiday care for children available now


The ImmunoSensation Cluster of Excellence still cooperates with the “pme Familienservice GmbH” and we are now able to provide “Holiday Care” and “Back-Up Care” nationwide.

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Reminder: The Cluster provides "Back-up Care" during Kita-strike


May 27, 2015

 

Cluster provides Holiday Care and Back-Up Days for children

Due to the ongoing Kita-strike we would like to remind you that the ImmunoSensation Cluster of Excellence cooperates with the “pme Familienservice GmbH” and is able to provide “Holiday Care” and “Back-Up Care” nationwide.

Read more...

The ImmunoSensation Blog goes online


May 27, 2015

 

ImmunoSensation has just launched its own science blog. The blog team reports on Cluster events, interviews experts on recent papers but also asks a bit more personal questions. Weekly updates will inform you about the most exciting things happening in the Cluster. The blog team consists of six PhD

Read more...

Leopoldina welcomes Prof. Christian Kurts as a new member


May 21, 2015

 

The German National Academy of Sciences Leopoldina welcomes Prof. Christian Kurts who became an elected member in 2014.
The press release can be found here.

Read more...

Prof. Veit Hornung is elected to EMBO membership


May 20, 2015

 

EMBO has announced Prof. Veit Hornung as one of 58 outstanding researchers in the field of life sciences that have been elected to its membership.

Read more...

Prof. Dr. Nicolas Wernert becomes new dean of the medical faculty


May 01, 2015

 

With the new term Prof. Dr. Nicolas Wernert became the dean of the medical faculty.
Contact details and more information can be found here.

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Inauguration of Prof. Michael Hoch as Rektor of the University of Bonn


April 29, 2015

 

Cluster member Prof. Michael Hoch was officially announced as Rector of the University of Bonn. Congratulations!

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Child care: Opening of the nursery school „Auf dem Hügel“


April 24, 2015

 

Official opening of the nursery school „Auf dem Hügel“  
 Places available for children from employees and students of the University of Bonn!
 Press Infomation University of Bonn

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Girls’ Day on April 23, 2015 at the ImmunoSensation Cluster of Excellence


April 23, 2015

 

For the second time the ImmunoSensation Cluster of Excellence joined the „Girls’ Day“. Five 14 to 15 year-old girls visited the Cluster at the University Hospital Bonn.

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Prof. Kolanus elected as executive Director of the LIMES Institute


April 23, 2015

 

On March 23, Prof. Waldemar Kolanus the vice speaker of the ImmunoSensation cluster of excellence, was officially elected as the new executive Director of the

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Kinderuni with Prof. E. Latz on April 20, 2015 "Das Abwehrsystem des Körpers: Die Polizei in Dir" for children 8-13 years old


April 20, 2015

 

“Kinderuni der Rheinischen Friedrich-Wilhelms- Universität Bonn” (in German)

Date

April 20, 201
5

Time

05:00 pm (c.t.)


LocationUniversity of Bonn

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ImmunoSensation Seminar by Dr. Emma Hamilton-Williams (The University of Queensland, Australia)


April 20, 2015

 

            Speaker
Dr. Emma Hamilton-Williams
Diamantina Institute, Translational Research Institut
The University of

Read more...

Women in Science Seminar Series: Dr. Manuela Schmidt (Max Planck Institute of Experimental Medicine, Göttingen)


April 20, 2015

 

            Speaker
Dr. Manuela Schmidt
Somatosensory Signaling
Max Planck Institute of Experimental Medicine, GöttingenTopic
Exploring the Molecular Signature of Mammalian Touch and Pain- Insights into Health and DiseaseDateApril 20,

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Prof. Veit Hornung received an ERC Grant for his project „Genetic Dissection of innate immune sensing and signaling” (GENESIS)


April 02, 2015

 

Two projects from the University of Bonn have been very successful and raised ERC (European Research Council) Consolidator Grants.One of them was Cluster Member Veit Hornung (Institute of Molecular Medicine, University of Bonn) who will get 1.9 Million Euro for his project „Genetic Dissection

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Mini-Symposium „Epigenetics and Chromatin Structure“, March 31, 2015 at LIMES


March 31, 2015

 

Mini-Symposium „Epigenetics and Chromatin Structure“, March 31, 2015 at the Life and Medical Sciences Institute (LIMES) in Bonn                                       

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Cluster Member Prof. Soreq will receive the Rappaport Prize for Excellence in Medical Research


March 02, 2015

 

Prof. Hermona Soreq (The Hebrew University of Jerusalem) will receive the Rappaport Prize for Excellence in Medical Research, together with Dr. Eran Elinav of Weizman Institute of Science. The Prize for Prof. Soreq's includes prize money of $60,000 "for her research on the neurotransmitter

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One-Day Seminar: Flow Cytometry in Immunology, February 24, 2015


February 24, 2015

 

If you are looking for new ideas and strategies or if you just want to refresh your knowledge about immunological methods in flow cytometry, consider to take part in a one day seminar “Flow Cytometry in Immunology” on the Campus Venusberg.Find more information

Read more...

New Cluster publication of Dagmar Wachten (caesar) and colleagues in eLife


January 20, 2015

 

Shedding light on fertility – control of sperm function by optogenetics
Scientists from the Center of Advanced European Studies and Research (caesar) in Bonn, an Institute of the Max Planck Society, have succeeded for the first time in controlling the function of sperm by optogenetics. They

Read more...

New Cluster publication of Dagmar Wachten (caesar) and colleagues in eLife


January 20, 2015

 

Shedding light on fertility – control of sperm function by optogenetics
Scientists from the Center of Advanced European Studies and Research (caesar) in Bonn, an Institute of the Max Planck Society, have succeeded for the first time in controlling the function of sperm by optogenetics. They

Read more...

Cluster Member Prof. Michael Hoch (LIMES) was elected Rector of the University of Bonn


December 11, 2014

 

     Press Release (in German) December 11, 2014 Press Release (in

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Cluster goes Charity 2.0: The Cluster participates in the project “Alte Schuhe – neues Leben” (old shoes – new life)


December 09, 2014

 

     
Due to the success of our last participation in the charity project “Mary’s meals” in June this year, we would like to ask you for your support and contribution again.

The Cluster aims to participate in the project called “Alte Schuhe – neues Leben” (old shoes –

Read more...

University of Bonn awarded Professor Charles Dinarello an honorary doctor's degree on November 22, 2014


November 22, 2014

 

Prof. Charles Dinarello from the Division of Infectious Diseases in Aurora (USA) and Radboud- University Nijjmegen (Netherlands) received an honorary doctor’s degree by the Medical Faculty of the University of Bonn for his achievements in immunology.

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Welcome Centre for International Researchers at University of Bonn - Service & Advice for international researchers


November 18, 2014

 

The Welcome Centre assists visiting professors and researchers (postdocs) who are planning a research stay at the University of Bonn as well as their host institutes.Find more information Read more...

Prize Winners of the ImmunoSensation's Cluster Science Days November 3 & 4, 2014


November 05, 2014

 

This year, the ImmunoSensation's Cluster Science Days on November 3 & 4 took place in the Biomedical Center at the University Hospital Bonn.During these two days 19 professors, 7 group leaders and 21 PhD students and young postdocs gave a short talk or a keynote lecture to present their

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Childcare available to scientists: Cooperation with Max & Mary Kindergarten


October 28, 2014

 

The ImmunoSensation Cluster of Excellence is glad to announce that we cooperate with the private preschool Max and Mary Kindergarten (Robert-Koch-Straße 94, 53127 Bonn, www.maxandmary.de).

We offer you financial support if you want

Read more...

New Cluster Publication of Cluster Members and their colleagues in Nature Communications


October 20, 2014

 

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

Cluster Members Prof. Holger Fröhlich, Prof. Markus Nöthen, Prof. Veit Hornung and the Cluster associated scientist Prof. Johannes Schumacher published together in Nature Communications, together with

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Leopoldina welcomes Prof. Frank Bradke as a new member


October 09, 2014

 

The German National Academy of Sciences Leopoldina welcomes Prof. Frank Bradke who became an elected member in 2014.The press release can be found

Read more...

ImmunoSensation Cluster of Excellence - Annual Report 2013


September 17, 2014

 

You can find ImmunoSensation's Annual Report 2013

Read more...

New Cluster publication of Cluster Speaker Prof. Gunther Hartmann and colleagues in Nature


August 11, 2014

 

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5’diphosphatesCluster Speaker Prof. Gunther Hartmann and Cluster member Dr. Winfried Barchet, together with an international team of researchers from the University of Bonn Hospital and the London Research Institute, have now

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Cluster members Prof. Veit Hornung and Prof. Eicke Latz are two highly cited researchers of the last decade


July 21, 2014

 

The media group "Thomson Reuters" published a list of the most frequently cited and therefore most influential scientists of the last decade.
Two of our cluster immunologists, Prof. Dr. Veit Hornung (Director of the Institute of Molecular Medicine, University of Bonn) and Prof. Dr. Eicke

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Cooperation with the “pme Familienservice GmbH” which provides “Holiday Care” and “Back-Up Care” for children nationwide.


July 18, 2014

 

The ImmunoSensation Cluster of Excellence is glad to announce that we cooperate with the “pme Familienservice GmbH” and we are able to provide “Holiday Care” and “Back-Up Care” nationwide.For more information, please see

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New Cluster Publication of Prof. Markus Nöthen and Prof. Michael Heneka (both University of Bonn) in "Nature Genetics"


July 08, 2014

 

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasiaIdiopathicachalasia is characterized by a failure of the lower esophageal sphincter to relax due to a loss of neurons in the myenteric plexus. This ultimately leads to

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New Cluster Publication of Cluster Member Prof. Eicke Latz and colleagues in "Nature Immunology"


June 23, 2014

 

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammationThe Cluster Members Prof. Eicke Latz, Prof. Wolfgang Kastenmüller and Dr. Ashraf Al-Amoudi published in Nature Immunology together with their Cluster teams as well as with cooperating institutions how microbes

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ImmunoSensation Cluster of Excellence supports women in science by MeTra Program


June 12, 2014

 

In a joint effort, the Cluster’s Young Investigator Support and the Gender Support offer the possibility to attend the mentoring and training program (MeTra) for female researchers at the University of Bonn.
MeTra is part of the Maria von Linden program that supports women in science, and is

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The ImmunoSensation Cluster participates in the "9th Night of Science" on May 22 & 23


May 23, 2014

 

        
We are proud to announce the Cluster’s participation at the "9. Bonner Wissenschaftsnacht" (9th Night of Science) on May 22 & 23.The Night of Science is a public event giving research institutions the possibility to present their research, and to

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"Meet-the-expert-event" with Prof. Christopher Workman (Center for Biological Sequence Analysis, Kongens Lyngby, DK)


May 23, 2014

 

        Within the framework of the lecture series on Systems Biology, Prof. Christopher Workman, Associate Professor at the Center for Biological Sequence Analysis, Kongens Lyngby, DK will present a talk entitled “Systems biology approaches for determining

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New Cluster Publication of Prof. U.B. Kaupp and Dr. D. Wachten (both caesar) in "EMBO Reports"


May 12, 2014

 

Directed action of endocrine disrupting chemicals on human sperm
The Cluster members Prof. Benjamin U. Kaupp and Dr. Dagmar Wachten (both caesar) published in "EMBO reports" together with their caesar colleagues and a cooperating Danish team how synthetic endocrine disrupting chemicals

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"Meet-the-expert-event" with Dr. Nir Yosef (University of Berkeley, USA)


May 09, 2014

 

Within the framework of the lecture series on Systems Biology, Dr. Nir YosefAssistant Professor at the Dept. of Electrical Engineering & Computer Science, Center for Computational Biology, University of Berkeley, USA will present a talk entitled “Reconstructing the Th17

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New Cluster Publication of Dagmar Wachten (caesar) and Prof. Michael Hoch (Limes)


March 31, 2014

 

"Murine Creld1 Controls Cardiac Development through Activation of Calcineurin/NFATc1 Signaling"                          
Cluster members Prof. Hoch, Elvira Mass, Anna Aschenbrenner and André Voelzmann (all LIMES)

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Girls' Day on March 27, 2014 at the ImmunoSensation Cluster of Excellence


March 27, 2014

 

For the first time the ImmunoSensation Cluster of Excellence joined the „Girls’ Day“ on March 27, 2014. Eight 11-15 year-old girls visited the Cluster at the University Hospital Bonn. After a brief introduction about the Cluster and its structure, the girls met Professor Regina Betz who told

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Free places at the nursery school „Auf dem Hügel- Endenich“ (University of Bonn)


March 21, 2014

 

The University of Bonn built a new nursery school in Bonn-Endenich („Auf dem Hügel- Endenich“) and it will open this year. There

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Cluster Member Andrea Ablasser received the Paul Ehrlich- und Ludwig Darmstaedter award


March 17, 2014

 

     Cluster Member Andrea Ablasser (Intitute of Clinical Chemistry & Clinical Pharmacology, University of Bonn) won the Paul Ehrlich- und Ludwig Darmstaedter award. She received the price from Nobel laureate Prof. Dr. Harald zur Hausen in St. Paul's Church (Frankfurt) on

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New Cluster Publication of Prof. Markus Nöthen and colleagues in "Nature Communications"


March 12, 2014

 

Genome-wide association study reveals two new risk loci for bipolar disorder

Cluster member Prof. Markus M. Nöthen (University Hospital Bonn) investigated in his new Nature communications article the genetic basis of bipolar disorder (BD) using genome-wide association studies (GWAS). In a great

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New cluster publication of Prof. Thomas Tüting and colleagues in "Nature"


February 28, 2014

 

               
Ultraviolet radiation-induced inflammation promotes angiotropism and metastasis in melanoma
The Cluster members Prof. Thomas Tüting, Prof. Michael Hölzel, Prof. Wolfgang Kastenmüller(all University Hospital Bonn), Prof. Waldemar

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New cluster publication of Prof. Joachim Schultze and colleagues in "Immunity"


February 17, 2014

 

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation  Cluster member Prof. J. Schultze from the Life & Medical Sciences Institute (LIMES) investigated the transcriptional program of macrophage activation and polarization. The analysis revealed a

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New cluster publication of Prof. Christian Kurts and colleagues in "Cell"


February 03, 2014

 

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected UroepitheliumThe recent published Cell paper of the cluster members Prof. Christian Kurts and Dr. Daniel Engel of the Institute of Experimental Immunology (IMMEI) deals with the functional specialization

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Interview with Prof. Gunther Hartmann on medica.de (World Forum for Medicine)


January 22, 2014

 

Cluster Speaker Gunther Hartmann (University Hospital Bonn) was interviewed by medica.de (World Forum for Medicine) about ImmunoSensation Cluster of Excellence.Here you can find the whole

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Prof. Eicke Latz raised ERC Consolidator Grant for "InflammAct" project


January 21, 2014

 

       Four projects from the University of Bonn have been very successful and raised an ERC (European Research Council) Consolidator Fund.One of them was Cluster Member Eicke Latz (Institute of Innate Immunity, University of Bonn) who will get 1.95 Million Euro

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Kinderuni with Prof. M. Heneka on January 20 "Learn and remember: From squirrels and immune cells" for children 8-12 years old


January 20, 2014

 

    What do squirrels and immune cells have in common? Both have to learn: the squirrels in order to find again their winter stocks and the immune cells to protect us from germs.How do these systems remember such things? You

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„Meet-the-expert-event“ with Dr. Sten Linnarsson (Karolinska Institute, Stockholm)


January 17, 2014

 

    
Within the framework of the new Lecture Series on Systems Biology, Dr. Sten Linnarsson, Karolinska Institute, Department of Medical Biochemistry and Biophysics, Stockholm, Sweden will present a talk entitled “Unbiased cell type discovery by large-scale quantitative

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How "good cholesterol" stops inflammation - New cluster publication in Nature Immunology


December 09, 2013

 

Cluster Members Eicke Latz and Joachim L. Schultze and their teams investigated how high-density lipoprotein (HDL) is responsible for down regulating the inflammatory reactions, via the activation of ATF3.Publication:

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New publication of Cluster Member Dagmar Wachten: CRIS, a novel regulator of male fertility.


December 05, 2013

 

New publication of cluster member Dr. Dagmar Wachten (caesar) about a novel player in male fertility.

CRIS—A Novel cAMP-Binding Protein Controlling Spermiogenesis and the Development of

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Third funding period of the SFB 704 granted by the DFG - Speaker: Prof. W. Kolanus, Co-Speaker Prof. C. Kurts


November 21, 2013

 

Collaborative Research Centre 704
Molecular Mechanisms and Chemical Modulation of Local Immune

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Dr. Andrea Ablasser and Prof. Veit Hornung received Pettenkofer Prize on November 7, 2013


November 08, 2013

 

Cluster Members Andrea Ablasser and Prof. Veit Hornung won the Pettenkofer Prize 2013. The Pettenkofer Prize is awarded every two years by the Pettenkofer Foundation, which is administered by the Social Services Department of the City of Munich. The prize is endowed with 5.000

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Prof. Bernd Fleischmann is a new Member of the ImmunoSensation Cluster of Excellence


November 06, 2013

 

Prof. Dr. med. (I) Bernd K. Fleischmann has become the 53rd member of the ImmunoSensation Cluster of Excellence.
As the Director of the Institute of Physiology I at the University of Bonn, Prof. Fleischmann is a renowned researcher in the field of molecular cardiovascular physiology. His group has

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