ImmunoSensation - the immune sensory system

1. Attenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model
Sumin Lee, Keiji Hirota, Verena Schuette, Takashi Fujita, Hiroki Kato
Biochem Biophys Res Commun . 2022 Nov 12
PMID: 36122455
2. Low TINAGL1 expression is a marker for poor prognosis in breast cancer
Akiko Kato, Naoto Kondo, Yumi Wanifuchi-Endo, Takashi Fujita, Tomoko Asano, Tomoka Hisada, Yasuaki Uemoto, Mitsuo Terada, Hiroyuki Kato, Masayuki Komura, Katsuhiro Okuda, Satoru Takahashi, Tatsuya Toyama
J Cancer Res Clin Oncol . 2022 Oct 14
PMID: 36229542
3. Activation of cytokine responses by Candida africana
Diletta Rosati, Mariolina Bruno, Frank van de Veerdonk, Jaap Ten Oever, Jacques F Meis, Mihai G Netea
Med Mycol . 2022 Oct 12
PMID: 36195329
4. Transcatheter Tricuspid Annulus Reconstruction: Compelling and Complex
Georg Nickenig, Atsushi Sugiura
JACC Cardiovasc Interv . 2022 Oct 10
PMID: 36202562
5. SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
Shovamayee Maharana, Stefanie Kretschmer, Susan Hunger, Xiao Yan, David Kuster, Sofia Traikov, Thomas Zillinger, Marc Gentzel, Shobha Elangovan, Padmanava Dasgupta, Nagaraja Chappidi, Nadja Lucas, Katharina Isabell Maser, Henrike Maatz, Alexander Rapp, Virginie Marchand, Young-Tae Chang, Yuri Motorin, Norbert Hubner, Gunther Hartmann, Anthony A Hyman, Simon Alberti, Min Ae Lee-Kirsch
Mol Cell . 2022 Oct 6;
PMID: 36150385
6. Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B
Johannes Oldenburg
N Engl J Med . 2022 Oct 6;
PMID: 36198186
7. Subcutaneous birch pollen allergen immunotherapy with a depigmented polymerized extract shows only sustained and long-term efficacy in a subgroup of monosensitized adults and adolescents with allergic rhinitis
Natalija Novak, Margitta Worm, Petra Staubach, Marek Jutel, Angelika Sager, Oliver Pfaar
Clin Transl Allergy . 2022 Oct 5;
PMID: 36225264
8. Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
Nina Kessler, Susanne F Viehmann, Calvin Krollmann, Karola Mai, Katharina M Kirschner, Hella Luksch, Prasanti Kotagiri, Alexander M C Böhner, Dennis Huugen, Carina C de Oliveira Mann, Simon Otten, Stefanie A I Weiss, Thomas Zillinger, Kristiyana Dobrikova, Dieter E Jenne, Rayk Behrendt, Andrea Ablasser, Eva Bartok, Gunther Hartmann, Karl-Peter Hopfner, Paul A Lyons, Peter Boor, Angela Rösen-Wolff, Lino L Teichmann, Peter Heeringa, Christian Kurts, Natalio Garbi
J Exp Med . 2022 Oct 3;
PMID: 35997679
9. Co-expression effect of LLGL2 and SLC7A5 to predict prognosis in ERα-positive breast cancer
Tomoka Hisada, Naoto Kondo, Yumi Wanifuchi-Endo, Satoshi Osaga, Takashi Fujita, Tomoko Asano, Yasuaki Uemoto, Sayaka Nishikawa, Yusuke Katagiri, Mitsuo Terada, Akiko Kato, Hiroshi Sugiura, Katsuhiro Okuda, Hiroyuki Kato, Masayuki Komura, Satoshi Morita, Satoru Takahashi, Tatsuya Toyama
Sci Rep . 2022 Oct 3;
PMID: 36192404
10. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas
Tobias Goschzik, Martin Mynarek, Evelyn Doerner, Alina Schenk, Isabel Spier, Monika Warmuth-Metz, Brigitte Bison, Denise Obrecht, Nina Struve, Rolf-Dieter Kortmann, Matthias Schmid, Stefan Aretz, Stefan Rutkowski, Torsten Pietsch
Acta Neuropathol . 2022 Oct 1.
PMID: 36181537
11. Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol
Elina Avraamidou, Moritz Nöthel, Melina Danisch, Laura Bindila, Susanne V Schmidt, Beat Lutz, Georg Nickenig, Julian Jehle
J Cardiovasc Transl Res . 2022 Sep 30
PMID: 36178662
12. Microfluidics for Neuronal Cell and Circuit Engineering
Rouhollah Habibey, Jesús Eduardo Rojo Arias, Johannes Striebel, Volker Busskamp
Chem Rev . 2022 Sep 28
PMID: 36070858
13. Clinical experience of switching patients with severe hemophilia to rVIII-SingleChain or rIX-FP
Johannes Oldenburg, Steven W Pipe, Maria Elisa Mancuso, Robert Klamroth, Abel Hassoun, Martin Olivieri, Georg Goldmann, Gili Kenet, Wolfgang Miesbach, Jolana Schmiedl, Inga Hegemann
Curr Med Res Opin . 2022 Sep 28
PMID: 36170120
14. Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV
Nadira Vadaq, Yue Zhang, Elise Meeder, Lisa Van de Wijer, Muhammad Hussein Gasem, Leo Ab Joosten, Mihai G Netea, Quirijn de Mast, Vasiliki Matzaraki, Arnt Schellekens, Jingyuan Fu, André Jam van der Ven
Int J Tryptophan Res . 2022 Sep 27
PMID: 36187510
15. Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease
Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, SYSCID Consortium, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel
Genome Med . 2022 Sep 24
PMID: 36153599
16. Analysis of associations between dietary patterns, genetic disposition, and cognitive function in data from UK Biobank
Christina-Alexandra Schulz, Leonie Weinhold, Matthias Schmid, Markus M Nöthen, Ute Nöthlings
Eur J Nutr . 2022 Sep 24
PMID: 36152054
17. Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial
Kerstin Mezger, Sabine Ebert, Hannah Elisa Muhle, Udo Zur Stadt, Arndt Borkhardt, Dagmar Dilloo, Jörg Faber, Tobias Feuchtinger, Thomas Imschweiler, Norbert Jorch, Arnulf Pekrun, Irene Schmid, Franziska Schramm, Martin Zimmermann, Martin A Horstmann, Gabriele Escherich
Pediatr Blood Cancer . 2022 Sep 21
PMID: 36129234
18. How location and cellular signaling combine to activate the NLRP3 inflammasome
Anil Akbal, Alesja Dernst, Marta Lovotti, Matthew S J Mangan, Róisín M McManus, Eicke Latz
Cell Mol Immunol . 2022 Sep 20
PMID: 36127465
19. Correction: PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis
Wenjie Zuo, Mai Wakimoto, Noriyasu Kozaiwa, Yutaro Shirasaka, Seong-Wook Oh, Shiori Fujiwara, Hitoshi Miyachi, Amane Kogure, Hiroki Kato, Takashi Fujita
Cell Death Dis . 2022 Sep 19
PMID: 36123340
20. The serotonin receptor 3E variant is a risk factor for female IBS-D
Nikola Fritz, Sabrina Berens, Yuanjun Dong, Cristina Martínez, Stefanie Schmitteckert, Lesley A Houghton, Miriam Goebel-Stengel, Verena Wahl, Maria Kabisch, Dorothea Götze, Mauro D'Amato, Tenghao Zheng, Ralph Röth, Hubert Mönnikes, Jonas Tesarz, Felicitas Engel, Annika Gauss, Martin Raithel, Viola Andresen, Jutta Keller, Thomas Frieling, Christian Pehl, Christoph Stein-Thöringer, Gerard Clarke, Paul J Kennedy, John F Cryan, Timothy G Dinan, Eamonn M M Quigley, Robin Spiller, Caroll Beltrán, Ana María Madrid, Verónica Torres, Emeran A Mayer, Gregory Sayuk, Maria Gazouli, George Karamanolis, Mariona Bustamante, Xavier Estivil, Raquel Rabionet, Per Hoffmann, Markus M Nöthen, Stefanie Heilmann-Heimbach, Börge Schmidt, André Franke, Wolfgang Lieb, Wolfgang Herzog, Guy Boeckxstaens, Mira M Wouters, Magnus Simrén, Gudrun A Rappold, Maria Vicario, Javier Santos, Rainer Schaefert, Justo Lorenzo-Bermejo, Beate Niesler
J Mol Med (Berl) . 2022 Sep 19
PMID: 36121467
21. Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ regulatory T cells
Janine Becker-Gotot, Mirjam Meissner, Vadim Kotov, Blanca Jurado-Mestre, Andrea Maione, Andreas Pannek, Thilo Albert, Chrystel Flores, Frank A Schildberg, Paul A Gleeson, Birgit M Reipert, Johannes Oldenburg, Christian Kurts
J Clin Invest . 2022 Sep 15
PMID: 36107620
22. Next-generation phenotyping contributing to the identification of a 4.7 kb deletion in KANSL1 causing Koolen-de Vries Syndrome
Fabian Brand, Aswinkumar Vijayananth, Tzung-Chien Hsieh, Axel Schmidt, Sophia Peters, Elisabeth Mangold, Kirsten Cremer, Tim Bender, Sugirthan Sivalingam, Hela Hundertmark, Alexej Knaus, Hartmut Engels, Peter M Krawitz, Claudia Perne
Hum Mutat . 2022 Sep 14
PMID: 36104871
23. Untreated bleeds in people with hemophilia A in a noninterventional study and intrapatient comparison after initiating emicizumab in HAVEN 1-3
Michael U Callaghan, Elina Asikanius, Michaela Lehle, Johannes Oldenburg, Johnny Mahlangu, Marianne Uguen, Sammy Chebon, Rebecca Kruse-Jarres, Víctor Jiménez-Yuste, Midori Shima, Peter Trask, Christine L Kempton, Craig M Kessler, Gallia G Levy, Flora Peyvandi
Res Pract Thromb Haemost . 2022 Sep 13
PMID: 36171959
24. Microbiological Trends and Antibiotic Susceptibility Patterns in Patients with Periprosthetic Joint Infection of the Hip or Knee over 6 Years
Frank Sebastian Fröschen, Thomas Martin Randau, Alexander Franz, Ernst Molitor, Achim Hoerauf, Gunnar Thorben Rembert Hischebeth
Antibiotics (Basel) . 2022 Sep 13
PMID: 36140023
25. Androgen Receptor Splice Variants Contribute to the Upregulation of DNA Repair in Prostate Cancer
Yuri Tolkach, Anika Kremer, Gábor Lotz, Matthias Schmid, Thomas Mayr, Sarah Förster, Stephan Garbe, Sana Hosni, Marcus V Cronauer, Ildikó Kocsmár, Éva Kocsmár, Péter Riesz, Abdullah Alajati, Manuel Ritter, Jörg Ellinger, Carsten-Henning Ohlmann, Glen Kristiansen
Cancers (Basel) . 2022 Sep 13
PMID: 36139600
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