ImmunoSensation - the immune sensory system

2601. Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP
Nature. 2013 May 30.
PMID: 23722159
2602. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Ablasser A, Goldeck M, Cavlar T, Deimling T, Witte G, Röhl I, Hopfner KP, Ludwig J, Hornung V
Nature. 2013 May 30.
PMID: 23722158
2603. Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.
Lange CM, Miki D, Ochi H, Nischalke HD, Bojunga J, Bibert S, Morikawa K, Gouttenoire J, Cerny A, Dufour JF, Gorgievski-Hrisoho M, Heim MH, Malinverni R, Müllhaupt B, Negro F, Semela D, Kutalik Z, Müller T, Spengler U, Berg T, Chayama K, Moradpour D, Bochud PY, ,
PLoS One. 2013 May 29.
PMID: 23734184
2604. Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.
Lämmermann T, Afonso PV, Angermann BR, Wang JM, Kastenmüller W, Parent CA, Germain RN
Nature. 2013 May 26.
PMID: 23708969
2605. Activation and regulation of the inflammasomes.
Latz E, Xiao TS, Stutz A
Nat Rev Immunol. 2013 May 24.
PMID: 23702978
2606. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.
Schlitzer A, McGovern N, Teo P, Zelante T, Atarashi K, Low D, Ho AW, See P, Shin A, Wasan PS, Hoeffel G, Malleret B, Heiseke A, Chew S, Jardine L, Purvis HA, Hilkens CM, Tam J, Poidinger M, Stanley ER, Krug AB, Renia L, Sivasankar B, Ng LG, Collin M, Ricciardi-Castagnoli P, Honda K, Haniffa M, Ginhoux F
Immunity. 2013 May 23.
PMID: 23706669
2607. Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays.
Gaebler A, Milan R, Straub L, Hoelper D, Kuerschner L, Thiele C
J Lipid Res. 2013 May 23.
PMID: 23709689
2608. The future of immunoimaging--deeper, bigger, more precise, and definitively more colorful.
Tang J, van Panhuys N, Kastenmüller W, Germain RN
Eur J Immunol. 2013 May 18.
PMID: 23568494
2609. Of inflammasomes and pathogens--sensing of microbes by the inflammasome.
Bauernfeind F, Hornung V
EMBO Mol Med. 2013 May 13.
PMID: 23666718
2610. Impaired CD4⁺ T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients.
Glässner A, Eisenhardt M, Kokordelis P, Krämer B, Wolter F, Nischalke HD, Boesecke C, Sauerbruch T, Rockstroh JK, Spengler U, Nattermann J
J Hepatol. 2013 May 9.
PMID: 23665286
2611. T-cell-derived, but not B-cell-derived, IL-10 suppresses antigen-specific T-cell responses in Litomosoides sigmodontis-infected mice.
Haben I, Hartmann W, Specht S, Hoerauf A, Roers A, Müller W, Breloer M
Eur J Immunol. 2013 May 8.
PMID: 23529858
2612. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ
Cell. 2013 May 3.
PMID: 23647843
2613. Siglec-h on activated microglia for recognition and engulfment of glioma cells.
Kopatz J, Beutner C, Welle K, Bodea LG, Reinhardt J, Claude J, Linnartz-Gerlach B, Neumann H
Glia. 2013 Apr 30.
PMID: 23633299
2614. RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.
Hagmann CA, Herzner AM, Abdullah Z, Zillinger T, Jakobs C, Schuberth C, Coch C, Higgins PG, Wisplinghoff H, Barchet W, Hornung V, Hartmann G, Schlee M
PLoS One. 2013 Apr 30.
PMID: 23653683
2615. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.
Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI
Alzheimers Res Ther. 2013 Apr 29.
PMID: 23634965
2616. High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.
Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Hölter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Garfinkel B, Orly J, Ovcharenko I, Bustin M
J Biol Chem. 2013 Apr 24.
PMID: 23620591
2617. Role of tachykinin 1 and 4 gene-derived neuropeptides and the neurokinin 1 receptor in adjuvant-induced chronic arthritis of the mouse.
Borbély E, Hajna Z, Sándor K, Kereskai L, Tóth I, Pintér E, Nagy P, Szolcsányi J, Quinn J, Zimmer A, Stewart J, Paige C, Berger A, Helyes Z
PLoS One. 2013 Apr 23.
PMID: 23626716
2618. Intrahepatic IL-8 producing Foxp3⁺CD4⁺ regulatory T cells and fibrogenesis in chronic hepatitis C.
Langhans B, Krämer B, Louis M, Nischalke HD, Hüneburg R, Staratschek-Jox A, Odenthal M, Manekeller S, Schepke M, Kalff J, Fischer HP, Schultze JL, Spengler U
J Hepatol. 2013 Apr 23.
PMID: 23624000
2619. Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT
Nat Chem Biol. 2013 Apr 21.
PMID: 23603659
2620. Species-specific detection of the antiviral small-molecule compound CMA by STING.
Cavlar T, Deimling T, Ablasser A, Hopfner KP, Hornung V
EMBO J. 2013 Apr 19.
PMID: 23604073
2621. A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice.
Li K, Fichna J, Schicho R, Saur D, Bashashati M, Mackie K, Li Y, Zimmer A, Göke B, Sharkey KA, Storr M
Neuropharmacology. 2013 Apr 18.
PMID: 23603203
2622. CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection.
Suppiah V, Armstrong NJ, O'Connor KS, Berg T, Weltman M, Abate ML, Spengler U, Bassendine M, Dore GJ, Irving WL, Powell E, Nattermann J, Mueller T, Riordan S, Stewart GJ, George J, Booth DR, Ahlenstiel G,
Genes Immun. 2013 Apr 18.
PMID: 23594959
2623. The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain.
Bader R, Sarraf-Zadeh L, Peters M, Moderau N, Stocker H, Köhler K, Pankratz MJ, Hafen E
J Cell Sci. 2013 Apr 16.
PMID: 23591813
2624. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA
Nat Immunol. 2013 Apr 14.
PMID: 23584070
2625. Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.
Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, Lutz B, Tüting T
J Immunol. 2013 Apr 12.
PMID: 23585676