ImmunoSensation - the immune sensory system

276. The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.
Cavaliere F, Fornarelli A, Bertan F, Russo R, Marsal-Cots A, Morrone LA, Adornetto A, Corasaniti MT, Bano D, Bagetta G, Nicotera P
Sci Rep. 2019 Mar 19.
PMID: 30890728
277. Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.
Salvagno C, Ciampricotti M, Tuit S, Hau CS, van Weverwijk A, Coffelt SB, Kersten K, Vrijland K, Kos K, Ulas T, Song JY, Ooi CH, Rüttinger D, Cassier PA, Jonkers J, Schultze JL, Ries CH, de Visser KE
Nat Cell Biol. 2019 Mar 18.
PMID: 30886344
278. Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.
Puelles VG, Fleck D, Ortz L, Papadouri S, Strieder T, Böhner AMC, van der Wolde JW, Vogt M, Saritas T, Kuppe C, Fuss A, Menzel S, Klinkhammer BM, Müller-Newen G, Heymann F, Decker L, Braun F, Kretz O, Huber TB, Susaki EA, Ueda HR, Boor P, Floege J, Kramann R, Kurts C, Bertram JF, Spehr M, Nikolic-Paterson DJ, Moeller MJ
Kidney Int. 2019 Mar 15.
PMID: 31155155
279. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.
Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F
Science. 2019 Mar 15.
PMID: 30872492
280. Preliminary results of biodistribution and dosimetric analysis of [Ga]Ga-DOTA: a new zoledronate-based bisphosphonate for PET/CT diagnosis of bone diseases.
Khawar A, Eppard E, Roesch F, Ahmadzadehfar H, Kürpig S, Meisenheimer M, Gaertner FC, Essler M, Bundschuh RA
Ann Nucl Med. 2019 Mar 15.
PMID: 30877560
281. Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice.
Thiem K, Hoeke G, van den Berg S, Hijmans A, Jacobs CWM, Zhou E, Mol IM, Mouktaroudi M, Bussink J, Kanneganti TD, Lutgens E, Stienstra R, Tack CJ, Netea MG, Rensen PCN, Berbée JFP, van Diepen JA
Sci Rep. 2019 Mar 13.
PMID: 30867470
282. Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes.
van der Poel M, Ulas T, Mizee MR, Hsiao CC, Miedema SSM, Adelia , Schuurman KG, Helder B, Tas SW, Schultze JL, Hamann J, Huitinga I
Nat Commun. 2019 Mar 13.
PMID: 30867424
283. Preclinical development of an oral anti- macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.
Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA
Sci Transl Med. 2019 Mar 13.
PMID: 30867321
284. Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O, , Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA
Front Neurosci. 2019 Mar 13.
PMID: 30930738
285. Brief report - Telomere length is a poor biomarker to predict 1-year mortality or cardiovascular comorbidity in patients with transcatheter aortic valve replacement.
Steinmetz M, Schmitter C, Radecke T, Stundl A, Nickenig G, Schaefer C, Schahab N, Vasa-Nicotera M, Sinning JM
PLoS One. 2019 Mar 12.
PMID: 30861019
286. Sleep-Disordered Breathing in Hospitalized Geriatric Patients with Mild Dementia and Its Association with Cognition, Emotion and Mobility.
Gronewold J, Haensel R, Kleinschnitz C, Frohnhofen H, Hermann DM
Int J Environ Res Public Health. 2019 Mar 9.
PMID: 30857293
287. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression.
Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT
Mol Neurobiol. 2019 Mar 9.
PMID: 30852796
288. COAGULATION FACTOR XIIIA-INHIBITOR TRIDEGIN: ON THE ROLE OF DISULFIDE BONDS FOR FOLDING, STABILITY, AND FUNCTION.
Bäuml CA, Schmitz T, Paul George AA, Sudarsanam M, Hardes K, Steinmetzer T, Holle LA, Wolberg AS, Pötzsch B, Oldenburg J, Biswas A, Imhof D
J Med Chem. 2019 Mar 9.
PMID: 30852892
289. Tracking the brain in myotonic dystrophies: A 5-year longitudinal follow-up study.
Gliem C, Minnerop M, Roeske S, Gärtner H, Schoene-Bake JC, Adler S, Witt JA, Hoffstaedter F, Schneider-Gold C, Betz RC, Helmstaedter C, Tittgemeyer M, Amunts K, Klockgether T, Weber B, Kornblum C
PLoS One. 2019 Mar 7.
PMID: 30845252
290. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.
Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, Lin CY, Kwiatkowski N, Gray NS
Cell Chem Biol. 2019 Mar 6.
PMID: 30905681
291. Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion.
Jux B, Gosejacob D, Tolksdorf F, Mandel C, Rieck M, Namislo A, Pfeifer A, Kolanus W
Sci Rep. 2019 Mar 5.
PMID: 30837656
292. Accuracy of Pretransplant Imaging Diagnostic for Hepatocellular Carcinoma: A Retrospective German Multicenter Study.
Herden U, Schoening W, Pratschke J, Manekeller S, Paul A, Linke R, Lorf T, Lehner F, Braun F, Stippel DL, Sucher R, Schmidt H, Strassburg CP, Guba M, van Rosmalen M, Rogiers X, Samuel U, Schön GM, Nashan B
Can J Gastroenterol Hepatol. 2019 Mar 5.
PMID: 30949459
293. Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma.
Chattopadhyay S, Thomsen H, Yadav P, da Silva Filho MI, Weinhold N, Nöthen MM, Hoffman P, Bertsch U, Huhn S, Morgan GJ, Goldschmidt H, Houlston R, Hemminki K, Försti A
Commun Biol. 2019 Mar 4.
PMID: 30854481
294. The role of checkpoint blockade after allogeneic stem cell transplantation in diseases other than Hodgkin's Lymphoma.
Holderried TAW, Fraccaroli A, Schumacher M, Heine A, Brossart P, Stelljes M, Klobuch S, Kröger N, Apostolova P, Finke J, Zeiser R, Heinicke T, Bornhäuser M, von Bergwelt-Baildon M, Tischer J, Wolf D
Bone Marrow Transplant. 2019 Mar 4.
PMID: 30833743
295. EF24 Suppresses Cholangiocellular Carcinoma Progression, Inhibits STAT3 Phosphorylation, and Induces Apoptosis via ROS-Mediated Oxidative Stress.
Bisht S, Nolting J, Wenzel J, Brossart P, Feldmann G
J Oncol. 2019 Mar 4.
PMID: 30949204
296. Kinetic and photonic techniques to study chemotactic signaling in sea urchin sperm.
Hamzeh H, Alvarez L, Strünker T, Kierzek M, Brenker C, Deal PE, Miller EW, Seifert R, Kaupp UB
Methods Cell Biol. 2019 Mar 4.
PMID: 30948028
297. DAMPening sterile inflammation of the kidney.
Meissner M, Viehmann SF, Kurts C
Kidney Int. 2019 Mar 1.
PMID: 30784655
298. Clinicopathological, immune and molecular correlates of PD-L2 methylation in gastric adenocarcinomas.
Lingohr P, Dohmen J, Semaan A, Branchi V, Dietrich J, Bootz F, Kalff JC, Matthaei H, Dietrich D
Epigenomics. 2019 Mar 1.
PMID: 30821175
299. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.
Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luðvigsson P, Sæmundsen E, Thorarensen Ó, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM,
Am J Psychiatry. 2019 Mar 1.
PMID: 30818990
300. Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
von Geldern TW, Morton HE, Clark RF, Brown BS, Johnston KL, Ford L, Specht S, Carr RA, Stolarik DF, Ma J, Rieser MJ, Struever D, Frohberger SJ, Koschel M, Ehrens A, Turner JD, Hübner MP, Hoerauf A, Taylor MJ, Ward SA, Marsh K, Kempf DJ
PLoS Negl Trop Dis. 2019 Feb 28.
PMID: 30818326