ImmunoSensation - the immune sensory system

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Clin Infect Dis. 2012 May 18.

Doxycycline improves filarial lymphedema independent of active filarial infection: a randomized controlled trial.

Mand S, Debrah AY, Klarmann U, Batsa L, Marfo-Debrekyei Y, Kwarteng A, Specht S, Belda-Domene A, Fimmers R, Taylor M, Adjei O, Hoerauf A

The aim of this study was to determine whether improvement of filarial lymphedema (LE) by doxycycline is restricted to patients with ongoing infection (positive for circulating filarial antigen [CFA]), or whether the majority of CFA-negative patients with LE would also show a reduction in LE severity.

PMID: 22610930