ImmunoSensation - the immune sensory system

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BMC Bioinformatics. 2020 Apr 16.

PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data.

Lemsara A, Ouadfel S, Fröhlich H

Recent years have witnessed an increasing interest in multi-omics data, because these data allow for better understanding complex diseases such as cancer on a molecular system level. In addition, multi-omics data increase the chance to robustly identify molecular patient sub-groups and hence open the door towards a better personalized treatment of diseases. Several methods have been proposed for unsupervised clustering of multi-omics data. However, a number of challenges remain, such as the magnitude of features and the large difference in dimensionality across different omics data sources.

PMID: 32299344