ImmunoSensation - the immune sensory system

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Immunity. 2012 Dec 19.

Retroviral danger from within: TLR7 is in control.

Mankan AK, Hornung V

In this issue of Immunity, Yu et al. (2012) outline a fascinating model in which TLR7-mediated antibody production acts as a dominant immunosurveillance mechanism against endogenous retroviruses (ERVs), with additional support of TLR3 and TLR9 that function to prevent ERV-mediated malignancy.

PMID: 23159222