SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Nature communications
View this publicationDepartment of Psychiatry and Psychotherapy
Venusberg-Campus 1 53127 Bonn
We are interested in understanding the cellular and molecular mechanisms of psychological stress on the brain and behavior, and how stress effects can be modulated by exercise and diet. We combine behavioral and genetic animal models with in vivo imaging of neurons and microglia to understand their structural and functional stress response. Endocrine and molecular changes are assessed in blood and cerebrospinal fluid to identify translational markers of individual vulnerability to stress.
