Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
The Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Friedrich-Wilhelms-University Bonn invites applications for a
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
We are seeking a highly motivated postdoctoral fellow to conduct research on the fundamental aspects of metabolic regulation of the immune system. The Project aims to understand how metabolites shape the biology and metabolism of tissue-resident immune cells (e.g. T cells, innate lymphoid cells (ILC)) in health and disease. The work builds on recent findings of the lab (Karagiannis et al. Nature 2022, Theodorou et al. BioRxiv 2024, Wientjens et al. Immunity 2025,) and is focused on studying how different diets (e.g. highfat diet, ketogenic diets) but also fasting modulate the immune response. The aim is to gain knowledge that could be applied to better understand and treat diseases such as obesity, chronic inflammation and infections. To translate findings to human patients, the project will leverage established collaborations with clinicians. The candidate will have the opportunity to obtain additional external funding and develop an independent research program during the postdoctoral training. We are looking for an enthusiastic scientist with a desire to work on a challenging and rewarding project as part of a friendly and supportive team. Applicants with Ph.D. degree and graduate students expecting to receive the degree within six months will be considered. The ideal candidate will have a background in immunology, tissue biology or cellular metabolism. Experience in working with animal models, cell isolations from tissues (lung, intestine), human tissue samples, multi-parameter flow cytometry, molecular biology and fluorescence imaging will be preferred. We offer an interdisciplinary research environment that fosters innovation and collaboration and are committed to training and career development of the next generation of scientists. The position is available for an initial period of three years with the possibility of extension.
We offer:
• The salary will be according to the German salary scale TV-L (EG 13, 100%)
• To work in a motivated team in a thriving research environment
• Attractive conditions and benefits, an interdisciplinary research institution that fosters innovation and collaboration and are committed to training and career development of the next generation of scientists
• Responsible and versatile: a job with a lot of creative freedom in a collegial team
• Flexible for families: flexible working time models, the option of a place in the company daycare center and offers for those returning from parental leave
• Provision for later: company pension scheme
• Clever to work: Possibility of an interest-free loan to buy an e-bike
• Tailor-made education: Subsidized further education and training
• Systematic start: Structured induction
• Healthy at work: Numerous health promotion offers, free membership in UKBfit
• Employer benefits: preferential offers for employees (corporate benefits)
The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome.
Applications should include a cover letter, CV and names and addresses of three referees and be send by e-mail until April 15th 2026 to
Prof. Christoph Wilhelm
Institute of Clinical Chemistry and Clinical Pharmacology
University Hospital Bonn
Venusberg-Campus 1
53127 Bonn, Germany
E-Mail: christoph.wilhelm@uni-bonn.de
Webpage: https://www.ukbonn.de/en/icccp/research/wilhelm-group/
PhD position – Dietary regulation of immune cells
The Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Friedrich-Wilhelms-University Bonn invites applications for a
PhD position – Dietary regulation of immune cells
The position is available for an initial period of three years, with the possibility of extension.
We are seeking a highly motivated candidate to fill a Ph.D. student position in dietary immunology in the research group of Christoph Wilhelm at the University Hospital Bonn (UKB), University of Bonn. Dietary immunology is an emerging field that investigates how dietary compounds and metabolites regulate the immune system. The project will investigate how diets (e.g. high-fat diet, ketogenic diets) and dietary components drive or reverse inflammation and includes the analysis of metabolic pathways controlling tissue resident immune cells such as T cells and innate lymphoid cells (ILC) (Karagiannis et al. Nature 2022, Theodorou et al. BioRxiv 2024, Wientjens et al. Immunity 2025). To investigate these processes the candidate will use mouse models, transcriptomics, classical immunological methods but also cutting-edge technologies, such as imaging flow cytometry, metabolomics, proteomics and extracellular flux analysis. In addition, the project has potential to utilize links with clinicians to translate findings to human patients. The overall aim is to identify novel dietary intervention strategies that are effective to reverse inflammation in diabetes and to treat chronic inflammation. Candidates with experience in cellular immunology, molecular cell biology or biochemistry are specifically encouraged to apply.
We offer:
• To work in a motivated team in a thriving research environment
• Attractive conditions and benefits, an interdisciplinary research institution that fosters innovation and collaboration and are committed to training and career development of the next generation of scientists
• Responsible and versatile: a job with a lot of creative freedom in a collegial team
• Flexible for families: flexible working time models, the option of a place in the company daycare center and offers for those returning from parental leave
• Provision for later: company pension scheme
• Clever to work: Possibility of an interest-free loan to buy an e-bike
• Tailor-made education: Subsidized further education and training
• Systematic start: Structured induction
• Healthy at work: Numerous health promotion offers, free membership in UKBfit
• Employer benefits: preferential offers for employees (corporate benefits)
The University of Bonn is committed to diversity and equal opportunity. It is certified as a familyfriendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome.
Applications should include a cover letter, CV, certificates, and names and addresses of two referees and be send by e-mail in a single PDF file until April 15th 2026 to:
Prof. Christoph Wilhelm
Institute of Clinical Chemistry and Clinical Pharmacology
University Hospital Bonn
Venusberg-Campus 1
53127 Bonn, Germany
E-Mail: christoph.wilhelm@uni-bonn.de
Webpage: https://www.ukbonn.de/en/icccp/research/wilhelm-group/
Laboratory Technician / Research Assistant (m/w/d) – Immunology
Institute: Institute of Molecular Medicine and Experimental Immunology (IMMEI) at the Medical Faculty Campus, University Hospital Bonn
Principle Investigator: Prof. Dr. Zeinab Abdullah
Position: Part time or full time (38.5 hrs/week)
Research Environment:
IMMEI, located at the Medical Faculty Campus of Bonn University Clinic, provides an exceptional environment for cutting-edge research. Our state-of-the-art facilities offer a platform for collaboration and innovation. The working group is led by Prof. Dr. Zeinab Abdullah (https://www.immei.de/research/zeinab-abdullah-laboratory), who has substantial experience and expertise in the field. IMMEI is comprised of 6 working groups and approx. 30 scientific and non-scientific staff (www.iei-bonn.de). AG Abdullah primarily studies chronic liver inflammation and its impact on anti-viral immune responses and tissue regeneration. The group utilises a diverse mixture of in vitro and in vivo methodologies to perform basic and applied immunological research. This position will be based within the AG Abdullah working group but you will be integrated and expected to work as part of the larger IMMEI research infrastructure.
Responsibilities:
- Work with transgenic mice (Genotyping, husbandry, organ processing, injections)
- Support scientists with experiments
- Help in the technical training of PhD and Masters students
- Cell culture
- Establishment of SOPs and maintenance of core lab resources
- Perform flow cytometric profiling of immune populations
Required Qualifications:
- Completed vocational training (BTA, MTA, CTA, or equivalent) or a Bachelor’s or Master’s degree in biology, biochemistry, immunology, or a related life science field. PhD holders are not eligible for this position.
- Hands-on flow cytometry experience, including sample acquisition, and data analysis
- Practical mouse handling experience, including in vivo injection techniques (I.V., S.C.) and organ processing
- FELASA B certification (or equivalent) for animal work, or willingness to obtain it
- Proficient in mammalian cell culture
- Standard molecular biology techniques (PCR, gel electrophoresis, etc.)
- Fluent German (written and spoken) – required for daily lab operations and regulatory documentation
- Good working English (written and spoken)
Desired Qualifications (not mandatory but preferred):
- Experience with mouse colony maintenance
- Experience with processing and handling of human samples
- Familiarity with in vitro immunological assays
We Offer:
- Competitive salary according to the German salary scale TV-L.
- Responsibility, variety, and flexibility in job scope
- Initial one-year project associated contract with the option to extend
- Family-friendly flexible working hours
- Occupational pension scheme
- Dynamic working environment
- Extensive training opportunities
How to Apply:
Submit a single PDF labelled “TA_position_[YourLastName]” containing:
- Cover letter
- Academic transcripts
- CV (short 2-4 pages)
- Contact information for two referees
Email this document to Prof. Zeinab Abdullah & Dr. Dillon Corvino (immei.abdullah.lab@gmail.com) with the subject “TA Application [YourLastName]”
Deadline: Rolling – position open until filled. Early applications encouraged.
Start date: Negotiable, preference for earliest availability.
Diversity and Equal Opportunity:
The University of Bonn is committed to diversity and equal opportunity irrespective of gender, ethnicity, age, nationality, religion, disability, etc. As such, applications will be assessed in accordance with the Landesgleichstellungsgesetz (State Equality Act).
Postdoctoral researcher position in Spatial Immunology (m/f/d)
The Schlitzer Lab is seeking a highly motivated postdoc to investigate the relationship among intratissular localization, cellular function, and the ontogeny of myeloid cells. Starting at the earliest possible date, this position is initially for 3 years and is integrated into the Cluster of Excellence Immunosensation3 and the Immunosensation3 spatial biology hub at the University of Bonn.
The Schlitzer Lab at the Life and Medical Sciences Institute utilizes cuttingedge spatial proteomics and transcriptomics to unravel novel mechanisms and regulatory circuits during the functional specialization and development of myeloid cells.
Postdoctoral researcher position in Spatial Immunology (100%, TVL13)
Your profile:
• University degree (PhD) in biomedical sciences, biology, bioinformatics, or a similar subject
• Strong background in immunology and/or computational biology
• Knowledge and experience in microscopy and/or spatial biology approaches
• Knowledge of flow cytometry
• Animal handling skills
• strong background in biology, preferable immunology
• Knowledge of the programming language R & Phyton
• excellent command of the English language
• motivated, flexible, team oriented and interested in continued professional development.
We offer:
• a varied and challenging position in a thriving academic environment
• access to state-of-the-art spatial biology methods
• embedding with an established cluster of excellence in Immunology
• a fully established bioinformatics department
• a professional career development program
• participation in the university-wide pension system (VBL)
• access to the extensive university sports program
• a salary based on the 13 TV-L scale
The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university and aims to increase the proportion of women employed in areas where women are underrepresented and to promote their careers. To that end, it urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable candidates with a certified disability or equivalent status are particularly welcome.
If you are interested in (filling) the position, please send your complete application documents by 31.03.2026 to andreas.schlitzer@uni-bonn.de with the application code Spatial/Bonn/Schlitzer. Before sending your application, please combine and convert all of your documents into one PDF file. For further information, please contact Andreas Schlitzer (Tel.: 0228/7383725).
Technical Assistant (MTA) (m/f/d)
In der Klinik für Neuroimmunologie am Universitätsklinikum Bonn ist zum nächstmöglichen
Zeitpunkt folgende Stelle in Vollzeit (38,5 Std./Woche) oder Teilzeit unbefristet zu besetzen:
Technische Assistenz - Biologielaborant*in (m/w/d)
In unserem Forschungslabor am Deutschen Zentrum für Neurodegenerative Erkrankungen (DZNE) unter der Leitung von Prof. Anne-Katrin Pröbstel untersuchen wir die Mechanismen der Neuroimmunologie mit einem besonderen Fokus auf Multiple Sklerose, MOG-Antikörperassoziierter Erkrankung und die Rolle des Mikrobioms im Krankheitsgeschehen. Wir erforschen, wie Immunzellen zur Entstehung und Aufrechterhaltung neuroinflammatorischer Prozesse beitragen und welche molekularen Zielstrukturen sich daraus für zukünftige Therapien ableiten lassen. Unser interdisziplinäres Team verbindet modernste Methoden in Immunologie,
Mikrobiom-Forschung, Molekularbiologie und Therapieentwicklung. Gemeinsam mit klinischen und wissenschaftlichen Partnern arbeiten wir daran, neue Erkenntnisse aus dem Labor schneller in medizinisch relevante Anwendungen zu überführen. Dies mit dem Ziel, langfristig die Lebensqualität von Patientinnen und Patienten mit neuroimmunologischen Erkrankungen zu verbessern. Wenn Sie Freude an präziser Laborarbeit, Neugier für innovative Forschung und Mitarbeit in einem engagierten Team mitbringen, freuen wir uns auf Ihre Bewerbung.
Nach Einarbeitung koordinieren und verantworten Sie die tierexperimentellen und keimfreien Mausstudien der Klinik für Neuroimmunologie angeschlossenen Forschungssektion:
- Zucht und Management von transgenen Mäusen
- Durchführung von Genotypisierungen (PCR, RT-PCR), Organisolierungen, Injektionen
und anderen Tierversuchen - Überwachung und Dokumentation von Tierversuchen gemäß den Genehmigungsanforderungen
- Durchführung von Zellkulturen, Durchflusszytometrie, Mikrobiologie und molekularbiologischen Experimenten (Klonierung, PCR, RT-PCR)
- Datenanalyse und -auswertung
- Mitwirkung bei der allgemeinen Labororganisation (z. B. Wartung der Geräte, Vorbereitung der Reagenzien)
- Schulung und Unterstützung von Kollegen bei der Durchführung von Tierversuchen
Wir wünschen uns:
- Abgeschlossene Berufsausbildung als Biologielaborant*in, BTA/MTA oder Studium (m/w/d)
- Mehrjährige, dokumentierte Erfahrung (z. B. für die Aufnahme in Tierversuchsanträge) in Tierversuchen inklusive Zucht und Management von transgenen Mäusen
- Erfahrung in der Arbeit mit keimfreien Mäusen ist ein zusätzlicher Vorteil
- Bereitschaft, neue Techniken und Analyseverfahren zu erlernen
- Hohes Maß an Motivation, Flexibilität und die Fähigkeit, in einem vielfältigen Team zu arbeiten
- Sorgfältige und unabhängige Arbeitsweise
- Gute organisatorische und interpersonelle Fähigkeiten
- Gute EDV-, Deutsch- und Englischkenntnisse
Wir bieten:
- Verantwortungsvoll und vielseitig: ein Arbeitsplatz mit großem Gestaltungsspielraum in einem kollegialen Team
- Bezahlung nach TV-L: Tarifliche Vergütung inkl. Jahressonderzahlung, betriebliche Altersvorsorge
- Flexibel für Familien: flexible Arbeitszeitmodelle, Möglichkeit auf einen Platz in der Betriebskindertagesstätte und Angebote für Elternzeitrückkehrer
- Clever zur Arbeit: Gute Anbindung an das SWB-Netz, Möglichkeit eines zinslosen Darlehens zur Anschaffung eines E-Bikes
- Geförderte Fortbildung: Individuelle Entwicklungschancen durch Kurse, E-Learning und Coachings
- Start mit System: Strukturiertes Onboarding
- Gesund am Arbeitsplatz: Zahlreiche Angebote der Gesundheitsförderung, kostenlose Mitgliedschaft im UKB-Fitnessstudio
- Arbeitgeberleistungen: Vergünstigte Angebote für Mitarbeiter*innen (Corporate Benefits)
Wir setzen uns für Diversität und Chancengleichheit ein. Unser Ziel ist es, den Anteil von Frauen in Bereichen, in denen Frauen unterrepräsentiert sind, zu erhöhen und deren Karrieren besonders zu fördern. Wir fordern deshalb einschlägig qualifizierte Frauen nachdrücklich zur Bewerbung auf. Bewerbungen werden in Übereinstimmung mit dem Landesgleichstellungsgesetz behandelt. Die Bewerbung geeigneter Menschen mit
nachgewiesener Schwerbehinderung und diesen gleichgestellten Personen ist besonders willkommen.
Kontakt
Sie erfüllen unsere Anforderungen und suchen eine abwechslungsreiche und herausfordernde Tätigkeit? Zögern Sie nicht und senden Sie Ihre aussagekräftige Bewerbung (bevorzugt per EMail in einer Datei bis 5 MB Größe) innerhalb von vier Wochen unter Angabe der Stellenanzeigen-Nr. ST-36006 an:
Prof. Dr. Anne-Katrin Pröbstel
Zentrum für Neurologie
Klinik für Neuroimmunologie
Venusberg-Campus 1
53127 Bonn
E-Mail: NIM.Forschung.Recruiting@ukbonn.de
www.ukbonn.de
Internships
You want to join one of our labs for an internship? We offer funding for
short-term scientific stays for up to four weeks in Bonn / Germany to
PostDocs and PhD students in their final year.
Please take a look at our scientific program for further information on our research areas. If you are a postdoc or PhD student in your final year and interested in a short term fellowship, please contact the principal investigator of the working group you are interested in directly. Your application should including your CV and a letter of motivation.
We are looking forward to hearing from you.