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PhD students in the lab

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Postdoctoral researcher (100%, TVL13) position in Spatial immunology of the Epididymis

The Rheinische Friedrich-Wilhelms-Universität Bonn is an international research university that offers a wide range of degree programs. With 200 years of history, about 38,000 students, over 6.000 employees, and an excellent domestic and international reputation, Bonn University is among Germany’s leading universities.

The Schlitzer Lab is looking for a highly motivated postdoc investigating mononuclear phagocytes' development and functional specialization during acute and chronic inflammation in the murine epididymis using state-of-the-art single-cell technologies. Starting at the earliest date possible for 3 years initially, this position will be integrated into the newly established DFG-funded research Unit INFINITE on epididymal Immunology, the Cluster of Excellence Immunosensation2, and the PRECISE platform of the University of Bonn, and the German Center for Neurodegenerative, diseases.


The Schlitzer Lab at the Life and Medical Sciences Institute (https://bit.ly/2RXDH0M) integrates spatial single-cell OMICS, high-dimensional imaging, and flow cytometry to unravel novel mechanisms and regulatory circuits during the functional specialization and development of mononuclear phagocytes.


1 Postdoctoral researcher (100%, TVL13) position in Spatial immunology of the Epididymis



Your profile:

• PhD degree in biomedical sciences, biology, bioinformatics, or a similar subject


• Strong background in immunology


• Strong background in Imaging or Spatial transcriptomics technologies


• Knowledge of flow cytometry


• Knowledge of the programming language R or Phyton


• excellent command of the English language


• motivated, flexible, team oriented and interested in continued professional development.


We offer:

• a varied and challenging position in a thriving academic environment


• access to state-of-the-art spatial single cell biology methods


• embedding with an established cluster of excellence in Immunology and a


newly established Research unit on epididymal Immunology


• a professional career development program


• participation in the university-wide pension system (VBL)


• access to the extensive university sports program


• a salary based on the TV-L scale


The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university and aims to increase the proportion of women employed in areas where women are underrepresented and to promote their careers. To that end, it urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable candidates with a certified disability or equivalent status are welcome.


If you are interested in this position, please send your complete application documents by 17.05.2024 to andreas.schlitzer@uni-bonn.de with the application code INFINITE/Bonn/Schlitzer. A full application should consist of a CV, a one-page summary of your previous work, and the contact details of two referees. Before sending your application, please combine and convert all of your documents into one PDF file.

For further information, please contact Andreas Schlitzer (Tel.: 0228/7362847).

Doctoral student (65%, TVL13) position in Spatial immunology of the Epididymis

The Rheinische Friedrich-Wilhelms-Universität Bonn is an international research university that offers a wide range of degree programs. With 200 years of history, about 38,000 students, over 6.000 employees, and an excellent domestic and international reputation, Bonn University is among Germany’s leadinguniversities.

The Schlitzer Lab is looking for a highly motivated doctoral student investigating mononuclear phagocytes' development and functional specialization during acute and chronic inflammation in the murine epididymis using state-of-the-art single-cell technologies. Starting at the earliest date possible for 3 years initially, this position will be integrated into the newly established DFG-funded research Unit INFINITE on epididymal Immunology, the Cluster of Excellence Immunosensation2, and the PRECISE platform of the University of Bonn, and the German Center for Neurodegenerative, diseases.


The Schlitzer Lab at the Life and Medical Sciences Institute (https://bit.ly/2RXDH0M) integrates spatial single-cell OMICS, high-dimensional imaging, and flow cytometry to unravel novel mechanisms and regulatory circuits during the functional specialization and development of mononuclear phagocytes.


1 Doctoral student (65%, TVL13) position in Spatial immunology of the Epididymis



Your profile:

• Master degree in biomedical sciences, biology, bioinformatics, or a similar subject


• Background in Immunology


• Background in Imaging or Spatial transcriptomics technologies


• Willingness to work with animals


• Knowledge of flow cytometry


• Knowledge of the programming language R or Phyton


• excellent command of the English language


• motivated, flexible, team oriented and interested in continued professional development.


We offer:

• a varied and challenging position in a thriving academic environment


• access to state-of-the-art spatial single cell biology methods


• embedding with an established cluster of excellence in Immunology and a newly established Research unit on epididymal Immunology


• Integration into the graduate school of the Cluster of Excellence Immunosensation2


• a professional career development program


• participation in the university-wide pension system (VBL)


• access to the extensive university sports program


• a salary based on the TV-L scale


The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university and aims to increase the proportion of women employed in areas where women are underrepresented and to promote their careers. To that end, it urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable candidates with a certified disability or equivalent status are welcome.


If you are interested in this position, please send your complete application documents by 17.05.2024 to andreas.schlitzer@uni-bonn.de with the application code INFINITE/Bonn/Schlitzer. A full application should consist of a CV, a one-page summary of your previous work, and the contact details of two referees. Before sending your application, please combine and convert all of your documents into one PDF file. For further information, please contact Andreas Schlitzer (Tel.: 0228/7362847).

PhD position – Mucosal Immunology and microbiota research (m/f/o)

Available immediately for three years with the possibility of extension.


A PhD position is available to study the intestinal antibody response to the microbiota. Therefore, we will employ single B cell immunoglobulin gene sequencing, sequence-guided gene synthesis, monoclonal antibody production, antibody binding assays, germ-free, and gnotobiotic mouse models, in vivo bacterial transcriptomics, and single cell host transcriptomic analysis. Our aim is to obtain a detailed mechanistic understanding of the effects of Immunoglobulin A on the bacterial target cell and the host immune system.


For related previous work see the following links:

https://www.nature.com/articles/s41586-021-03973-7

https://www.nature.com/articles/s41590-018-0106-2


We offer:

The University of Bonn is a German University of Excellence since 2019. The medical faculty is a hub for internationally recognised immunological institutes and part of the Immunosensation2 cluster of excellence in Germany (www.immunosensation.com). The Department of Mucosal Immunology is newly founded within the Institute of Molecular Medicine and Experimental Immunology (www.immei.de).

- Excellent working conditions and competitive remuneration.

- Dynamic, multidisciplinary, and international setting with strong immunology focus.

- To become part of the Graduate school with additional workshops, lectures, networking events and conferences (www.bigs-immuno.uni-bonn.de)

- Participation in national and international conferences.

- The possibility to apply for the internal slots of International School on Advanced Immunology.

- Living in an active university city with access to many cultural possibilities.

- Salary according to the German TV-L13 65% and additional benefits such as a pension plan.

- Although the position is fully funded, we fully support your applications for career advancement grants or PhD research fellowships.

- Possibility to co-supervise undergraduate students or technicians

- Close supervision in regular meetings

- State of the art equipment and scientific methods to answer your research questions

- Core facilities to support your research


Your profile:

- Excellent study or research performance.

- You possess high scientific integrity.

- Master’s degree (or equivalent) in immunology, biology, biomedicine, microbiology or similar.

- The project requires animal experimentation (mice), and previous exposure to in vivo work would be advantageous.

- Basic knowledge in immunology, life sciences and molecular biology.

- Ability to work precisely in the laboratory environment.

- Interest to learn germ-free and gnotobiotic animal handling techniques.

- Experience and/or interest to perform data analysis of BCR repertoire and bacterial genomic data using programming languages (mostly R).

- Successful candidates can think independently, are eager to acquire necessary new skills, and are excellent collaborators and communicators.


To apply:

Application documents include a motivation letter, detailed CV (including the names of former mentors and supervisors), publication list (if applicable), relevant transcripts, and recommendation letters and/or contact information of at least two references.

To apply, please send all the required documents in a single .pdf document by e-mail (Subject: PhD application [Name]) to tim.rollenske@uni-bonn.de

Application deadline is the 10th April 2024. Starting date is negotiable.

We are strongly committed to promote equal opportunities independent of gender, ethnicity, age, nationality, religion, disability, etc.. Therefore, applications will be handled in accordance with the State Equality Act.

Additional information:

Institute homepage: www.immei.de

Contact:

Prof. Dr. Tim Rollenske: tim.rollenske@uni-bonn.de

PhD student position at the Department of Anaesthesiology and Intensive Care Medicine

The group of PD Dr. med. Christina Weisheit at the Department of Anaesthesiology and Intensive care Medicine at the University Hospital Bonn is looking for a


PhD student (German salary scale TVL 13 65%).



The DFG approved project „The role of the senescent innate and adaptive immune system in the development of Aortic valve stenosis” is a collaborative project of three working groups in Cologne and Bonn. To analyse the influence of ageing in the immune response in aortic valve stenosis (AS), the department of Anaesthesiology and Intensive Care Medicine of the University Hospital Bonn offers a PhD student position over a period of 3 years. The project will address the role of age on myeloid and lymphoid leukocyte subsets and their role in the pathogenesis of aortic valve stenosis, a progressive inflammatory disease that is, impeding blood ejection from the left ventricle and causing serious cardiovascular complications.

We are seeking a highly motivated and talented candidate with a strong interest in immunology and cardiovascular diseases with the following profile:

- Diploma thesis or Master’s degree in biology, biochemistry, pharmacy, biomedicine or similar.

- Basic knowledge in immunology, life sciences and cellular techniques.

- Excellent skills for team working and communication (oral and writing) in English.

- Experience with in vivo and in vitro experimental models, flow cytometry, and gene sequencing are advantageous.

Doctoral students will participate in a structured program that promotes scientific education and longterm development of medical scientists to pursue their career in the field of translational cardiovascular science.

The University of Bonn is committed to being an equal opportunity employer in our recruitment efforts. Preference will be given to suitably qualified female applicants or handicapped people, all other considerations being equal.

Application:

Please send a Letter of Motivation, C.V. and certificates to PD Dr. med. Christina Weisheit via email to Christina.Weisheit@ukbonn.de using reference number 24-B

Post-Doc position at the Institute of Innate Immunity

Position: Post-Doc position available at the Institute of Innate Immunity

Project: Immune and Molecular Mechanisms Driving Post-Sepsis Immunosuppression


Starting Date: From February 2024

Location: Franklin Lab/Institute of Innate Immunity, Bonn



Are you passionate about unraveling the mysteries of the immune system and its responses to critical conditions? Do you want to make a significant impact on the field of immunology while working alongside a dynamic and dedicated team of researchers? Look no further – an exciting Post-Doc position is available in the Franklin Lab at the Institute of Innate Immunity (III) of the University of Bonn.

About Us: The III is a leading research facility dedicated to advancing our understanding of immunology and its implications for human health. Our team comprises experts from diverse backgrounds, including cell biology, immunology, and proteomics. The III is committed to fostering an environment of collaboration and innovation, and provide an ideal platform for researchers to grow and thrive.

Project Overview: Sepsis, a life-threatening response to infection, can lead to a complex and poorly understood condition called post-sepsis immunosuppression. As a Post-Doctoral Fellow in our lab, you will investigate the intricate immune and molecular mechanisms underlying post-sepsis immunosuppression. This EU-funded research will contribute to identifying potential therapeutic targets that can alleviate the immune dysfunction seen in patients recovering from sepsis.


Qualifications:

- A Ph.D. in Immunology, Cellular and Molecular Biology, or a related field.

- Strong background in immunological techniques, cellular and molecular assays.

- Proven track record of scientific productivity demonstrated by publications.

- Ability to work effectively in a team.


What We Offer:

- State-of-the-art laboratory facilities and resources.

- Mentorship from accomplished researchers in the field.

- Opportunities for career development and networking.

- Vibrant and collaborative research environment.


Application Process: To apply, please submit the following documents to franklin@uni-bonn.de:

CV including a list of publications.
Contact information for at least two professional references.

Join our team and be part of the journey towards understanding and combatting post-sepsis immunosuppression. For more information, please visit www.iii-bonn.de and learn more about our work and the exciting research environment you could be a part of.

Internships

You want to join one of our labs for an internship? We offer funding for
short-term scientific stays for up to four weeks in Bonn / Germany to
PostDocs and PhD students in their final year.

Please take a look at our scientific program for further information on our research areas. If you are a postdoc or PhD student in your final year and interested in a short term fellowship, please contact
immunosensation@uni-bonn.de
, including your CV, a letter of motivation and a statement which research group you would like to join.

We are looking forward to hearing from you.

Join us for an internship