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Prof. Dr. Kaan Boztug

Clinic for Pediatric Immunology and Rheumatology

Venusberg-Campus 1, 53127 Bonn

kaan.boztug@ukbonn.de

The research of Kaan Boztug focuses on uncovering the genetic and molecular foundations of rare immune system disorders. His work has led to the discovery of more than 20 previously unknown inborn errors of immunity. These findings have been pivotal in elucidating the roles of specific genes and proteins in immune system dysfunction, with a focus on immunodeficiencies characterised by susceptibility to infections, as well as immune dysregulation that influence autoimmunity and autoinflammation.

Prof. Dr. Kaan Boztug

Recent publications

  • Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes.

    Science immunology

    Authors: Artem Kalinichenko, Jakob Huemer, Theresa Humer, Matthias Haimel, Michael Svaton, Nicolas Socquet-Juglard, Giovanna Perinetti Casoni, Celine Prakash, Maximilian von der Linde, Julia Pazmandi, Cheryl van de Wetering, Javier Nunez-Fontarnau, Anton Kamnev, Sarah Giuliani, Martin G Jaeger, Elisa Hahn, Sarah Dobner, Andrea Rukavina, Elise Sylvander, Jacqueline Seigner, Christina Rashkova, Birgit Hoeger, Michael W Traxlmayr, Manfred Lehner, Yenan T Bryceson, Janna Saarela, Thomas Hannich, Irinka Castanon, Georg Winter, Loïc Dupré, Kaan Boztug

  • Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation.

    Nature reviews. Immunology

    Authors: Loïc Dupré, Irinka Castanon, Kaan Boztug

  • Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML.

    Cell reports. Medicine

    Authors: Ben Haladik, Margarita Maurer-Granofszky, Peter Zoescher, Raul Jimenez-Heredia, Alexandra Frohne, Anna Segarra-Roca, Chloe Casey, Felix Kartnig, Sarah Giuliani, Christina Rashkova, Peter Repiscak, Michael N Dworzak, Giulio Superti-Furga, Kaan Boztug

All publications by Prof. Dr. Kaan Boztug