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Dr. Róisín McManus

Member

Institute of Innate Immunity

DZNE, Venusberg-Campus 1, 53127 Bonn

Roisin.McManus@dzne.de

+49 228 43302342

Our research focus is on Neuroimmunology. Our group make use of preclinical models and clinical samples to uncover how environmental factors like diet contribute to the progression of dementia. We are particularly interested in the role of chronic innate immune activation and metabolic signaling pathways in this process. A major goal of the McManus lab is to use these insights to identify novel immune-targeted therapies that could provide better, patient-specific options for individuals with Alzheimer’s disease and dementia.

Dr. Roisin McManus

Recent publications

  • Naphtho[1,2-][1,4]diazepinedione-Based P2X4 Receptor Antagonists from Structure-Activity Relationship Studies toward PET Tracer Development.

    Journal of medicinal chemistry

    Authors: Katharina Sophie Erlitz, Ann-Kathrin Prinz, Stefan Wagner, Joana Massa, Calvin Dunker, Meike Höhl, Angelika Griep, Róisín M McManus, Sonja Schelhaas, Oliver Koch, Anna Junker

  • Basic Science and Pathogenesis.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Roisin M McManus

All publications by Dr. Róisín McManus