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TGF-β specifies T versus T17 cell fates in murine CD4 T cells through c-Maf.
Science immunology
View this publicationMember, Steering-Committee Member
Medical Faculty, University of Bonn University Hospital of Bonn Venusberg-Campus 1 53127 Bonn
We have a long-standing interest in elucidating the molecular and cellular mechanisms that regulate T helper cell fate decisions and functions in various physiological and disease settings, including infection, vaccination, autoimmunity, and cancer. Using sophisticated in vivo models and patient-derived samples, we are particularly interested in understanding T follicular helper (Tfh) cells, which provide essential help for potent antibody responses, e.g. through their interactions with B cells in germinal centers
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Science immunology
View this publicationProceedings of the National Academy of Sciences of the United States of America
View this publicationNature immunology
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