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Prof. Dr. Andreas Schlitzer

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

aschlitz@uni-bonn.de

+49 228 7362738

Website

The aim of our research is to understand the complexity and function of dendritic cells and monocytes during health and disease. A major focus lies on the developmental processes leading to the functional specialization of dendritic cell subsets and monocytes. To analyse these highly heterogeneous compartments we use state of the art technologies such as single cell mRNA sequencing, multi-colour fish and advanced flow cytometry. Taken together we are investigating how the development of dendritic cells and monocytes shapes their functional specialization during homeostasis and disease.

Recent publications

  • Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF.

    Nature immunology

    Authors: Frederike Westermann, Selma Tuzlak, Victor Kreiner, Aline Ignacio, David Bejarano, Mitchell Bijnen, Virginia Cecconi, Hannah van Hove, Haiting Wang, Myrto Andreadou, Gioana Litscher, Colin Sparano, Ricardo Fróis-Martins, Alexandre Gallerand, Elsa Roussel, Laura Oberbichler, Rachel Lindemann, Donatella DeFeo, Zhaoyuan Liu, Anja Kipar, Salomé LeibundGut-Landmann, Kathy McCoy, Iain Nixon, Calum C Bain, Christoph Schneider, Stoyan Ivanov, Sonia Tugues, Melanie Greter, Florent Ginhoux, Andreas Schlitzer, Elaine Emmerson, Burkhard Becher

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  • An islet-resident macrophage antioxidant program preserves β cell physiology.

    Science immunology

    Authors: Amélie Grosjean, Aude Jalon, Claire Leveau, Marc Diedisheim, David Alejandro Bejarano, Joyceline Cuenco, Kevin Mulder, Zhaoyuan Liu, Audrey Le Guernic, Marie-Laure Island, Jarne Walkiers, Gamze Ates, Clément Materne, Andreia Goncalves, Ivan Nemazanyy, Laura G Baudrin, Sylvain Baulande, Martine Ropert, Jean-François Gautier, Ahmed Hamaï, Andreas Schlitzer, Florent Ginhoux, Ann Massie, Nicolas Venteclef, Elise Dalmas

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  • A dynamic model for Waddington's landscape accounting for cell-to-cell communication.

    Mathematical biosciences

    Authors: Simon Merkt, Lara Fuhrmann, Erika Dudkin, Andreas Schlitzer, Barbara Niethammer, Jan Hasenauer

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