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Prof. Dr. Andreas Schlitzer

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

aschlitz@uni-bonn.de

+49 228 7362738

Website

The aim of our research is to understand the complexity and function of dendritic cells and monocytes during health and disease. A major focus lies on the developmental processes leading to the functional specialization of dendritic cell subsets and monocytes. To analyse these highly heterogeneous compartments we use state of the art technologies such as single cell mRNA sequencing, multi-colour fish and advanced flow cytometry. Taken together we are investigating how the development of dendritic cells and monocytes shapes their functional specialization during homeostasis and disease.

Recent publications

  • Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming.

    Nature

    Authors: Jean-Rémi Lavillegrand, Rida Al-Rifai, Sara Thietart, Théo Guyon, Marie Vandestienne, Raphael Cohen, Vincent Duval, Xiaodan Zhong, Daniel Yen, Mumin Ozturk, Yutaka Negishi, Joanne Konkel, Emmanuel Pinteaux, Olivia Lenoir, Jose Vilar, Ludivine Laurans, Bruno Esposito, Marius Bredon, Harry Sokol, Marc Diedisheim, Antoine-Emmanuel Saliba, Alma Zernecke, Clément Cochain, Jessica Haub, Alain Tedgui, Nancy A Speck, Soraya Taleb, Musa M Mhlanga, Andreas Schlitzer, Niels P Riksen, Hafid Ait-Oufella

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  • Amplification of autoimmune organ damage by NKp46-activated ILC1.

    Nature

    Authors: Stylianos-Iason Biniaris-Georgallis, Tom Aschman, Katerina Stergioula, Frauke Schreiber, Vajiheh Jafari, Anna Taranko, Tejal Karmalkar, Ana Kasapi, Tihana Lenac Rovis, Vedrana Jelencic, David A Bejarano, Lea Fabry, Michail Papacharalampous, Irene Mattiola, Martina Molgora, Jinchao Hou, Karolin W Hublitz, Frederik Heinrich, Gabriela Maria Guerra, Pawel Durek, Giannino Patone, Eric Lars-Helge Lindberg, Henrike Maatz, Oliver Hölsken, Gerhard Krönke, Arthur Mortha, Reinhard E Voll, Alexander J Clarke, Anja E Hauser, Marco Colonna, Kevin Thurley, Andreas Schlitzer, Christoph Schneider, Efstathios G Stamatiades, Mir-Farzin Mashreghi, Stipan Jonjic, Norbert Hübner, Andreas Diefenbach, Masatoshi Kanda, Antigoni Triantafyllopoulou

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  • Timing and location dictate monocyte fate and their transition to tumor-associated macrophages.

    Science immunology

    Authors: Garett Dunsmore, Wei Guo, Ziyi Li, David Alejandro Bejarano, Rhea Pai, Katharine Yang, Immanuel Kwok, Leonard Tan, Melissa Ng, Carlos De La Calle Fabregat, Aline Yatim, Antoine Bougouin, Kevin Mulder, Jake Thomas, Javiera Villar, Mathilde Bied, Benoit Kloeckner, Charles-Antoine Dutertre, Grégoire Gessain, Svetoslav Chakarov, Zhaoyuan Liu, Jean-Yves Scoazec, Ana-Maria Lennon-Dumenil, Thomas Marichal, Catherine Sautès-Fridman, Wolf Herman Fridman, Ankur Sharma, Bing Su, Andreas Schlitzer, Lai Guan Ng, Camille Blériot, Florent Ginhoux

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