Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity.
Frontiers in immunology
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Carl-Troll-Strasse 31, 53115 Bonn
My main research interest lies in understanding the epigenetic and metabolic processes governing immune cell responses. We study these mechanisms using mouse models and patient material in the context of chromatinopaties caused by epigenetic enzyme deficiencies and gd T cell-based therapies. The aim of our research is to inform future therapeutic interventions.
Frontiers in immunology
View this publicationThe Journal of clinical investigation
View this publicationThe Journal of clinical endocrinology and metabolism
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