Skip to main content

Jun.-Prof. Dr. Elena Reckzeh

Member

Life and Medical Sciences Institute (Limes)

Carl-Troll-Straße 31, 53115 Bonn

ereckzeh@uni-bonn.de

+49 228 7362777

The AG Reckzeh uses stem cell-derived model systems of the gut (organoids, mini-organs) and colon tumors (tumor-organoids) to study extrinsic and intrinsic influences on nutrient uptake, dependence and flexibility. We are especially interested in key regulators mediating metabolic adaptation. We use our organoid models to find new biologically active substances (compounds) to study metabolic phenomena.

Jun.-Prof. Dr. Elena Reckzeh

Recent publications

  • Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling.

    Journal of medicinal chemistry

    Authors: Ruirui Zhang, Maxim A Huetzen, Aylin Binici, Pablo Martín-Gago, Raphael Gasper, Elena Rudashevskaya, Jie Liu, Chinta Nagaraju, Elena S Reckzeh, Alana S T Stuedle, Ann-Sophie Hopff, Andrea Mesaros, Anke Unger, Melanie Thelen, Petra Janning, H Christian Reinhardt, Slava Ziegler, Ron D Jachimowicz, Herbert Waldmann

  • Opportunities of patient-derived organoids in drug development.

    British journal of pharmacology

    Authors: Antonia Büning, Elena Reckzeh

All publications by Jun.-Prof. Dr. Elena Reckzeh