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Jun.-Prof. Dr. Marie-Christine Simon

Member

Institute of Nutrition and Food Sciences

Nutritional Physiology, Faculty of Agriculture, University of Bonn Nussallee 9

marie-christine.simon@uni-bonn.de

+49 228 733814

Website

We are interested to investigate the link between diet, gut microbiota and cognition, since consumption of a Western diet rich in fat (>34%) and sugars with high glycemic load (19% of total energy) may lead to obesity, type 2 diabetes mellitus and cardiovascular disease. Furthermore, the “microbiota-gut-brain axis” has recently been proposed as a mechanistic link in the development of cognitive functions. According to this hypothesis, dietary behavior may be a critical factor in the development and maintenance of cognitive function. In this regard, our goal is to translate current findings from animal and observational studies into human intervention studies with a translational approach to elucidate this complex interaction of diet, microbiota and brain.

Marie-Christine Simon

Recent publications

  • Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality.

    iScience

    Authors: Laura Schlautmann, Daniel Burgdorf, Shaunak Ghosh, Alina Schieren, Linda Klümpen, Isabel Stötzel, Julia Bremser, Michael Döngi, Elvira Mass, Valentin Stein, Thomas Quast, Waldemar Kolanus, Thorsten Lang, Eva Kiermaier, Marie-Christine Simon, Sven Burgdorf

  • A prebiotic dietary pilot intervention restores faecal metabolites and may be neuroprotective in Parkinson's Disease.

    NPJ Parkinson's disease

    Authors: Janis Rebecca Bedarf, Stefano Romano, Silke Sophie Heinzmann, Anthony Duncan, Maria H Traka, Duncan Ng, Daniella Segovia-Lizano, Marie-Christine Simon, Arjan Narbad, Ullrich Wüllner, Falk Hildebrand

  • The Multiple Challenges of Nutritional Microbiome Research During COVID-19-A Perspective and Results of a Single-Case Study.

    Nutrients

    Authors: Anna Donkers, Waldemar Seel, Linda Klümpen, Marie-Christine Simon

All publications by Jun.-Prof. Dr. Marie-Christine Simon