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Jun.-Prof. Dr. Marie-Christine Simon

Member

Institute of Nutrition and Food Sciences

Nutritional Physiology, Faculty of Agriculture, University of Bonn Nussallee 9

marie-christine.simon@uni-bonn.de

+49 228 733814

Website

We are interested to investigate the link between diet, gut microbiota and cognition, since consumption of a Western diet rich in fat (>34%) and sugars with high glycemic load (19% of total energy) may lead to obesity, type 2 diabetes mellitus and cardiovascular disease. Furthermore, the “microbiota-gut-brain axis” has recently been proposed as a mechanistic link in the development of cognitive functions. According to this hypothesis, dietary behavior may be a critical factor in the development and maintenance of cognitive function. In this regard, our goal is to translate current findings from animal and observational studies into human intervention studies with a translational approach to elucidate this complex interaction of diet, microbiota and brain.

Marie-Christine Simon

Recent publications

  • The MicroIBioM study: the gut microbiome in inclusion body myositis.

    Clinical and experimental rheumatology

    Authors: Maren Winkler, Waldemar Seel, Cornelia Kornblum, Marie-Christine Simon, Jens Reimann

  • Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

    Nature communications

    Authors: Linda Klümpen, Aakash Mantri, Maren Philipps, Waldemar Seel, Laura Schlautmann, Mohamed H Yaghmour, Verena Wiemann, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Jan Hasenauer, Thomas Fließwasser, Sven Burgdorf, Christoph Thiele, Peter Stehle, Marie-Christine Simon

  • Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality.

    iScience

    Authors: Laura Schlautmann, Daniel Burgdorf, Shaunak Ghosh, Alina Schieren, Linda Klümpen, Isabel Stötzel, Julia Bremser, Michael Döngi, Elvira Mass, Valentin Stein, Thomas Quast, Waldemar Kolanus, Thorsten Lang, Eva Kiermaier, Marie-Christine Simon, Sven Burgdorf

All publications by Jun.-Prof. Dr. Marie-Christine Simon