Skip to main content

Jun.-Prof. Dr. Marie-Christine Simon


Institute of Nutrition and Food Sciences

Nutritional Physiology, Faculty of Agriculture, University of Bonn Nussallee 9

+49 228 733814


We are interested to investigate the link between diet, gut microbiota and cognition, since consumption of a Western diet rich in fat (>34%) and sugars with high glycemic load (19% of total energy) may lead to obesity, type 2 diabetes mellitus and cardiovascular disease. Furthermore, the “microbiota-gut-brain axis” has recently been proposed as a mechanistic link in the development of cognitive functions. According to this hypothesis, dietary behavior may be a critical factor in the development and maintenance of cognitive function. In this regard, our goal is to translate current findings from animal and observational studies into human intervention studies with a translational approach to elucidate this complex interaction of diet, microbiota and brain.

Marie-Christine Simon

Recent publications

  • Fat from Hermetia illucens alters the cecal gut microbiome and lowers hepatic triglyceride concentration in comparison to palm oil in obese Zucker rats.

    The Journal of nutrition

    Authors: Magdalena J M Marschall, Sarah M Grundmann, Waldemar Seel, Marie-Christine Simon, Sven Schuchardt, Erika Most, Denise K Gessner, Gaiping Wen, Robert Ringseis, Klaus Eder

    View this publication
  • Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy adults.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Hanna Huber, Nicholas J Ashton, Alina Schieren, Laia Montoliu-Gaya, Guglielmo Di Molfetta, Wagner S Brum, Juan Lantero-Rodriguez, Lana Grötschel, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Matthias Schmid, Kaj Blennow, Peter Stehle, Henrik Zetterberg, Marie-Christine Simon

    View this publication
  • Role of Dietary Fiber and Energy Intake on Gut Microbiome in Vegans, Vegetarians, and Flexitarians in Comparison to Omnivores-Insights from the Nutritional Evaluation (NuEva) Study.


    Authors: Waldemar Seel, Sarah Reiners, Kristin Kipp, Marie-Christin Simon, Christine Dawczynski

    View this publication