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PD Dr. Christina Weisheit

Member, Alumnus / Alumna

Department of Anesthesiology and Intensive Care Medicine

Christina.weisheit@ukbonn.de

Website

PD Dr. Christina Weisheit is highly interested in the intersection of the immune system and cardiovascular diseases with a particular emphasis on understanding the immunological mechanisms underlying aortic disease development. She investigates how various factors such as the gut microbiome, changes in the metabolom signature, aging and bacterial infection influence aortic valve diseases using a combination of clinical data sets, patient samples, and experimental models. Dr. Weisheit's work aims at understanding cardiovascular disease progression and development modulated by the immune system and the gut microbiome, providing insights that may contribute to the development of interventions for aortic valve disorders and biomarker selection.

Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinik Bonn

Recent publications

  • Gut microbiome composition differs between aortic stenosis and aortic regurgitation patients.

    Scientific reports

    Authors: Benedikt Bartsch, Svetozar Nesic, Muntadher Al Zaidi, Raul Nicolas Jamin, Ansgar Ackerschott, Nikola Lübbering, Hannah Billig, Axel Schott, Chiara Hesse, Marijo Parcina, Marwan Hamiko, Farhad Bakhtiary, Georg Nickenig, Christian Kurts, Sebastian Zimmer, Christina Katharina Weisheit

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  • Predicting Macrophage Spatial Localization from Single-Cell Transcriptomes to Uncover Disease Mechanisms.

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    Authors: Junping Yin, Qi Mei, Hans-Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K Weisheit, Veronika Lukacs-Kornek, Isis Ludwig-Portugall, Sibylle von Vietinghoff, Christian F Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li

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  • Low-dose glucocorticoids attenuate crescentic glomerulonephritis by inhibiting the local differentiation of proinflammatory neutrophils.

    Science translational medicine

    Authors: Junping Yin, Melanie Eichler, Darius P Schaub, Nariaki Asada, Jonas Engesser, Clivia Lisowski, Hans-Joachim Paust, Christina Katharina Weisheit, Jian Li, Daniela Klaus, Natalio Garbi, Sibylle von Vietinghoff, Christian F Krebs, Ulf Panzer, Christian Kurts

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