Predicting Macrophage Spatial Localization from Single-Cell Transcriptomes to Uncover Disease Mechanisms.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
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PD Dr. Christina Weisheit is highly interested in the intersection of the immune system and cardiovascular diseases with a particular emphasis on understanding the immunological mechanisms underlying aortic disease development. She investigates how various factors such as the gut microbiome, changes in the metabolom signature, aging and bacterial infection influence aortic valve diseases using a combination of clinical data sets, patient samples, and experimental models. Dr. Weisheit's work aims at understanding cardiovascular disease progression and development modulated by the immune system and the gut microbiome, providing insights that may contribute to the development of interventions for aortic valve disorders and biomarker selection.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
View this publicationScience translational medicine
View this publicationPloS one
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