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Prof. Dr. Alfredo Ramirez

Member

Department of Psychiatry and Psychotherapy, University of Cologne

Kerpener Str. 62, 50931 Cologne

alfredo.ramirez@uk-koeln.de

The main objective of Dr. Ramirez’s laboratory is the identification of the genetic and epigenetic architecture that influences the disease processes underlying cognitive disorders such as Alzheimer’s disease. A key focus of his research is identifying the molecular mechanisms at the intersection of ageing and Alzheimer’s disease that drive cognitive decline. His group combines (epi)genomics and proteomics to study cellular senescence, a key mechanism that triggers chronic inflammation through the senescence-associated secretory phenotype (SASP).

Prof. Dr. Alfredo Ramirez

Recent publications

  • Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.

    Nature communications

    Authors: Inga Menze, Jose Bernal, Rogier A Kievit, Kumar Parijat Tripathi, Timo Kaleck, Renat Yakupov, Slawek Altenstein, Claudia Bartels, Katharina Buerger, Michaela Butryn, Peter Dechent, Michael Ewers, Klaus Fliessbach, Ingo Frommann, Maria Gemenetzi, Wenzel Glanz, Daria Gref, Julian Hellmann-Regen, Stefan Hetzer, Enise I Incesoy, Daniel Janowitz, Ingo Kiliman, Luca Kleineidam, Marie Theres Kronmüller, Christoph Laske, Debora Melo van Lent, Falk Lüsebrink, Robert Perneczky, Oliver Peters, Lukas Preis, Josef Priller, Boris-Stephan Rauchmann, Ayda Rostamzadeh, Sandra Roeske, Klaus Scheffler, Björn-Hendrik Schott, Anja Schneider, Sebastian Sodenkamp, Annika Spottke, Eike Jakob Spruth, Melina Stark, Stefan Teipel, Michael Wagner, Jens Wiltfang, Frank Jessen, Alfredo Ramirez, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler

  • Diagnostic Images for Mild Cognitive Impairment Are Sensitive to Alzheimer's Disease Biomarkers and Reveal Abnormal Scene Processing.

    Journal of cognitive neuroscience

    Authors: Yuetong Bai, Oliver Peters, Silka Dawn Freiesleben, Friederike Fenski, Josef Priller, Eike Jakob Spruth, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Claudia Bartels, Ayda Rostamzadeh, Wenzel Glanz, Stefan Teipel, Ingo Kilimann, Christoph Laske, Matthias H Munk, Annika Spottke, Nina Roy-Kluth, Frederic Brosseron, Michael Wagner, Ingo Frommann, Falk Lüsebrink, Alfredo Ramirez, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Renat Yakupov, Frank Jessen, Emrah Düzel, Wilma A Bainbridge

  • Subjective cognition trajectories, Alzheimer biomarkers, and incident mild cognitive impairment.

    The journal of prevention of Alzheimer's disease

    Authors: Elizabeth Kuhn, Luca Kleineidam, Melina Stark, Oliver Peters, Julian Hellmann-Regen, Lukas Preis, Daria Gref, Josef Priller, Eike Jakob Spruth, Maria Gemenetzi, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Claudia Bartels, Niels Hansen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise Incesoy, Katharina Buerger, Daniel Janowitz, Sophia Stöcklein, Robert Perneczky, Boris-Stephan Rauchmann, Stefan J Teipel, Ingo Kilimann, Christoph Laske, Sebastian Sodenkamp, Annika Spottke, Marie Kronmüller, Sandra Roeske, Frederic Brosseron, Alfredo Ramirez, Matthis Synofzik, Matthias C Schmid, Frank Jessen, Michael Wagner

All publications by Prof. Dr. Alfredo Ramirez