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Prof. Dr. Alfredo Ramirez

Member

Department of Psychiatry and Psychotherapy, University of Cologne

Kerpener Str. 62, 50931 Cologne

alfredo.ramirez@uk-koeln.de

The main objective of Dr. Ramirez’s laboratory is the identification of the genetic and epigenetic architecture that influences the disease processes underlying cognitive disorders such as Alzheimer’s disease. A key focus of his research is identifying the molecular mechanisms at the intersection of ageing and Alzheimer’s disease that drive cognitive decline. His group combines (epi)genomics and proteomics to study cellular senescence, a key mechanism that triggers chronic inflammation through the senescence-associated secretory phenotype (SASP).

Prof. Dr. Alfredo Ramirez

Recent publications

  • Plasma GFAP outperforms CSF GFAP in detecting amyloid pathology and is associated with increased risk of clinical progression in early Alzheimer's disease.

    The journal of prevention of Alzheimer's disease

    Authors: Arda C Cetindag, Carola G Schipke, Hermann Esselmann, Niels Kruse, Jens Wiltfang, Anja Schneider, Klaus Fliessbach, Carolin Miklitz, Franziska Maier, Katharina Buerger, Daniel Janowitz, Michael Ewers, Sophia Stöcklein, Robert Perneczky, Boris-Stephan Rauchmann, Carolin Kurz, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Sebastian Sodenkamp, Elham Najafpour, Michael Wagner, Sandra Roeske, Ingo Frommann, Melina Stark, Frederic Brosseron, Alfredo Ramirez, Luca Kleineidam, Josef Priller, Eike Jakob Spruth, Maria Gemenetzi, Slawek Altenstein, Emrah Düzel, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Chris Bauer, Frank Jessen, Oliver Peters

  • Microglia protein profiles in CSF across Alzheimer's disease clinical stages.

    Nature aging

    Authors: Elena-Raluca Blujdea, Pieter van Bokhoven, Pamela V Martino-Adami, Victoria S Marshe, Ellen M Vromen, Yanaika S Hok-A-Hin, Walter A Boiten, David J Irwin, Alice S Chen-Plotkin, Afina W Lemstra, Yolande Pijnenburg, Wiesje M van der Flier, Oliver Peters, Julian Hellmann-Regen, Josef Priller, Anja Schneider, Jens Wiltfang, Frank Jessen, Emrah Düzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Frederic Brosseron, Marta Del Campo, Ruud Wijdeven, Pieter-Jelle Visser, Betty M Tijms, Philip L De Jager, Alfredo Ramirez, Charlotte E Teunissen, Lisa Vermunt

  • Predicting longitudinal basal forebrain volume in the Alzheimer's disease spectrum: the role of sex and ApoE epsilon 4 genotype.

    Frontiers in neuroscience

    Authors: Alice Grazia, Fedor Levin, Frank Jessen, Michael Wagner, Oliver Peters, Josef Priller, Anja Schneider, Jens Wiltfang, Emrah Düzel, Katharina Buerger, Robert Perneczky, Christoph Laske, Annika Spottke, Alfredo Ramirez, Stefan J Teipel

All publications by Prof. Dr. Alfredo Ramirez