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Prof. Dr. Anja Schneider

Member

Department of Cognitive Disorders and Old Age Psychiatry

anja.schneider@ukbonn.de

Website

My group has focused on fluid biomarkers for the detection of different neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, Frontotemporal Dementia and Amyotrophic Lateral Sclerosis, especially in early, preclinical disease stages. In particular, we are interested in extracellular vesicles, not only as biomarkers but also as modulators of inflammation, their role in cell-cell communication and as potential carriers of disease pathology in neurodegeneration. We are employing data and biomaterial from patient cohorts as well as cell culture and murine models to elucidate the contribution of microglia to disease pathology in Alzheimer’s and Parkinson’s disease.

Recent publications

  • Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Timo Kaleck, Rafael Campos-Martin, Amanda Cano, Maria Victoria Fernández, Pamela Martino-Adami, Luca Kleineidam, Victor M Andrade Fuentes, Kumar P Tripathi, Kayenat Parveen, Raquel Puerta, Itziar de Rojas, Kishore A Ravichandran, Oliver Peters, Julian Hellmann-Regen, Josef Priller, Maria Gemenetzi, Anja Schneider, Jens Wiltfang, Emrah Düzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Frederic Brosseron, Marta Marquié, Daniel LA van den Hove, Mercè Boada, Michael T Heneka, Michael Wagner, Natalie Marchant, Jean-Charles Lambert, Ruth Frikke-Schmidt, Frank Jessen, Agustín Ruiz, Alfredo Ramirez

  • Long-term retrieval performance is associated with CA1 hippocampal volume in older adults and individuals at risk for dementia.

    Alzheimer's research & therapy

    Authors: Claudia Bartels, Joy Tzu-Yueh Chen, Michael Belz, Renat Yakupov, Emrah Düzel, Wenzel Glanz, Falk Lüsebrink, Peter Dechent, Luca Kleineidam, Melina Stark, Annika Spottke, Marie Coenjaerts, Klaus Fließbach, Anja Schneider, Ayda Rostamzadeh, Frank Jessen, Björn H Schott, Jens Wiltfang, Ingo Frommann, Michael Wagner, Roberto Goya-Maldonado

  • Perivascular space and white matter hyperintensities in Alzheimer's disease: associations with disease progression and cognitive function.

    Alzheimer's research & therapy

    Authors: Philine Marie Schirge, Robert Perneczky, Toshiaki Taoka, Adriana L Ruiz-Rizzo, Ersin Ersoezlue, Robert Forbrig, Selim Guersel, Carolin Kurz, Matthias Brendel, Julian Hellmann-Regen, Josef Priller, Anja Schneider, Frank Jessen, Emrah Düzel, Katharina Buerger, Stefan Teipel, Christoph Laske, Oliver Peters, Eike Spruth, Klaus Fliessbach, Ayda Rostamzadeh, Wenzel Glanz, Daniel Janowitz, Ingo Kilimann, Sebastian Sodenkamp, Michael Ewers, Boris-Stephan Rauchmann

All publications by Prof. Dr. Anja Schneider