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Prof. Dr. Anja Schneider

Member

Department of Cognitive Disorders and Old Age Psychiatry

anja.schneider@ukbonn.de

Website

My group has focused on fluid biomarkers for the detection of different neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, Frontotemporal Dementia and Amyotrophic Lateral Sclerosis, especially in early, preclinical disease stages. In particular, we are interested in extracellular vesicles, not only as biomarkers but also as modulators of inflammation, their role in cell-cell communication and as potential carriers of disease pathology in neurodegeneration. We are employing data and biomaterial from patient cohorts as well as cell culture and murine models to elucidate the contribution of microglia to disease pathology in Alzheimer’s and Parkinson’s disease.

Recent publications

  • An unsupervised XAI framework for dementia detection with context enrichment.

    Scientific reports

    Authors: Devesh Singh, Yusuf Brima, Fedor Levin, Martin Becker, Bjarne Hiller, Andreas Hermann, Irene Villar-Munoz, Lukas Beichert, Alexander Bernhardt, Katharina Buerger, Michaela Butryn, Peter Dechent, Emrah Düzel, Michael Ewers, Klaus Fliessbach, Silka D Freiesleben, Wenzel Glanz, Stefan Hetzer, Daniel Janowitz, Doreen Görß, Ingo Kilimann, Okka Kimmich, Christoph Laske, Johannes Levin, Andrea Lohse, Falk Luesebrink, Matthias Munk, Robert Perneczky, Oliver Peters, Lukas Preis, Josef Priller, Johannes Prudlo, Diana Prychynenko, Boris S Rauchmann, Ayda Rostamzadeh, Nina Roy-Kluth, Klaus Scheffler, Anja Schneider, Louise Droste Zu Senden, Björn H Schott, Annika Spottke, Matthis Synofzik, Jens Wiltfang, Frank Jessen, Marc-André Weber, Stefan J Teipel, Martin Dyrba

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  • Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Timo Kaleck, Rafael Campos-Martin, Amanda Cano, Maria Victoria Fernández, Pamela Martino-Adami, Luca Kleineidam, Victor M Andrade Fuentes, Kumar P Tripathi, Kayenat Parveen, Raquel Puerta, Itziar de Rojas, Kishore A Ravichandran, Oliver Peters, Julian Hellmann-Regen, Josef Priller, Maria Gemenetzi, Anja Schneider, Jens Wiltfang, Emrah Düzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Frederic Brosseron, Marta Marquié, Daniel LA van den Hove, Mercè Boada, Michael T Heneka, Michael Wagner, Natalie Marchant, Jean-Charles Lambert, Ruth Frikke-Schmidt, Frank Jessen, Agustín Ruiz, Alfredo Ramirez

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  • Long-term retrieval performance is associated with CA1 hippocampal volume in older adults and individuals at risk for dementia.

    Alzheimer's research & therapy

    Authors: Claudia Bartels, Joy Tzu-Yueh Chen, Michael Belz, Renat Yakupov, Emrah Düzel, Wenzel Glanz, Falk Lüsebrink, Peter Dechent, Luca Kleineidam, Melina Stark, Annika Spottke, Marie Coenjaerts, Klaus Fließbach, Anja Schneider, Ayda Rostamzadeh, Frank Jessen, Björn H Schott, Jens Wiltfang, Ingo Frommann, Michael Wagner, Roberto Goya-Maldonado

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