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Prof. Dr. Anne-Katrin Pröbstel

Center for Neurology & Clinic for Neuroimmunology German Center for Neurodegenerative Diseases

Venusberg-Campus 1, 53127 Bonn

anne-katrin.proebstel@ukbonn.de

The work of Anne-Katrin Pröbstel explores the interaction between the immune system and the central nervous system, particularly in the context of neuroinflammatory and neurodegenerative diseases. She is also interested in decoding the complex interactions between the microbiota and the immune system. Her research explores the mechanisms by which immune cells, especially B cells and antibodies, contribute to neuroinflammation and neuronal damage. By using advanced techniques such as single-cell sequencing, immune repertoire analysis, and gnotobiotic mouse models, she aims to uncover critical biomarkers and therapeutic targets to advance precision medicine in neurology.

Prof. Dr. Pröbstel

Recent publications

  • OCT-Based Differentiation of First Acute Optic Neuritis: An International Study of 111 Patients With NMOSD and MOGAD.

    Neurology(R) neuroimmunology & neuroinflammation

    Authors: Thivya Pakeerathan, James Davis, Amanda D Henderson, Elias S Sotirchos, Yana Said, Joachim Havla, Marius Ringelstein, Orhan Aktas, Margit Weise, Jonathan A Gernert, Barbara Kornek, Gabriel Bsteh, Paulus S Rommer, Nik Krajnc, Anne-Katrin Pröbstel, Athina Papadopoulou, Laila Kulsvehagen, Roxanne Pretzsch, Kean Schoenholzer, Tanyatuth Padungkiatsagul, Heather E Moss, Sylvia E Villarreal Navarro, Marina Herwerth, Madalina Graure, Veronika Kana, Hadas Stiebel-Kalish, Rita Zlatkin, Anthony C Arnold, Laura Bonelli, Jan-Patrick Stellmann, Natacha Stolowy, Carolin Schwake, Christiane Schneider-Gold, Tania Kümpfel, Philipp Albrecht, Natthapon Rattanathamsakul, Sean J Pittock, Eoin P Flanagan, Sara Carta, Sara Mariotto, Ralf Gold, John J Chen, Ilya Ayzenberg

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  • Lymphotoxin-dependent elevated meningeal CXCL13:BAFF ratios drive gray matter injury.

    Nature immunology

    Authors: Ikbel Naouar, Andrei Pangan, Michelle Zuo, Syed Ali Raza, Kevin Champagne-Jorgensen, Jyot Patel, Angela Wang, Annie Pu, Lesley Ward, Jennifer S Y Ahn, Faizah N Sayeed, Jingwen Zhu, Elisabeth Pössnecker, Shoshana Spring, John G Sled, Bruno Cenni, Barbara Nuesslein-Hildesheim, Jeffrey L Browning, Anne-Katrin Pröbstel, Daniel S Reich, Jennifer L Gommerman, Valeria Ramaglia

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  • Immunotherapies in progressive multiple sclerosis.

    Handbook of clinical neurology

    Authors: Tradite Neziraj, Ludwig Kappos, Anne-Katrin Pröbstel

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