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Prof. Dr. Anne-Katrin Pröbstel

Center for Neurology & Clinic for Neuroimmunology German Center for Neurodegenerative Diseases

Venusberg-Campus 1, 53127 Bonn

anne-katrin.proebstel@ukbonn.de

The work of Anne-Katrin Pröbstel explores the interaction between the immune system and the central nervous system, particularly in the context of neuroinflammatory and neurodegenerative diseases. She is also interested in decoding the complex interactions between the microbiota and the immune system. Her research explores the mechanisms by which immune cells, especially B cells and antibodies, contribute to neuroinflammation and neuronal damage. By using advanced techniques such as single-cell sequencing, immune repertoire analysis, and gnotobiotic mouse models, she aims to uncover critical biomarkers and therapeutic targets to advance precision medicine in neurology.

Prof. Dr. Pröbstel

Recent publications

  • The gut microbiota plays a modifiable role in MS progression-YES.

    Multiple sclerosis (Houndmills, Basingstoke, England)

    Authors: Moschoula Passali, Gurumoorthy Krishnamoorthy, Anne-Katrin Pröbstel

  • Evaluation of Dried Plasma Spot-Based Quantification of Glial Fibrillary Acidic Protein as a Disease-Associated Biomarker in Neuromyelitis Optica Spectrum Disorder.

    Annals of clinical and translational neurology

    Authors: Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S Sperber, Tanja Schmitz-Hübsch, Frederike C Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne-Katrin Pröbstel, Xiao-Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul

  • Anti-CD20 B cell depletion is associated with elevated mucosal-originating circulating regulatory IgA B cells in multiple sclerosis.

    Science translational medicine

    Authors: Tradite Neziraj, Elisabeth Pössnecker, Angela A Wang, Paul Saary, Adrian-Minh Schumacher, Florian Ingelfinger, Amandine Mathias, Edoardo Galli, Marco Häfelfinger, Michelle Zuo, Samuel Jones, Vasiliki Pantazou, Joep Killestein, Sabine Schädelin, Pascal Benkert, Cristina Granziera, Caroline Pot, Antje Bischof, Jan Hendrik Niess, Magdalena Filipowicz Sinnreich, Tobias Derfuss, Charlotte E Teunissen, Jens Kuhle, David A Hafler, Renaud Du Pasquier, Yoshiaki Yasumizu, Jennifer L Gommerman, Anne-Katrin Pröbstel

All publications by Prof. Dr. Anne-Katrin Pröbstel