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Prof. Dr. Annkristin Heine

Member, Steering-Committee Member

Institute of Experimental Immunology (IEI) & Medical Clinic III

Medical Faculty, University of Bonn University Hospital of Bonn Venusberg - Campus 1 53127 Bonn

annkristin.heine@ukbonn.de

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Dr. Heine and her group are interested in the mechanisms governing antigen cross-presentation and cytotoxic T cell induction in the context of anti-tumor immune responses. Effective cancer vaccines should not only induce strong and durable T cell responses, but also optimally modulate the balance between suppressive and stimulatory factors in the tumor microenvironment. The aim of her research is the identification of novel immunotherapeutic strategies that accomplish both, with a special focus on different pathways of dendritic cell licensing and chemokine receptor modulation.

Annkristin Heine

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Recent publications

  • CD103+ tissue-resident T-cells in head and neck squamous cell carcinomas of patients treated anti-PD-1 therapy.

    Cancer treatment and research communications

    Authors: Christine Sanders, Dahlia Kittel, Annkristin Heine, Sebastian Strieth, Tessa Hattenhauer, Rebekka Mispelbaum, Dimo Dietrich, Glen Kristiansen, Peter Brossart, Marieta Ioana Toma

  • Inhibition of Fibroblast Growth Factor Receptor 3 Signaling by Ponatinib Reduces Growth and Cytokine Production of Multiple Myeloma Cells.

    International journal of molecular sciences

    Authors: Sascha Kampmann, Sebastian Schlaweck, Benjamin V Becker, Chrystel Flores, Annkristin Heine, Peter Brossart, Stefanie A E Held

  • Clinical efficacy and immunological aspects of neoadjuvant and perioperative therapy in resectable head and neck carcinoma.

    Cancer treatment reviews

    Authors: Tessa Hattenhauer, Rebekka Mispelbaum, Franz-Georg Bauernfeind, Georg Feldmann, Dirk Baumjohann, Johannes Brägelmann, Annkristin Heine, Peter Brossart

All publications by Prof. Dr. Annkristin Heine