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Prof. Dr. Annkristin Heine

Member, Steering-Committee Member

Institute of Experimental Immunology (IEI) & Medical Clinic III

Medical Faculty, University of Bonn University Hospital of Bonn Venusberg - Campus 1 53127 Bonn

annkristin.heine@ukbonn.de

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Dr. Heine and her group are interested in the mechanisms governing antigen cross-presentation and cytotoxic T cell induction in the context of anti-tumor immune responses. Effective cancer vaccines should not only induce strong and durable T cell responses, but also optimally modulate the balance between suppressive and stimulatory factors in the tumor microenvironment. The aim of her research is the identification of novel immunotherapeutic strategies that accomplish both, with a special focus on different pathways of dendritic cell licensing and chemokine receptor modulation.

Annkristin Heine

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Recent publications

  • Mosunetuzumab as salvage therapy for refractory connective tissue diseases: clinical responses and immunological insights.

    Annals of the rheumatic diseases

    Authors: Lea Bischof, Raquel Lorenzetti, David Kickinger, Sonja Kreuzer, Marea Cialimbruschi, Barbara Dreo, Fotini Rosi Vagena, Jasminka Igrec, Holger Flick, Marie Rüthing, Ulrike Strube, Susanne V Schmidt, Martin Stradner, Ruth Breszinsek, Annkristin Heine, Jens Thiel, Julia Höbart, Selina J Keppler

  • Characterisation of TP53 mutational features and outcomes of acute myeloid leukaemia after allogeneic haematopoietic cell transplantation.

    Bone marrow transplantation

    Authors: Martina Reuss, Thomas Meyer, Florian Ingelfinger, Rouven Hoefflin, Miriam Mozaffari Jovein, Hosna Baniadam, Dietmar Pfeifer, Justus Duyster, Jesus Duque-Afonso, Kristina Maas-Bauer, Ralph Wäsch, Armin Zebisch, Annkristin Heine, Tobias Holderried, Jürgen Finke, Claudia Wehr, Robert Zeiser, Tobias Wertheimer

  • CD103+ tissue-resident T-cells in head and neck squamous cell carcinomas of patients treated anti-PD-1 therapy.

    Cancer treatment and research communications

    Authors: Christine Sanders, Dahlia Kittel, Annkristin Heine, Sebastian Strieth, Tessa Hattenhauer, Rebekka Mispelbaum, Dimo Dietrich, Glen Kristiansen, Peter Brossart, Marieta Ioana Toma

All publications by Prof. Dr. Annkristin Heine