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Prof. Dr. Axel Kallies

Member

Institute of Molecular Medicine and Experimental Immunology (IMMEI)

Venusberg-Campus 1, 53127 Bonn

axel.kallies@unimelb.edu.au

The research of the Kallies lab focusses on T cell differentiation and function in viral infection, cancer and metabolic disease. Specifically, we aim to understand the molecular regulation of cytotoxic CD8 T cells, conventional CD4 T cells and regulatory T cells with a focus on stem-like and tissue-resident cells in chronic disease. We make extensive use of preclinical models and cutting-edge technology such as single cell RNA sequencing and epigenetic profiling.

Prof. Dr. Axel Kallies

Recent publications

  • Guidelines for T cell nomenclature.

    Nature reviews. Immunology

    Authors: David Masopust, Amit Awasthi, Rémy Bosselut, David G Brooks, Marcus Buggert, Kenji Chamoto, Weiguo Cui, Chen Dong, Donna L Farber, Thomas Gebhardt, Carmen Gerlach, Ananda Goldrath, Philip D Greenberg, J Scott Hale, Adrian Hayday, Dirk Homann, Matteo Iannacone, Stephen C Jameson, Marc K Jenkins, Nikhil S Joshi, Susan M Kaech, Axel Kallies, Alice O Kamphorst, Mark H Kaplan, Paul Klenerman, Marco Künzli, Antonio Lanzavecchia, Georg M Lauer, Enrico Lugli, Andrew D Luster, Laura K Mackay, M Juliana McElrath, Scott N Mueller, Zaza Ndhlovu, Thumbi Ndung'u, Pamela S Ohashi, Annette Oxenius, Giuseppe Pantaleo, Marion Pepper, Louis J Picker, Clare F Quarnstrom, Gustavo Reyes-Terán, Mario Roederer, Pamela C Rosato, Gonzalo Salgado-Montes de Oca, Federica Sallusto, Ton N Schumacher, Daniella M Schwartz, Eui-Cheol Shin, Andrew G Soerens, Daniela S Thommen, Vaiva Vezys, João P B Viola, Bruce D Walker, Tania H Watts, Casey T Weaver, E John Wherry, Hai-Hui Xue, Ben Youngblood, Rafi Ahmed

  • Stem-like tissue-resident memory T cells control functional heterogeneity and reactivation of T cell memory in the intestine.

    Science immunology

    Authors: Kevin Man, Vinicius A Duarte da Silva, Nikita Potemkin, Sarah S Gabriel, Teisha Mason, Tarek Elmzzahi, Marcela De Lima Moreira, Chun-Hsi Su, Laura Mackay, Marc D Beyer, Jan Schröder, Georg Gasteiger, Axel Kallies

  • Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer.

    Nature immunology

    Authors: Leonie Heyden, Lisa Rausch, Michael H Shannon, Lachlan Dryburgh, Marcela L Moreira, Aleksej Frolov, Christina M Scheffler, Marit J van Elsas, Junming Tong, Olivia Hidajat, Sharanya K M Wijesinghe, Sining Li, Helena Horvatic, Nhat Truong Huynh-Anh, Catarina Gago da Graça, Carlson Tsui, Maren Köhne, Daniel Sommer, F Thomas Wunderlich, Bianca von Scheidt, Simone L Park, Laura K Mackay, Daniel T Utzschneider, Jan Schröder, Stephen J Turner, Phillip K Darcy, Marc D Beyer, Zeinab Abdullah, Axel Kallies

All publications by Prof. Dr. Axel Kallies