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Prof. Dr. Christian Bode

Member

Clinic for Anesthesiology and Operative Intensive Medicine

Venusberg-Campus 1, 53127 Bonn

christian.bode@ukbonn.de

+49 228 28114119

Our research focuses on the molecular and cellular mechanisms underlying immune responses in inflammatory diseases of critical ill patients, including Systemic Inflammatory Response Syndrome (SIRS), sepsis, and Acute Respiratory Distress Syndrome (ARDS). Through a translational approach, we explore the regulation of the innate immune response, particularly how danger- and pathogen-associated molecular patterns (DAMPs and PAMPs) are recognized and how their activated signaling pathways can be modulated. A key aspect of our work is understanding the variability of individual immune responses, with the ultimate goal of developing personalized treatments to prevent and manage organ failure in the context of critical illness.

Prof. Dr. Christian Bode

Recent publications

  • Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.

    Intensive care medicine experimental

    Authors: Sascha David, Marc Leone, Massimo Girardis, Mattia M Müller, Srdjan Gavrilovic, Roberta Domizi, Elisa Damiani, Ignacio Martin-Loeches, Ricard Ferrer, Christian Bode, Benjamin Chousterman, Lene Russell

  • "Effect of weight-based versus absolute norepinephrine dosing on mortality risk in obese patients with septic shock: an observational, multicohort, retrospective study".

    Anesthesiology

    Authors: Pedro D Wendel-Garcia, Sebastian Morales, Sascha David, Miguel Ibarra-Estrada, Christian Jung, Reto A Schuepbach, Ricardo Castro, Jaime Retamal, Antonio Messina, Giovanni Camen, Christian Bode, Luis I Cortínez, Nicolás Severino, Philipp Karl Buehler, Niklas Rodemund, Greta Emilia Kiavialaitis, Edda Tschernko, Gustavo A Ospina-Tascón, Jan Bakker, Glenn Hernández, Eduardo Kattan

  • [The latest SOFA score update: a balancing act between ambition and reality].

    Die Anaesthesiologie

    Authors: Philippe Kruse, Christian Bode

All publications by Prof. Dr. Christian Bode