Demographics and outcome of Legionella pneumonia in the intensive care unit: a retrospective multicenter cohort study.
Critical care (London, England)
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Venusberg-Campus 1, 53127 Bonn
Our research focuses on the molecular and cellular mechanisms underlying immune responses in inflammatory diseases of critical ill patients, including Systemic Inflammatory Response Syndrome (SIRS), sepsis, and Acute Respiratory Distress Syndrome (ARDS). Through a translational approach, we explore the regulation of the innate immune response, particularly how danger- and pathogen-associated molecular patterns (DAMPs and PAMPs) are recognized and how their activated signaling pathways can be modulated. A key aspect of our work is understanding the variability of individual immune responses, with the ultimate goal of developing personalized treatments to prevent and manage organ failure in the context of critical illness.
Critical care (London, England)
View this publicationMedizinische Klinik, Intensivmedizin und Notfallmedizin
View this publicationDie Anaesthesiologie
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