Skip to main content

Prof. Dr. Christian Bode

Member

Clinic for Anesthesiology and Operative Intensive Medicine

Venusberg-Campus 1, 53127 Bonn

christian.bode@ukbonn.de

+49 228 28114119

Our research focuses on the molecular and cellular mechanisms underlying immune responses in inflammatory diseases of critical ill patients, including Systemic Inflammatory Response Syndrome (SIRS), sepsis, and Acute Respiratory Distress Syndrome (ARDS). Through a translational approach, we explore the regulation of the innate immune response, particularly how danger- and pathogen-associated molecular patterns (DAMPs and PAMPs) are recognized and how their activated signaling pathways can be modulated. A key aspect of our work is understanding the variability of individual immune responses, with the ultimate goal of developing personalized treatments to prevent and manage organ failure in the context of critical illness.

Prof. Dr. Christian Bode

Recent publications

  • Lack of S100A8 impairs lung protective immunity against Streptococcus pneumoniae.

    The Journal of infectious diseases

    Authors: Lena Ostermann, Benjamin Seeliger, Konrad Peukert, Lara-Kristin Steinmetz, Carolin Flasche, Regina Maus, Jennifer Stolper, Thomas Vogl, Andreas Pich, Christian Bode, Konstantin Neumann, Korbinian Brand, Philippe A Tessier, Johannes Roth, Ulrich A Maus

  • Knowledge gaps in extracorporeal blood purification: what would be required for its successful application in septic shock?

    Intensive care medicine experimental

    Authors: Sascha David, Thomas Rimmelé, Michael Joannidis, Massimo Girardis, Peter Pickkers, Nathan D Nielsen, Alix Buhlmann, Zsolt Molnar, Marlies Ostermann, Jan T Kielstein, Pedro David Wendel-Garcia, Christian Bode, Klaus Stahl

  • A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial.

    Lancet (London, England)

    Authors: Alexander Zarbock, Marlies Ostermann, Lui Forni, Christian Bode, Lennart Wild, Christian Putensen, Diego Parise Roux, Elena Elías Martín, Christian Arndt, Tim Rahmel, Silvia de Rosa, Céline Monard, Antoine G Schneider, Adam Glass, Mona Jung-König, Stefano Romagnoli, James Gossage, Nuttha Lumlertgul, Jan Gerrit Haaker, Javier Ripollés-Melchor, Savino Spadaro, Antonio Siniscalchi, Emmanuel Futier, Lucie Aupetitgendre, Irene Romero Bhathal, Raquel García Álvarez, Alice Bernard, Peter Rosenberger, Carola Wempe, Mahan Sadjadi, Melanie Meersch, Karen Fischhuber, Rinaldo Bellomo, John A Kellum, Thilo von Groote

All publications by Prof. Dr. Christian Bode