Skip to main content

Prof. Dr. Christian Bode

Member

Clinic for Anesthesiology and Operative Intensive Medicine

Venusberg-Campus 1, 53127 Bonn

christian.bode@ukbonn.de

+49 228 28114119

Our research focuses on the molecular and cellular mechanisms underlying immune responses in inflammatory diseases of critical ill patients, including Systemic Inflammatory Response Syndrome (SIRS), sepsis, and Acute Respiratory Distress Syndrome (ARDS). Through a translational approach, we explore the regulation of the innate immune response, particularly how danger- and pathogen-associated molecular patterns (DAMPs and PAMPs) are recognized and how their activated signaling pathways can be modulated. A key aspect of our work is understanding the variability of individual immune responses, with the ultimate goal of developing personalized treatments to prevent and manage organ failure in the context of critical illness.

Prof. Dr. Christian Bode

Recent publications

  • Intestinal fatty acid-binding protein (I-FABP) at ICU admission as early biomarker of intestinal injury and predictor of mortality in septic shock.

    Intensive care medicine experimental

    Authors: Thorben Pape, Pedro David Wendel-Garcia, Nina Rittgerodt, Bahar Nalbant, Jan Hinrichs, Lena S Becker, Anna M Hunkemöller, Jakob Raith, Sören K J Boblitz, Jannik Ruwisch, Pia-Victoria Fangmann, Heiner Wedemeyer, Marius M Hoeper, Christian Bode, Sascha David, Klaus Stahl, Benjamin Seeliger

  • [Pharmacological immunomodulation in sepsis].

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    Authors: Christian Bode

  • Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.

    Intensive care medicine experimental

    Authors: Sascha David, Marc Leone, Massimo Girardis, Mattia M Müller, Srdjan Gavrilovic, Roberta Domizi, Elisa Damiani, Ignacio Martin-Loeches, Ricard Ferrer, Christian Bode, Benjamin Chousterman, Lene Russell

All publications by Prof. Dr. Christian Bode