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Prof. Dr. Christian Bode

Member

Clinic for Anesthesiology and Operative Intensive Medicine

Venusberg-Campus 1, 53127 Bonn

christian.bode@ukbonn.de

+49 228 28114119

Our research focuses on the molecular and cellular mechanisms underlying immune responses in inflammatory diseases of critical ill patients, including Systemic Inflammatory Response Syndrome (SIRS), sepsis, and Acute Respiratory Distress Syndrome (ARDS). Through a translational approach, we explore the regulation of the innate immune response, particularly how danger- and pathogen-associated molecular patterns (DAMPs and PAMPs) are recognized and how their activated signaling pathways can be modulated. A key aspect of our work is understanding the variability of individual immune responses, with the ultimate goal of developing personalized treatments to prevent and manage organ failure in the context of critical illness.

Prof. Dr. Christian Bode

Recent publications

  • Effect of therapeutic plasma exchange on acquired hypocholesterolemia in patients with septic shock: a post hoc analysis of the two exchange trials.

    Critical care (London, England)

    Authors: Thorben Pape, Daniel A Hofmaenner, Dorothea M Heuberger, Ralf Lichtinghagen, Korbinian Brand, Heiko Schenk, Christian Putensen, Benjamin Seeliger, Christian Bode, Klaus Stahl, Sascha David

  • [Precision immunotherapy improves organ dysfunction in sepsis].

    Die Anaesthesiologie

    Authors: Lennart Wild, Christian Bode

  • Lack of S100A8 impairs lung protective immunity against Streptococcus pneumoniae.

    The Journal of infectious diseases

    Authors: Lena Ostermann, Benjamin Seeliger, Konrad Peukert, Lara-Kristin Steinmetz, Carolin Flasche, Regina Maus, Jennifer Stolper, Thomas Vogl, Andreas Pich, Christian Bode, Konstantin Neumann, Korbinian Brand, Philippe A Tessier, Johannes Roth, Ulrich A Maus

All publications by Prof. Dr. Christian Bode