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Prof. Dr. Elvira Mass

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

elvira.mass@uni-bonn.de

+49 228 7362848

Website

Our group has the overarching aim to characterise the role of fetal-derived resident macrophages for organ development and function and how genetic and epigenetic perturbations can influence their homeostatic and immune functions. To achieve this, we are using genetic mouse models and human organoid cultures in combination with omics (transcriptome, proteome, lipidome, surfaceome). The ultimate goal is to describe novel mechanisms leading to metabolic and degenerativedisorders and define preventative measures targeting macrophages.

Elvira Mass

Recent publications

  • Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism.

    Nature metabolism

    Authors: Nikola Makdissi, Maria Francesca Viola, Lisa Maria Steinheuer, Nelli Blank-Stein, Ronja Kardinal, Fabrizio Musacchio, Eliana Franco Taveras, Virginia Aliprandi, Katharina Sieckmann, Akram Abdulkadyrov, Marina L Mayer, Marie-Louise Diefenbach-Wilke, Diana Fink, Hannes Beckert, Stefan Böhmdorfer, Quentin Deveuve, Frederike J Graelmann, Katharina Mauel, Nele Kronau, Jake Thomas, David Bejarano, Andreas Schlitzer, Sandra Högler, Mohamed H Yaghmour, Joerg Heeren, Christoph Thiele, Lukas Kenner, Felix Meissner, Falk Nimmerjahn, Martin Fuhrmann, Dagmar Wachten, Kevin Thurley, Elvira Mass

  • Canonical Notch2 signaling regulates development and maintenance of iron-recycling macrophages and iron homeostasis.

    Nature communications

    Authors: Frauline Nicole Schroth, Tamar Kapanadze, Stefan Sablotny, Yuangao Xu, Alessia Ascierto, Matthias Ballmaier, Katharina Mauel, Bo Mee Chung, Lena Deuper, Andrey S Shaw, Andreas Kispert, Matthias Lochner, Tibor Kempf, Elvira Mass, Hermann Haller, Kai M Schmidt-Ott, Jaba Gamrekelashvili, Florian P Limbourg

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

All publications by Prof. Dr. Elvira Mass