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Prof. Dr. Elvira Mass

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

elvira.mass@uni-bonn.de

+49 228 7362848

Website

Our group has the overarching aim to characterise the role of fetal-derived resident macrophages for organ development and function and how genetic and epigenetic perturbations can influence their homeostatic and immune functions. To achieve this, we are using genetic mouse models and human organoid cultures in combination with omics (transcriptome, proteome, lipidome, surfaceome). The ultimate goal is to describe novel mechanisms leading to metabolic and degenerativedisorders and define preventative measures targeting macrophages.

Elvira Mass

Recent publications

  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

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  • Maternal diet shapes the development and identity of tissue-resident macrophages.

    Trends in immunology

    Authors: Hao Huang, Elvira Mass

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  • Characterization of the mammalian prodefinitive angio-hematopoietic lineage.

    Science immunology

    Authors: Tomi Lazarov, Pierre-Louis Loyher, Hairu Yang, Zi-Ning Choo, Zihou Deng, Sonja Nowotschin, Ying-Yi Kuo, Ting Zhou, Araitz Alberdi-Gonzalez, Ralf Stumm, Elvira Mass, Elisa Gomez Perdiguero, Anna-Katerina Hadjantonakis, Frederic Geissmann

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