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Prof. Dr. Elvira Mass

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

elvira.mass@uni-bonn.de

+49 228 7362848

Website

Our group has the overarching aim to characterise the role of fetal-derived resident macrophages for organ development and function and how genetic and epigenetic perturbations can influence their homeostatic and immune functions. To achieve this, we are using genetic mouse models and human organoid cultures in combination with omics (transcriptome, proteome, lipidome, surfaceome). The ultimate goal is to describe novel mechanisms leading to metabolic and degenerativedisorders and define preventative measures targeting macrophages.

Elvira Mass

Recent publications

  • BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.

    The EMBO journal

    Authors: Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Seniz Yüksel, Ronja Kardinal, Lisa Maria Steinheuer, Fabian Frechen, Luis Henrique Corrêa, Geza Schermann, Christina Klausen, Nelli Blank-Stein, Jonas Schulte-Schrepping, Collins Osei-Sarpong, Matthias Becker, Lorenzo Bonaguro, Marc Beyer, Helen Louise May-Simera, Jelena Zurkovic, Christoph Thiele, Kevin Thurley, Lydia Sorokin, Carmen Ruiz de Almodovar, Elvira Mass, Dagmar Wachten

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  • A single-cell atlas to map sex-specific gene-expression changes in blood upon neurodegeneration.

    Nature communications

    Authors: Friederike Grandke, Tobias Fehlmann, Fabian Kern, David M Gate, Tobias William Wolff, Olivia Leventhal, Divya Channappa, Pascal Hirsch, Edward N Wilson, Eckart Meese, Chuanyu Liu, Quan Shi, Matthias Flotho, Yongping Li, Cynthia Chen, Yeya Yu, Jiangshan Xu, Michael Junkin, Zhifeng Wang, Tao Wu, Longqi Liu, Yong Hou, Katrin I Andreasson, Jenny S Gansen, Elvira Mass, Kathleen Poston, Tony Wyss-Coray, Andreas Keller

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  • Bacterial translocation promotes trained immunity.

    Immunity

    Authors: Maria Francesca Viola, Elvira Mass

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