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Prof. Dr. med. Jörg Kalff

Member

Department of Surgery

Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53127 Bonn

kalff@uni-bonn.de

+49 228 28715214

Website

The focus of research are the immunological consequences of operative trauma and their recognition and regulation in post-operative dysfunction of the gastrointestinal tract. The group described and elucidated the immunological pathomechanism of postoperative ileus. Furthermore, the group found that the gastrointestinal field effect - a panenteric inflammation following localized abdominal surgery - is mediated by an immunological response involving resident intestinal macrophages, mesenteric dendritic cells and memory TH1 cells.

Recent publications

  • Towards clinically interpretable machine learning in emergency surgery: feature importance and insights across clinical time points in abdominal pain cases.

    Langenbeck's archives of surgery

    Authors: Jonas Henn, Simon Hatterscheidt, Svetozar Nesic, Sebastian Nowak, Wolfgang Block, Johannes Röttgen, Ingo Gräff, Jörg C Kalff, Alois M Sprinkart, Andreas Buness, Hanno Matthaei

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  • [Evaluation of Multimodal Perioperative Care Pathway Supported by a Patient-facing Mobile App in Colorectal Surgery - First Clinical Experience and Patient Satisfaction].

    Zentralblatt fur Chirurgie

    Authors: Mona Breßer, Charlotte Wiedemann, Nils Sommer, Ambra Marx, Paula Tups, Hannah Schulz, Jörg C Kalff, Tim Vilz, Jonas Dohmen

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  • Mast cell activation within the mesentery depends on vagal signaling following abdominal surgery.

    Surgery open science

    Authors: Anna Woestemeier, Timo Schwandt, Philipp Lingohr, Mariola Lysson, Sven Wehner, Jörg C Kalff, Gun-Soo Hong

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