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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • BCG-induced trained immunity potentiates TH17 responses in vitro.

    Journal of leukocyte biology

    Authors: Leonie S Helder, Laszlo A Groh, Vasiliki Matzaraki, Rob Ter Horst, Gert Jan Scheffer, Leo A B Joosten, Mihai G Netea, Anaísa V Ferreira

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  • Can metaphors in patient information materials improve comprehension and attitudes regarding innovative treatment? The case of personalized immunotherapy for sepsis.

    Patient education and counseling

    Authors: Nynke Bos, W Gudrun Reijnierse, Anke J M Oerlemans, Frank L van de Veerdonk, Mihai G Netea, Marlies E J L Hulscher, Lisa Vandeberg

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  • The long-term effect of metabolic bariatric surgery on innate immune cell phenotype and function.

    International journal of obesity (2005)

    Authors: Julia van Tuijl, Debby Vreeken, Wieteke Broeders, Benjamin Cossins, Liesbeth van Emst, Florine Seidel, Rinke Stienstra, Yang Li, Leo A B Joosten, Mihai G Netea, Eric J Hazebroek, Robert Kleemann, Amanda J Kiliaan, Siroon Bekkering, Niels P Riksen

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