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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Mihai Netea

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Recent publications

  • Genetic and non-genetic drivers of platelet reactivity in healthy Tanzanian individuals.

    Journal of thrombosis and haemostasis : JTH

    Authors: Vesla I Kullaya, Godfrey S Temba, Nadira Vadaq, Judith Njau, Collins K Boahen, Bongani B Nkambule, Florian Thibord, Ming-Huei Chen, Tal Pecht, Furaha Lyamuya, Vinod Kumar, Mihai G Netea, Blandina T Mmbaga, Andre van der Ven, Andrew D Johnson, Quirijn de Mast

  • Acid ceramidase regulates innate immune memory.

    Cell reports

    Authors: Nils Rother, Cansu Yanginlar, Geoffrey Prévot, Inge Jonkman, Maaike Jacobs, Mandy M T van Leent, Julia van Heck, Vasiliki Matzaraki, Anthony Azzun, Judit Morla-Folch, Anna Ranzenigo, William Wang, Roy van der Meel, Zahi A Fayad, Niels P Riksen, Luuk B Hilbrands, Rik G H Lindeboom, Joost H A Martens, Michiel Vermeulen, Leo A B Joosten, Mihai G Netea, Willem J M Mulder, Johan van der Vlag, Abraham J P Teunissen, Raphaël Duivenvoorden

  • Fatty acid desaturation and lipoxygenase pathways support trained immunity.

    Nature communications

    Authors: Anaísa V Ferreira, Juan Carlos Alarcon-Barrera, Jorge Domínguez-Andrés, Özlem Bulut, Gizem Kilic, Priya A Debisarun, Rutger J Röring, Hatice N Özhan, Eva Terschlüsen, Athanasios Ziogas, Sarantos Kostidis, Yassene Mohammed, Vasiliki Matzaraki, George Renieris, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Martin Giera

All publications by Prof. Dr. Mihai Netea