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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Deciphering cross-cohort metabolic signatures of immune responses and their implications for disease pathogenesis.

    Molecular systems biology

    Authors: Jianbo Fu, Nienke van Unen, Andrei Sarlea, Nhan Nguyen, Martin Jaeger, Javier Botey Bataller, Valerie A C M Koeken, L Charlotte de Bree, Vera P Mourits, Simone J C F M Moorlag, Godfrey Temba, Vesla I Kullaya, Quirijn de Mast, Leo A B Joosten, Cheng-Jian Xu, Mihai G Netea, Yang Li

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  • Maladaptive trained immunity in viral infections.

    The Journal of clinical investigation

    Authors: Dmitri Sviridov, Mihai G Netea, Michael I Bukrinsky

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  • BCG-induced trained immunity potentiates TH17 responses in vitro.

    Journal of leukocyte biology

    Authors: Leonie S Helder, Laszlo A Groh, Vasiliki Matzaraki, Rob Ter Horst, Gert Jan Scheffer, Leo A B Joosten, Mihai G Netea, Anaísa V Ferreira

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