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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Mihai Netea

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Recent publications

  • TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size.

    Nature immunology

    Authors: Khader Ghneim, Felipe Ten-Caten, Ana Carolina Santana, Muhammad Bilal Latif, Diego Andres Diaz-Dinamarca, Tamara García-Salum, Perla Mariana Del Rio Estrada, Puja Sohal, Zachary Strongin, Justin Harper, Sherrie Jean, Chelsea Wallace, Robert Balderas, Jeffrey D Lifson, Gopalan Raghunathan, Eric Rimmer, Cinthia V Pastuskovas, Guoxin Wu, Luca Micci, Luiz Felipe Martins Sieben, Pedro Cesar Lopes Gerum, Jessica Dos Santos, Mihai G Netea, Andre van der Ven, Guido Silvestri, Daria J Hazuda, Daniel M Gorman, Bonnie J Howell, Ashish A Sharma, Mirko Paiardini, Hugo Soudeyns, Susan Pereira Ribeiro, Rafick P Sekaly

  • Sex-stratified genetic regulators of cytokine production in the Dutch and Tanzanian populations.

    HGG advances

    Authors: Caroline Amour, Raul Cetatean, Isis Ricano Ponce, Nick Keur, Godfrey S Temba, Vesla I Kullaya, Blandina T Mmbaga, Reginald Kavishe, Leo A B Joosten, Mihai G Netea, Quirijn de Mast, Collins K Boahen, Vinod Kumar

  • Identification of a robust metabolic signature associated with hospital-acquired pneumonia and response to interferon-gamma treatment in critically ill patients.

    Critical care (London, England)

    Authors: Melanie Petrier, Debajyoti Sinha, Florian P Martin, Cecile Poulain, Delphine Flattres Duchaussoy, Athanasios Ziogas, Boris Novakovic, Laura Hurtado-Navarro, Anaísa V Ferreira, Joost H A Martens, Despoina Koulenti, Laia Fernández-Barat, Antoni Torres, Emmanuel Montassier, Mihai G Netea, Jeremie Poschmann, Antoine Roquilly

All publications by Prof. Dr. Mihai Netea