Phenotypic and epigenetic profiles of circulating NK cells in spontaneous HIV-1 controllers.
EBioMedicine
View this publicationMember, Steering-Committee Member
University of Bonn Carl-Troll-Strasse 31 53115 Bonn
The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.
EBioMedicine
View this publicationProceedings of the National Academy of Sciences of the United States of America
View this publicationNature reviews. Nephrology
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