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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Mihai Netea

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Recent publications

  • Trained immunity: induction of an inflammatory memory in disease.

    Cell research

    Authors: Titus Schlüter, Yuri van Elsas, Bram Priem, Athanasios Ziogas, Mihai G Netea

  • Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk.

    Molecular omics

    Authors: Kieu T T Le, Nick Keur, Heleen Middelkamp, Thuy Linh Do, Albert van den Berg, Valeria Orlova, Leo A B Joosten, Mihai G Netea, Cisca Wijmenga, Iris Jonkers, Sebo Withoff, Andries D Van der Meer, Vinod Kumar

  • The impact of interferon-γ pathway on trained immunity induction by vaccination with Bacille Calmette-Guérin.

    Scientific reports

    Authors: Ekaterina Isachesku, Andrei Cismaru, Vasiliki Matzaraki, Simone J C F M Moorlag, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Leo A B Joosten, Ioana Berindan-Neagoe, Mihai G Netea

All publications by Prof. Dr. Mihai Netea