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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Phenotypic and epigenetic profiles of circulating NK cells in spontaneous HIV-1 controllers.

    EBioMedicine

    Authors: Alisa Huber, Albert L Groenendijk, Adriana Navas, Nadira Vadaq, Suzanne D E Ruijten, Vasiliki Matzaraki, Ezio T Fok, Aysel Gurbanova, Wilhelm A J W Vos, Marc J T Blaauw, Louise E van Eekeren, Maartje C P Jacobs-Cleophas, Janneke Stalenhoef, Marvin Berrevoets, Renate van der Molen, Arnold van der Meer, Marien I de Jonge, Joost H A Martens, Casper Rokx, Annelies Verbon, Jan van Lunzen, Hans J P M Koenen, Mihai G Netea, Andre J A M van der Ven, Leo A B Joosten, Jéssica C Dos Santos

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  • Glycan microarray analysis of -related antibodies in human and mice sera guides biomarker discovery and vaccine development.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Emelie E Reuber, Emer Hickey, Arnab Pradhan, Rosanne Sprute, Tilman Lingscheid, Pinkus Tober-Lau, Ian Leaves, Mark H T Stappers, Florian Kurth, Mariolina Bruno, Mihai G Netea, Leif E Sander, Oliver A Cornely, Neil A R Gow, Alistair J P Brown, Rajat K Singh, Sabrina Omoregbee-Leichnitz, Eric T Sletten, José Danglad-Flores, Peter H Seeberger

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  • The immunology of sepsis: translating new insights into clinical practice.

    Nature reviews. Nephrology

    Authors: Matthijs Kox, Michael Bauer, Lieuwe D J Bos, Hjalmar Bouma, Thierry Calandra, Carolyn S Calfee, Benjamin G Chousterman, Lennie P G Derde, Evangelos J Giamarellos-Bourboulis, Hernando Gómez, Mihai G Netea, Marlies Ostermann, Tom van der Poll, Brendon P Scicluna, Christopher Seymour, Manu Shankar-Hari, Nathan Shapiro, Mervyn Singer, Fabienne Venet, Alexander P J Vlaar, Lonneke A van Vught, Sebastian Weis, W Joost Wiersinga, Peter Pickkers

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