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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • HIV immunological non-responders show low SKAP1 concentration and DNA hypermethylation in the SKAP1 promotor region: Low Skap1 in HIV Immunological Non-Responders.

    AIDS (London, England)

    Authors: Wilhelm Ajw Vos, Suzanne De Ruijten, Xun Jiang, Nienke van Unen, Willem van Snippenberg, Albert L Groenendijk, Marc J T Blaauw, Louise Evan Eekeren, Nadira Vadaq, Hanneke Maas, Malin Östman, Maartje C P Cleophas, Kees Brinkman, Jan van Lunzen, Willem L Blok, Janneke E Stalenhoef, Yang Li, Mihai G Netea, Linos Vandekerckhove, Jéssica C Dos Santos, Vasiliki Matzaraki, Cheng-Jian Xu, Andre Jam van der Ven

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  • Interferon-related inflammaging links epigenetic age acceleration to multimorbidity.

    Cell genomics

    Authors: Zhaoli Liu, Athanasios Ziogas, Yihan Zhang, Manoj Kumar Gupta, Konstantin Föhse, Esther Taks, Elisabeth Dulfer, Andrei Sarlea, Lorenzo Ventriglia, Büsra Geckin, Mohamad Ballan, Nienke van Unen, Leonie Helder, Stephanie Trittel, Peggy Riese, Simone Moorlag, Charlotte de Bree, Valerie Koeken, Vera Mourits, Martin Jaeger, Frank Pessler, Carlos A Guzmán, Leo A B Joosten, Yang Li, Cheng-Jian Xu, Mihai G Netea

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  • Trained immunity induction by vaccines adjuvants.

    Current opinion in virology

    Authors: Ghazal Sodaifi, Mihai G Netea

    View this publication