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Prof. Dr. Oliver Brüstle

Member

Institute of Reconstructive Neurobiology

Venusberg-Campus 1, 53127 Bonn

brustle@uni-bonn.de

+49 228 6885500

Our lab is focusing on the use of human pluripotent stem cells for disease modeling and neuroregeneration, for which we offer a broad scope of experimental systems ranging from targeted differentiation of human ES and iPS cells into diverse neural subtypes as well as microglia via direct cell fate conversion to brain organoid models and neurotransplantation. 

Prof. Dr. Oliver Brüstle

Recent publications

  • Protracted Fate Acquisition and Epigenetic De-Aging During Induced Neural Stem Cell Conversion of Human Blood Cells.

    Aging cell

    Authors: Lea Jessica Berg, Julia Franzen, Andreas Buness, Rachel Konang, Chao Sheng, Michael Peitz, Andreas Till, Wolfgang Wagner, Oliver Brüstle

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  • Mapping human microglial morphological diversity via handcrafted and deep learning-derived image features.

    iScience

    Authors: Kayhan Alvandipour, Amélie Weiss, Mona Mathews, Brenda Besemer, Michaela Segschneider, Zahra Hanifehlou, Christian Felski, Michael Peitz, Arnaud Ogier, Peter Sommer, Oliver Brüstle, Johannes H Wilbertz

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  • Induced neural stem cells in neuroregeneration: Progress and clinical prospects.

    Neural regeneration research

    Authors: Hideaki Matsumura, Oliver Brüstle

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