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Prof. Dr. Oliver Brüstle

Member

Institute of Reconstructive Neurobiology

Venusberg-Campus 1, 53127 Bonn

brustle@uni-bonn.de

+49 228 6885500

Our lab is focusing on the use of human pluripotent stem cells for disease modeling and neuroregeneration, for which we offer a broad scope of experimental systems ranging from targeted differentiation of human ES and iPS cells into diverse neural subtypes as well as microglia via direct cell fate conversion to brain organoid models and neurotransplantation. 

Prof. Dr. Oliver Brüstle

Recent publications

  • Mapping human microglial morphological diversity via handcrafted and deep learning-derived image features.

    iScience

    Authors: Kayhan Alvandipour, Amélie Weiss, Mona Mathews, Brenda Besemer, Michaela Segschneider, Zahra Hanifehlou, Christian Felski, Michael Peitz, Arnaud Ogier, Peter Sommer, Oliver Brüstle, Johannes H Wilbertz

  • Induced neural stem cells in neuroregeneration: Progress and clinical prospects.

    Neural regeneration research

    Authors: Hideaki Matsumura, Oliver Brüstle

  • Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer's disease.

    Cell reports methods

    Authors: Matthias Hebisch, Viola Kamin, Giovanna Cenini, Antonia Piazzesi, Fabio Bertan, Beatrice Weykopf, Julia Schlee, Senthilvelrajan Kaniyappan, Kevin J Washicosky, Doo Yeon Kim, Daniele Bano, Michael Peitz, Oliver Brüstle

All publications by Prof. Dr. Oliver Brüstle