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Prof. Dr. Oliver Brüstle

Member

Institute of Reconstructive Neurobiology

Venusberg-Campus 1, 53127 Bonn

brustle@uni-bonn.de

+49 228 6885500

Our lab is focusing on the use of human pluripotent stem cells for disease modeling and neuroregeneration, for which we offer a broad scope of experimental systems ranging from targeted differentiation of human ES and iPS cells into diverse neural subtypes as well as microglia via direct cell fate conversion to brain organoid models and neurotransplantation. 

Prof. Dr. Oliver Brüstle

Recent publications

  • Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer's disease.

    Cell reports methods

    Authors: Matthias Hebisch, Viola Kamin, Giovanna Cenini, Antonia Piazzesi, Fabio Bertan, Beatrice Weykopf, Julia Schlee, Senthilvelrajan Kaniyappan, Kevin J Washicosky, Doo Yeon Kim, Daniele Bano, Michael Peitz, Oliver Brüstle

  • Effects of lipopolysaccharide on energy metabolism and immune cell activation in different microglia model systems.

    Brain, behavior, and immunity

    Authors: Susanne Michels, Johanna Eichberg, Fahd Alhamdan, Micha Engeser, Rafael Leite Dantas, Felix Sr Picard, Mona Mathews-Ajendra, Oliver Brüstle, Martin K-H Schäfer, Judith Alferink, Holger Garn, Markus Wöhr, Carsten Culmsee

  • Modelling inflammation-induced peripheral sensitization in a dish-more complex than expected?

    Pain

    Authors: Yuening Li, Amy Lock, Laura Fedele, Irene Zebochin, Alba Sabate, Matthew Siddle, Silvia Cainarca, Pascal Röderer, Katharina Montag, Paola Tarroni, Oliver Brüstle, Tanya Shaw, Leonie Taams, Franziska Denk

All publications by Prof. Dr. Oliver Brüstle