Immune monitoring of SARS-CoV-2-specific T cell and B cell responses in patients with multiple sclerosis treated with ocrelizumab.
Frontiers in immunology
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Medical Faculty, University of Bonn University Hospital of Bonn Venusberg - Campus 1 53127 Bonn
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS) and the most frequent neurological disease in young adults, leading to irreversible clinical deficits and premature retirement. On the one hand, my group focuses on the contribution of B cells and autoantibodies to the immunopathology of MS. Next to understanding the mechanisms of B cell-driven disease, we aim to develop novel therapeutic options and biomarkers for patients with MS. On the other hand, we are concerned with developing strategies to promote neuroregeneration and remyelination in the CNS. In addition, my group is concerned with studying the involvement of the enteric nervous system (ENS), dietary factors and food antigens in MS.
Frontiers in immunology
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View this publicationFrontiers in immunology
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