Myeloperoxidase and anti-MPO IgG synergistically enhance TLR9-mediated immune activation in ANCA-associated vasculitis.
Cell reports
View this publicationMember
Venusberg-Campus 1, 53127 Bonn
Valentin Schäfer's research groups focuses on advanced imaging and immunological mechanisms in vasculitides, particularly large-vessel vasculitis and ANCA-associated vasculitides. His work investigates resistance mechanisms to immunosuppressive therapies in rheumatoid and psoriatic arthritis through synovial biopsies. Additionally, he examines Vascular Adhesion Protein-1 (VAP-1) as a therapeutic target and molecular imaging marker, employing [68Ga]Ga-DOTA-Siglec-9-PET/CT in rheumatologic diseases. By leveraging innovative technologies such as 3D printing, artificial intelligence, and advanced ultrasound, his research bridges fundamental science, clinical practice, and education to advance diagnostics, patient care, and medical training.
Cell reports
View this publicationRMD open
View this publicationRMD open
View this publication