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Prof. Dr. Valentin Sebastian Schäfer

Member

Valentin Schäfer's research groups focuses on advanced imaging and immunological mechanisms in vasculitides, particularly large-vessel vasculitis and ANCA-associated vasculitides. His work investigates resistance mechanisms to immunosuppressive therapies in rheumatoid and psoriatic arthritis through synovial biopsies. Additionally, he examines Vascular Adhesion Protein-1 (VAP-1) as a therapeutic target and molecular imaging marker, employing [68Ga]Ga-DOTA-Siglec-9-PET/CT in rheumatologic diseases. By leveraging innovative technologies such as 3D printing, artificial intelligence, and advanced ultrasound, his research bridges fundamental science, clinical practice, and education to advance diagnostics, patient care, and medical training.

Prof. Dr. Valentin Schäfer

Recent publications

  • Myeloperoxidase and anti-MPO IgG synergistically enhance TLR9-mediated immune activation in ANCA-associated vasculitis.

    Cell reports

    Authors: Calvin Krollmann, Maria-Lourdes Saenz, Ruth-Miriam Koerber, Kevin Cieslak, Angela Rösen-Wolff, Peter Brossart, Valentin S Schäfer, Natalio Garbi, Abraham Rutgers, Peter Heeringa, Lino L Teichmann

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  • Comparison of four clinical risk prediction models for the diagnosis of giant cell arteritis: results from the ongoing PREDICT-GCA study.

    RMD open

    Authors: Lukas-Casper Thielmann, Christian Lottspeich, Lilly Juliane Undine Reik, Tobias Wirthmiller, Andreas Nützel, Holger Schneider, Anja Löw, Teresa Henke, Ilaria Prearo, Marc J Mackert, Siegfried Priglinger, Heiko Schulz, Christoph Walz, Elisabeth Haas-Lützenberger, Christina Gebhardt, Claus-Jürgen Bauer, Valentin S Schäfer, Hendrik Schulze-Koops, Michael Czihal

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  • Comparative evaluation of disease activity measures for adult-onset Still's disease: a multicentre, retrospective, cohort study.

    RMD open

    Authors: Stefan Vordenbäumen, Tim Filla, Rhea Friedrich, Norbert Blank, Diana Ernst, Jörg Henes, Gernot Keyßer, Philipp Klemm, Martin Krusche, Anna Meinecke, Jürgen Rech, Nils Schulz, Simon Michael Petzinna, Anne Pankow, Valentin S Schäfer, Alexander Pfeil, Sebastian Klapa, Georg Pongratz, Eugen Feist, Anna Kernder

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