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Jun.-Prof. Tim Rollenske

Member

Institute of Molecular Medicine and Experimental Immunology

Medical Faculty, University of Bonn, University Hospital of Bonn, Sigmund-Freud-Strasse 25 53105 Bonn

tim.rollenske@uni-bonn.de

+49 228 28751012

Website

Our mucosal body surfaces inhabit a myriad of microbes, our microbiota. Antibodies are important to control our microbiota and to protect from pathogens. The Mucosal Immunology group studies the B cell response to microbiota and infection at mucosal surfaces. We use human samples and gnotobiotic mouse models paired with single cell B cell receptor repertoire analysis and monoclonal antibody testing to functionally define how the humoral immune system contributes to a mutualistic host-microbe relationship.

Recent publications

  • Clonal persistence dominates homeostatic intestinal IgA responses.

    Immunity

    Authors: Britta Simons, Hieu Trong Nguyen, Atscharah Panyot, Fabian Tobias Hager, Johanna Kabbert, Asmae Laouina, Jonathan Schreiber, Lydia Kopplin, Tim Rollenske, Thomas Clavel, Oliver Pabst

    View this publication
  • Efficient Expression and Purification of Recombinant Mouse Dimeric IgA.

    European journal of immunology

    Authors: Antonia Geisse, Tao Zhang, Jonathan Schreiber, Kristina Markova, Sophie Burkhalter, Hedda Wardemann, Andrew J Macpherson, Tim Rollenske

    View this publication
  • Mucosal stargazing: IgA keeps astrovirus in check.

    Cell host & microbe

    Authors: Tim Rollenske

    View this publication