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Jun.-Prof. Tim Rollenske

Member

Institute of Molecular Medicine and Experimental Immunology

Medical Faculty, University of Bonn, University Hospital of Bonn, Sigmund-Freud-Strasse 25 53105 Bonn

tim.rollenske@uni-bonn.de

+49 228 28751012

Website

Our mucosal body surfaces inhabit a myriad of microbes, our microbiota. Antibodies are important to control our microbiota and to protect from pathogens. The Mucosal Immunology group studies the B cell response to microbiota and infection at mucosal surfaces. We use human samples and gnotobiotic mouse models paired with single cell B cell receptor repertoire analysis and monoclonal antibody testing to functionally define how the humoral immune system contributes to a mutualistic host-microbe relationship.

Tim_Rollenske

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Recent publications

  • AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins.

    Nature communications

    Authors: Bianca Broske, Benjamin A McEnroe, Sophie C Frechen, Tim N Kempchen, Caroline I Fandrey, Elisabeth Tan, Dominic Ferber, Michelle C R Yong, Marie Kleinert, Julia M Messmer, Peter Konopka, Alexander Hoch, Katja Blumenstock, Jan M P Tödtmann, Johannes Oldenburg, Heiko Rühl, Alexander Semaan, Marieta I Toma, Kristina Markova, Sebastian Kobold, Tim Rollenske, Matthias Geyer, Stephan Menzel, Tobias Bald, Jonathan L Schmid-Burgk, Gregor Hagelueken, Michael Hölzel

  • Distinct postnatal trajectories of mouse dendritic epidermal T cells and Langerhans cells independent of microbiota.

    Science advances

    Authors: David Obwegs, Alexander Oschwald, Lara M Koetter, Cylia Crisand, Sidney Doerr, Kerstin Bruder, Solveig Runge, Nisreen Ghanem, Vidmante Fuchs, Marleen Eckert, Christian Koengeter, Anna-Maria Schaffer, Lukas Amann, Sophia Papaioannou, Tim Rollenske, Julia Kolter, Daniel Erny, Marco Prinz, Susana Minguet, Wolfgang W Schamel, Philipp Henneke, Stephan P Rosshart, Katrin Kierdorf, Sagar

  • Non-selective β-blockers reduce bacterial translocation by restoring gut barrier function during experimental cirrhosis.

    Journal of hepatology

    Authors: Elisa Castillo, Marco Felber, Lorena Paule, Oriol Juanola, Lorena Wyss, Tim Wolfisberg, Sandro Christensen, Leticia Muñoz, Alejandro Miranda, Manuel Ponce-Alonso, Olaya de Dios, Rosa Del Campo, Oscar Pastor, Miguel A Ortega, Melchor Álvarez-Mon, Tim Rollenske, Sheida Moghadamrad, Andrea de Gottardi, Stephanie Ganal-Vonarburg, Bahtiyar Yilmaz, Val F Lanza, Eric Felli, Philipp Kellmann, Rubén Francés, Agustín Albillos, Reiner Wiest

All publications by Jun.-Prof. Tim Rollenske