Expression Cloning of Antibodies from Single Human B Cells.
Methods in molecular biology (Clifton, N.J.)
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Medical Faculty, University of Bonn, University Hospital of Bonn, Sigmund-Freud-Strasse 25 53105 Bonn
Our mucosal body surfaces inhabit a myriad of microbes, our microbiota. Antibodies are important to control our microbiota and to protect from pathogens. The Mucosal Immunology group studies the B cell response to microbiota and infection at mucosal surfaces. We use human samples and gnotobiotic mouse models paired with single cell B cell receptor repertoire analysis and monoclonal antibody testing to functionally define how the humoral immune system contributes to a mutualistic host-microbe relationship.
Methods in molecular biology (Clifton, N.J.)
View this publication