Skip to main content
News Icon

News categories: Publication

Artificial Intelligence Tracks down Leukemia

Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia (AML) - with high reliability. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn have now shown this in a proof-of-concept study. Their approach is based on the analysis of the gene activity of cells found in the blood. Used in practice, this approach could support conventional diagnostics and possibly accelerate the beginning of therapy. The research results have been published in the journal “iScience”.

Cluster member and speaker of the Cluster of Excellence Prof. Joachim Schultze led the study in Bonn.

Publication

Scalable prediction of acute myeloid leukemia using high-dimensional machine learning and blood transcriptomics; Stefanie Warnat-Herresthal, Konstantinos Perrakis et al., iScience (2019),
DOI: 10.1016/j.isci.2019.100780

Related news

Kato research group

News categories: Publication

Ominous false alarm in the kidney

Bonn researchers have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction. In cooperation with Nanyang Technological University Singapore and the University Hospital Würzburg, among others, the study provides an explanation for how a point mutation in the immune receptor RIG-I transforms the body's defense system into a self-destructive force and causes severe organ-specific autoimmune diseases. The results have now been published in the journal Science Immunology.
View entry
Collage Boztug Kalinichenko Huemer 1200px

News categories: Publication

How immune cells deliver their deadly cargo

Precision is crucial for immune cells: natural killer (NK) cells and T cells eliminate infected or transformed cells by releasing targeted, highly toxic particles. A new study from the CeMM (Research Center for Molecular Medicine of the Austrian Academy of Sciences), the St. Anna Children’s Cancer Research Institute, the Medical University of Vienna, the Medical University of Graz, the University Hospital Bonn (UKB) and the University of Bonn offers deeper insight into how these so-called cytotoxic granules are released.
View entry
Kurts_PM_161025

News categories: Publication

Less can be more: Low-dose steroids could effectively treat severe kidney inflammation

Study by researchers in Bonn and Hamburg shows that lower doses of cortisone may be sufficient for aggressive kidney inflammation.
View entry

Back to the news overview