Skip to main content
News Bradke 08.2019
(Dorsal root ganglia) neuron under the microscope.
© Barbara Schaffran / DZNE

News categories: Publication

Cluster Member Bradke publishes in Neuron

Cluster member Prof. Bradke, who works at the German Center for Neurodegenerative Diseases (DZNE) and his group have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal "Neuron".

It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs normally after they have found their target cells and established synapses. However, recent findings show that old nerve cells have the potential to regrow and to repair damage similar to young neurons. The underlying mechanisms for this rejuvenation have now been uncovered in laboratory studies led by the team of Professor Frank Bradke at the DZNE's Bonn site together with scientists of the University of Bonn.


Publication

ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS. Andrea Tedeschi, Sebastian Dupraz, Michele Curcio, Claudia J. Laskowski, Barbara Schaffran et al. Neuron (2019). DOI: 10.1016/j.neuron.2019.07.007

Related news

Collage Boztug Kalinichenko Huemer 1200px

News categories: Publication

How immune cells deliver their deadly cargo

Precision is crucial for immune cells: natural killer (NK) cells and T cells eliminate infected or transformed cells by releasing targeted, highly toxic particles. A new study from the CeMM (Research Center for Molecular Medicine of the Austrian Academy of Sciences), the St. Anna Children’s Cancer Research Institute, the Medical University of Vienna, the Medical University of Graz, the University Hospital Bonn (UKB) and the University of Bonn offers deeper insight into how these so-called cytotoxic granules are released.
View entry
Kurts_PM_161025

News categories: Publication

Less can be more: Low-dose steroids could effectively treat severe kidney inflammation

Study by researchers in Bonn and Hamburg shows that lower doses of cortisone may be sufficient for aggressive kidney inflammation.
View entry
News_Lukacs-Kornek

News categories: Publication

Obesity causes lungs to age prematurely

What effects does severe obesity have on the lungs? A research team led by Prof. Dr. Veronika Lukacs-Kornek from the ‘ImmunoSensation2’ Cluster of Excellence at the University of Bonn and the Institute for Molecular Medicine and Experimental Immunology (IMMEI) at the University Hospital Bonn (UKB) investigated this question. The results suggest that obesity causes the lungs to age faster. The findings have been published in the journal ‘Cell Reports’.
View entry

Back to the news overview