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News Beck 10.2019
An interneuron (bright, with long appendages) from the hippocampus of the rat. The finely branched axon (top left cloud) surrounds the cell bodies of pyramidal cells and can inhibit these effectively.
© Leonie Pothmann/Uni Bonn

Publication

Epilepsy: Function of "brake cells" disrupted

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn with members of the cluster of excellence ImmunoSensation2, in which researchers from Lisbon were also involved, points in this direction. The results are published in the renowned "Journal of Neuroscience".

Publication

Leonie Pothmann, Christian Klos, Oliver Braganza, Sarah Schmidt, Oihane Horno, Raoul-Martin Memmesheimer and Heinz Beck: Altered dynamics of canonical feed-back inhibition predicts increased burst transmission in chronic epilepsy; The Journal Of Neuroscience; https://doi.org/10.1523/JNEUROSCI.2594-18.2019

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Publication

Weight-Loss Pill Instead of Injection: Finally, an Easy Way to Lose Weight?

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Prof. Matthias Geyer, - together with Prof. Robert P. Fisher from New York, provides an overview of the current state of research on the transcriptional regulation of cyclin-dependent kinases (CDKs) and the prospects for cancer treatment.

Publication

A Ray of Hope in the Fight Against Cancer

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(from left) Julia Nicke and Dr. Mona Malek Mohammadi have identified a previously unknown signaling pathway in the immune system that helps newborn heart cells survive and regenerate after injury.

Publication

Central Hub for Heart Repair Discovered Bonn study: Heart muscle interaction enables cardiac regeneration in the neonatal heart

—Researchers at the University Hospital of Bonn (UKB) and the University of Bonn have identified a previously unknown signaling pathway in the immune system that helps newborn heart cells survive and regenerate after injury. The findings could open new avenues for future therapies aimed at repairing damaged adult hearts after heart attacks or chronic cardiovascular disease. The study has now been published in the journal Cell Communication and Signaling (Springer Nature).
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