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News Preiffer 06.2020
Prof. Dr. Alexander Pfeifer (left) and Dr. Thorsten Gnad (right) from the Institute of Pharmacology and Toxicology at the University Hospital Bonn.
© Katharina Wislsperger/UKBonn

Publication

Receptor makes mice strong and slim

Study by the University of Bonn identifies molecule that regulates two side effects of aging

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn from the Cluster of Excellence ImmunoSensation have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in humans. The study, which also involved researchers from Spain, Finland, Belgium, Denmark and the USA, has now been published in the renowned journal "Cell Metabolism".

Publication

Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer: Adenosine/A2B receptor signaling ameliorates the effects of ageing and counteracts obesity. Cell Metabolism, DOI: https://doi.org/10.1016/j.cmet.2020.06.006

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Publication

Researchers Transform Old Blood Cells into Young Brain Cells

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Publication

Aspirin Rarely Used for Colorectal Cancer Prevention

—According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer – even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice. The results of the LYNX study have now been published as a letter in the journal The Lancet Gastroenterology & Hepatology.
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Publication

Smartphones as Retinal Cameras: New Opportunities for Global Eye Care

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