Skip to main content
Graphical abstract for Tsukamoto et al., Targeting cap1 RNA methyltransferases as an antiviral strategy, Cell Chemical Biology (2023)

News categories: Publication

Review on new antiviral strategy now online

The review publication of Yuta Tsukamoto et al. is now available in the current issue of Cell Chemical Biology. Based on his latest Science paper, Yuta Tsukamoto now highlights the importance and potential of “Targeting cap1 RNA methyltransferases as an antiviral strategy”. He and his co-authors outline the game-changing options in the treatment of viral infections.


Publication

Tsukamoto Y, Igarashi M, Kato H.
Targeting cap1 RNA methyltransferases as an antiviral strategy.
Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00426-9.
doi: 10.1016/j.chembiol.2023.11.011.
Epub ahead of print. PMID: 38091983.

Related news

Nora Möhn

News categories: Publication

New Findings on Immunotherapy for a Rare Brain Infection

Progressive multifocal leukoencephalopathy (PML) is a rare but very serious brain disease. It is caused by the reactivation of the widespread JC virus when the immune system is severely weakened. There is currently no targeted antiviral therapy available, which is why new treatment approaches are urgently needed. In recent years, so-called immune checkpoint inhibitors have been increasingly used; these “unlock” the immune system and reactivate the body’s own immune cells. The results were recently published in the journal JAMA Neurology.
View entry
Die künstlerische Abbildung zeigt Seeigel der Art Arbacia punctulata, die Spermien (weiße Wolke) und Eier (orangefarbene Wolke) ins Wasser abgeben. Von den Eiern freigesetzte Pheromone steuern die Synchronität des Laichens.

News categories: Publication

What Makes Sea Urchin and Salmon Sperm Swim

A recent study by the Max Planck Institute for Multidisciplinary Sciences and the University of Bonn shows that pH plays a crucial role in sperm motility in sea urchins and salmon. A rise in pH activates the enzyme soluble adenylyl cyclase (sAC), which produces the messenger molecule cAMP and thereby regulates sperm movement. This mechanism may be widespread in many marine invertebrates and fish. The findings have now been published in the Journal Proceedings of the National Academy of Sciences.
View entry
3 Wissenschaftler

News categories: Publication

Immune cells remember their location

A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually. To accomplish this, Researchers at the University Hospital Bonn (UKB) and the University of Bonn use the transcriptome, i.e., the entirety of all messenger RNA transcripts produced by genes within a cell at a given time. The work has now been published in the journal Advanced Science and introduces the new MERLIN algorithm.
View entry

Back to the news overview