Skip to main content
Graphical abstract for Tsukamoto et al., Targeting cap1 RNA methyltransferases as an antiviral strategy, Cell Chemical Biology (2023)

News categories: Publication

Review on new antiviral strategy now online

The review publication of Yuta Tsukamoto et al. is now available in the current issue of Cell Chemical Biology. Based on his latest Science paper, Yuta Tsukamoto now highlights the importance and potential of “Targeting cap1 RNA methyltransferases as an antiviral strategy”. He and his co-authors outline the game-changing options in the treatment of viral infections.


Publication

Tsukamoto Y, Igarashi M, Kato H.
Targeting cap1 RNA methyltransferases as an antiviral strategy.
Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00426-9.
doi: 10.1016/j.chembiol.2023.11.011.
Epub ahead of print. PMID: 38091983.

Related news

Kato research group

News categories: Publication

Ominous false alarm in the kidney

Bonn researchers have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction. In cooperation with Nanyang Technological University Singapore and the University Hospital Würzburg, among others, the study provides an explanation for how a point mutation in the immune receptor RIG-I transforms the body's defense system into a self-destructive force and causes severe organ-specific autoimmune diseases. The results have now been published in the journal Science Immunology.
View entry
News Icon

News categories: Publication

Unique immune signatures to distinguish MOGAD from MS

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune condition in which the body’s immune system mistakenly attacks the protective myelin sheath of nerve fibers in the central nervous system. Although MOGAD induces symptoms similar to multiple sclerosis (MS), its underlying biology appears to be fundamentally different. Understanding these distinctions is crucial for developing effective, disease-specific treatments. A new international study now sheds light on these immune differences.
View entry
Collage Boztug Kalinichenko Huemer 1200px

News categories: Publication

How immune cells deliver their deadly cargo

Precision is crucial for immune cells: natural killer (NK) cells and T cells eliminate infected or transformed cells by releasing targeted, highly toxic particles. A new study from the CeMM (Research Center for Molecular Medicine of the Austrian Academy of Sciences), the St. Anna Children’s Cancer Research Institute, the Medical University of Vienna, the Medical University of Graz, the University Hospital Bonn (UKB) and the University of Bonn offers deeper insight into how these so-called cytotoxic granules are released.
View entry

Back to the news overview