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[Physiological reactions in the interface between cementless implants and bone].

Orthopadie (Heidelberg, Germany)

Authors: Frank Sebastian Fröschen, Dieter Christian Wirtz, Frank Alexander Schildberg

BACKGROUND: Surgical treatment of patients with osteoarthritis of the hip and persisting symptoms under conservative therapy has become increasingly important against the background of an aging population.

OBJECTIVES: What are the physiological reactions in the interface between cementless implants and bone?

METHODS: The literature is reviewed, expert opinions and animal models are analyzed and discussed.

RESULTS: Surface coating of implants with hydroxyapatite or titanium can have positive effects on osteointegration. Additional local application of mediators might be beneficial for osteointegration in the future.

CONCLUSION: Early peri-implant bone healing directly after implantation and late remodeling of the bone-implant interface are essential for secondary implant stability.

© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

PMID: 36749380

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