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  • Epigenetic remodeling via HDAC6 inhibition amplifies anti-tumoral immune responses in myeloid leukemia cells.

    Cell death & disease

    Authors: Julian Schliehe-Diecks, Jia-Wey Tu, Pawel Stachura, Katerina Schaal, Marie Kemkes, Eleni Vasileiou, Nadine Rüchel, Danielle Brandes, Melina Vogt, Thomas Lenz, Adarsh Nair, Stefanie Scheu, Pilar M Dominguez, Agata Pastorczak, Karin Nebral, Kai Stühler, Ute Fischer, Aleksandra A Pandyra, Arndt Borkhardt, Sanil Bhatia

  • Serum-free differentiation platform for the generation of B lymphocytes and natural killer cells from human CD34+ cord blood progenitors.

    Scientific reports

    Authors: Rigveda Bhave, Carla-Johanna Kath, Nadine Rüchel, Eleni Vasileiou, Vera H Jepsen, Katharina Raba, Aleksandra A Pandyra, Ute Fischer, Gesine Kogler

  • Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL

    Cell Death and Disease

    Authors: Stachura P, Lu Z, Kronberg RM, Xu HC, Liu W, Tu JW, Schaal K, Kameri E, Picard D, von Karstedt S, Fischer U, Bhatia S, Lang PA, Borkhardt A, Pandyra AA

  • A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers.

    Frontiers in public health

    Authors: Ersen Kameri, Vera Helena Jepsen, Pawel Stachura, Nadine Rüchel, Rigveda Bhave, Leticia Benitez, Fatima Crispi, Eduard Gratacos, Nico Dragano, Stefan Janssen, Arndt Borkhardt, Aleksandra Pandyra, Gesine Kögler, Ute Fischer

  • Deciphering the Therapeutic Potential of Novel Pentyloxyamide-Based Class I, IIb HDAC Inhibitors against Therapy-Resistant Leukemia.

    Journal of medicinal chemistry

    Authors: Fabian Fischer, Julian Schliehe-Diecks, Jia-Wey Tu, Tanja Gangnus, Yu Lin Ho, Mara Hebeis, Leandro A Alves Avelar, Katerina Scharov, Titus Watrin, Marie Kemkes, Pawel Stachura, Katharina Daugs, Lukas Biermann, Josefa Kremeyer, Nadine Horstick, Ingrid Span, Aleksandra A Pandyra, Arndt Borkhardt, Holger Gohlke, Matthias U Kassack, Bjoern B Burckhardt, Sanil Bhatia, Thomas Kurz

  • A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS involvement of BCP-ALL.

    Blood advances

    Authors: Philip Gebing, Stefanos Loizou, Sebastian Hänsch, Julian Schliehe-Diecks, Lea Spory, Pawel Stachura, Vera H Jepsen, Melina Vogt, Aleksandra A Pandyra, Herui Wang, Zhengping Zhuang, Johannes Zimmermann, Martin Schrappe, Gunnar Cario, Ameera Alsadeq, Denis M Schewe, Arndt Borkhardt, Lennart Lenk, Ute Fischer, Sanil Bhatia

  • High-Affinity-Mediated Viral Entry Triggers Innate Affinity Escape Resulting in Type I IFN Resistance and Impaired T Cell Immunity.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Haifeng C Xu, Piyush Pandey, Harry Ward, Michal Gorzkiewicz, Džiuljeta Abromavičiūtė, Constanze Tinz, Lisa Müller, Caroline Meyer, Aleksandra A Pandyra, Aslihan Yavas, Arndt Borkhardt, Irene Esposito, Karl S Lang, Philipp A Lang