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Dr. Anna C. Aschenbrenner

Member, Steering-Committee Member

Systems Medicine - German Center for Neurodegenerative Diseases (DZNE)

DZNE Venusberg-Campus 1 53127 Bonn

anna.aschenbrenner@dzne.de

+49 228 43302690

Website

Dr. Aschenbrenner earned her PhD in developmental biology after studying Molecular Biomedicine at the University of Bonn and the University of Pennsylvania. She then strategically transitioned to systems immunology, leveraging her extensive expertise in genetic models, molecular biology, signalling and physiology to understand immune cells in health and disease. Her research places particular emphasis on integrating advanced genomics technologies with state-of-the-art bioinformatic approaches. As a group leader at the DZNE, she drives projects at the intersection of human immunology, translational clinical research, and data science, fostering cross-disciplinary collaborations. Her work focuses on patient stratification, disease endotyping, biomarker discovery, and the prediction of therapy outcomes, employing national and European data protection-compliant analytical frameworks and assisted learning methods.

Anna Aschenbrenner

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Recent publications

  • Unveiling the power of high-dimensional cytometry data with cyCONDOR.

    Nature communications

    Authors: Charlotte Kröger, Sophie Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat-Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, Frank Jessen, Simone Puccio, Anna C Aschenbrenner, Joachim L Schultze, Tal Pecht, Marc D Beyer, Lorenzo Bonaguro

  • Top publication

    The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.

    Cell

    Authors: Rainer Knoll, Elisa T Helbig, Kilian Dahm, Olufemi Bolaji, Frederik Hamm, Oliver Dietrich, Martina van Uelft, Sophie Müller, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Lev Petrov, Benjamin Krämer, Michael Kraut, Paula Stubbemann, Charlotte Thibeault, Sophia Brumhard, Heidi Theis, Gudrun Hack, Elena De Domenico, Jacob Nattermann, Matthias Becker, Marc D Beyer, David Hillus, Philipp Georg, Constantin Loers, Janina Tiedemann, Pinkus Tober-Lau, Lena Lippert, Belén Millet Pascual-Leone, Frank Tacke, Gernot Rohde, Norbert Suttorp, Martin Witzenrath, Antoine-Emmanuel Saliba, Thomas Ulas, Julia K Polansky, Birgit Sawitzki, Leif E Sander, Joachim L Schultze, Anna C Aschenbrenner, Florian Kurth

  • The pathophysiology of sepsis and precision-medicine-based immunotherapy.

    Nature immunology

    Authors: Evangelos J Giamarellos-Bourboulis, Anna C Aschenbrenner, Michael Bauer, Christoph Bock, Thierry Calandra, Irit Gat-Viks, Evdoxia Kyriazopoulou, Mihaela Lupse, Guillaume Monneret, Peter Pickkers, Joachim L Schultze, Tom van der Poll, Frank L van de Veerdonk, Alexander P J Vlaar, Sebastian Weis, W Joost Wiersinga, Mihai G Netea

All publications by Dr. Anna C. Aschenbrenner