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Dr. Niklas Klümper

Member

Department of Urology and Institute of Experimental Oncology

niklas.kluemper@ukbonn.de

+49 228 28751394

Website

PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    Authors: Niklas Klümper, Ngoc Khanh Tran, Stefanie Zschäbitz, Oliver Hahn, Thomas Büttner, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Constantin Schwab, Dora Nagy, Marieta Toma, Glen Kristiansen, Hendrik Heers, Philipp Ivanyi, Günter Niegisch, Camilla Marisa Grunewald, Christopher Darr, Arian Farid, Katrin Schlack, Mahmoud Abbas, Can Aydogdu, Jozefina Casuscelli, Theresa Mokry, Michael Mayr, Dora Niedersüß-Beke, Steffen Rausch, Dimo Dietrich, Jonas Saal, Jörg Ellinger, Manuel Ritter, Abdullah Alajati, Christoph Kuppe, Joshua Meeks, Francisco E Vera Badillo, J Alberto Nakauma-González, Joost Boormans, Kerstin Junker, Arndt Hartmann, Viktor Grünwald, Michael Hölzel, Markus Eckstein

  • Biomarkers of Response to Anti-NECTIN4 Antibody-Drug Conjugate Enfortumab Vedotin in Urothelial Cancer.

    European urology focus

    Authors: Niklas Klümper, Markus Eckstein

  • Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.

    American journal of respiratory and critical care medicine

    Authors: Nina Wyss, Fiamma Berner, Vincent Walter, Ann-Kristin Jochum, Mette T Purde, Marie-Therese Abdou, Tobias Sinnberg, Kathrin Hofmeister, Oltin T Pop, Omar Hasan Ali, Jens Bauer, Hung-Wei Cheng, Mechthild Lütge, Niklas Klümper, Stefan Diem, Zeynep Kosaloglu-Yalcin, Yizheng Zhang, Laura Sellmer, Boris Macek, Julia Karbach, David König, Heinz Läubli, Lars Zender, Britta S Meyer, Christoph Driessen, Christian M Schürch, Wolfram Jochum, Teresa Amaral, Lucie Heinzerling, Antonio Cozzio, Ahmed N Hegazy, Tino Schneider, Martin H Brutsche, Alessandro Sette, Tobias L Lenz, Juliane Walz, Hans-Georg Rammensee, Martin Früh, Elke Jäger, Burkhard Becher, Amanda Tufman, Nicolas Nuñez, Markus Joerger, Lukas Flatz

All publications by Dr. Niklas Klümper