Skip to main content

Dr. Niklas Klümper

Member

Department of Urology and Institute of Experimental Oncology

niklas.kluemper@ukbonn.de

+49 228 28751394

Website

PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • TROP-2 overexpression in papillary renal cell carcinoma supports its potential as a therapeutic target for antibody-drug-conjugate therapy.

    World journal of urology

    Authors: Carolina Kessler, Melanie von Brandenstein, Niklas Klümper, Philipp Krausewitz, Enno Storz, Constantin Rieger, Laurenz Sperber, Pia Paffenholz, Yuri Tolkach, Ralph Wirtz, Markus Eckstein, Axel Heidenreich, Richard Weiten

  • NaCl and urea modulate CD8+ T cell survival, renal accumulation and response to BK virus.

    JCI insight

    Authors: Peyman Falahat, Adrian Goldspink, Lucia Oehler, Jessica Schmitz, Julia Miranda, Islem Gammoudi, Jan Hinrich Bräsen, Niklas Klümper, Olena Babyak, Christian Kurts, Herrmann Haller, Marieta Toma, Sibylle von Vietinghoff

  • AI allows pre-screening of FGFR3 mutational status using routine histology slides of muscle-invasive bladder cancer.

    Nature communications

    Authors: Pierre-Antoine Bannier, Charlie Saillard, Philipp Mann, Maxime Touzot, Charles Maussion, Christian Matek, Niklas Klümper, Johannes Breyer, Ralph Wirtz, Danijel Sikic, Bernd Schmitz-Dräger, Bernd Wullich, Arndt Hartmann, Sebastian Försch, Markus Eckstein

All publications by Dr. Niklas Klümper