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Dr. Niklas Klümper

Member

Department of Urology and Institute of Experimental Oncology

niklas.kluemper@ukbonn.de

+49 228 28751394

Website

PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • FGFR3 Testing in Urothelial Carcinoma: An Expert Commentary on Best Practices From Patient Identification to Result Reporting.

    European urology oncology

    Authors: Eva M Compérat, Arndt Hartmann, Yves Allory, Beatriz Bellosillo, Rui Pedro Caetano Moreira Oliveira, Caterina Chiappetta, Farah Hodeib, Michael Hubank, Niklas Klümper, Yohann Loriot, Frédérique Penault-Llorca, Astrid Rijken, Ernst-Jan M Speel, Bernadett Szabados, Isabelle Vanden Bempt, Geert J L H Van Leenders, Mariavittoria Vescovo, Markus Eckstein

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  • Effectiveness and safety of enfortumab vedotin and pembrolizumab in a real-world patient population with urothelial carcinoma: results from a multi-institutional cohort (GUARDIANS).

    Cancer immunology, immunotherapy : CII

    Authors: Stefanie Zschäbitz, Irfan Bhatti, Jozefina Casuscelli, Ludwig Otto Pachmayr, Thomas Büttner, Thomas Elegeert, Nina Holzwarth, Severin Rodler, Martin Hennig, Emily Rinderknecht, Muammar Dib, Katrin Schlack, Christopher Darr, Anna-Lisa Volk, Philipp Schmucker, Friedemann Zengerling, Pia Paffenholz, Joschka Heil, Eva Erne, Subhajit Mandal, Frederik Wessels, Thea Maria Busse, Daniel Seidl, Susan Foller, Alexander Höllein, Tim Nestler, Christian Gratzke, Louis Rhode, Jakob Kohler, Günter Niegisch, Anna Katharina Seitz, Julia Heinzelbecker, Niklas Klümper, Margitta Retz, Viktor Grünwald, Can Aydogdu, Marco Julius Schnabel

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  • Spatial Multiomics Reveal Insights Into ADC Efficacy.

    European journal of immunology

    Authors: Osman Goni, Niklas Klümper, Maria Del Mar Muñiz Moreno, Markus Eckstein, Christoph Kuppe

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