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Dr. Niklas Klümper

Member

Department of Urology and Institute of Experimental Oncology

niklas.kluemper@ukbonn.de

+49 228 28751394

Website

PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • Membranous expression of target protein is required for ADC response in urothelial cancer.

    European urology

    Authors: Niklas Klümper, Johannes Brägelmann, Veronika Bahlinger, Arndt Hartmann, Viktor Grünwald, Christoph Kuppe, Michael Hölzel, Markus Eckstein

  • Exploring membranous NECTIN-4 expression patterns and enfortumab vedotin response in prostate cancer.

    Journal of cellular and molecular medicine

    Authors: Richard Weiten, Marit Bernhardt, Max Niemann, Glen Kristiansen, Viktor Grünwald, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Niklas Klümper, Philipp Krausewitz

  • Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.

    Cancer medicine

    Authors: Richard Weiten, Max Niemann, Eduard Below, Lea L Friker, Damian J Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper

All publications by Dr. Niklas Klümper