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Dr. Niklas Klümper


Department of Urology and Institute of Experimental Oncology

+49 228 28751394


PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • Bellmunt risk score as a survival predictor in patients with metastatic castration-resistant prostate cancer.

    The Prostate

    Authors: Thomas Büttner, Niklas Klümper, Richard Weiten, Philipp Lossin, Stefan Latz, Carolin Jacobs, Manuel Ritter, Stefan Hauser, Jörg Ellinger, Philipp Krausewitz

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  • The Role of Microsatellite Instability/DNA Mismatch Repair Deficiency and Tumor Mutational Burden as Biomarkers in Predicting Response to Immunotherapy in Castration-resistant Prostate Cancer.

    European urology

    Authors: Niklas Klümper, Viktor Grünwald, Arndt Hartmann, Michael Hölzel, Markus Eckstein

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  • Kick-Starting Molecular Theranostics in Renal Cell Carcinoma.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Authors: Viktor Grünwald, Boris Hadschik, Niklas Klümper, Ken Herrmann

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