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Dr. Niklas Klümper

Member

Department of Urology and Institute of Experimental Oncology

niklas.kluemper@ukbonn.de

+49 228 28751394

Website

PD Dr. med. Niklas Klümper, an advanced clinician-scientist in the ACCENT program at the University Hospital Bonn, focuses on uro-oncology and aims to improve treatment response predictions for targeted therapies, leading to more personalized approaches for uro-oncological diseases. His team has pioneered the prediction of immune checkpoint blockade responses through the analysis of longitudinal inflammatory markers, contributing to the field of immuno-oncology. They are also investigating the mechanisms of resistance to antibody-drug conjugates in patients with metastatic urothelial carcinoma, an emerging area of oncological therapies, and aim to improve precision oncology by tailoring treatment to the molecular profile of patients.

Niklas Klümper

Recent publications

  • Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy.

    Scientific reports

    Authors: Annemarie Uhlig, Angelika Mattigk, Marcus Sondermann, Benedikt Hoeh, Cristina Cano Garcia, Niklas Klümper, Alexander Cox, Oliver Hahn, Philipp Schmucker, Luka Flegar, Jonathan Vollemaere, Friedemann Zengerling, Severine Banek, Jörg Ellinger, Johannes Huber, Philip Zeuschner, Charis Kalogirou, Kati Erdmann

  • CD3 and PD-L1 tissue expression have synergistic value in head and neck squamous cell carcinoma prognosis.

    Translational oncology

    Authors: Adrian V Witzleben, Romain Remark, Christian Idel, Julika Ribbat-Idel, Rosemarie Krupar, Andreas Schröck, Niklas Klümper, Johannes Doescher, Andrew G Sikora, Tsima Abou Kors, Julius M Vahl, Matthias Brand, Michael Sonntag, Cornelia Brunner, Thomas K Hoffmann, Sven Perner, Sacha Gnjatic, Simon Laban

  • Bellmunt Risk Score as a Prognostic Tool in Metastatic Castration-Resistant Prostate Cancer Survival.

    JAMA network open

    Authors: Thomas Büttner, Niklas Klümper, Jörg Ellinger, Manuel Ritter, Philipp Krausewitz

All publications by Dr. Niklas Klümper