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Publications

featured publications

  • [From nontargeted to precision oncology: predictive biomarkers and targeted therapies in advanced urothelial carcinoma].

    Urologie (Heidelberg, Germany)

    Authors: Günter Niegisch, Stefanie Zschäbitz, Markus Eckstein, Niklas Klümper

  • Integrating C-reactive protein flare and early MRI dynamics for enhanced prediction of immunotherapy response.

    Journal for immunotherapy of cancer

    Authors: Daniel Navarro-Garcia, Francesco Grussu, Christina Zatse, Niklas Klümper, Carlos Macarro, Alberto Hernando-Calvo, Marta Sanz, Maria Vieito, Irene Braña, Oriol Mirallas, Guzmán Alonso, Vladimir Galvao, Giulia Pretelli, Julia Lostes, Arjun Oberoi, Rodrigo Toledo, Paolo Nuciforo, Elena Garralda, Raquel Perez-Lopez

  • [Pathological Risk Stratification of Non-Muscle-Invasive and Muscle-Invasive Urothelial Carcinoma for Optimal Therapeutic Decision-Making].

    Aktuelle Urologie

    Authors: Fabienne Lange, Nadine Therese Gaisa, Christian Bolenz, Niklas Klümper, Florian Roghmann, Markus Eckstein

  • Can NaCl predict or even enhance responses to immunotherapy in cancer?

    European journal of cancer (Oxford, England : 1990)

    Authors: Jonas Saal, Michael Hölzel, Niklas Klümper

  • On-treatment modified Glasgow Prognostic Score (mGPS) in hepatocellular carcinoma treated with atezolizumab and bevacizumab provides prognostic information.

    Frontiers in immunology

    Authors: Tessa Hattenhauer, Rebekka Mispelbaum, Annkristin Heine, Katjana Schwab, Peter Brossart, Niklas Klümper, Jonas Saal

  • TROP-2 overexpression in papillary renal cell carcinoma supports its potential as a therapeutic target for antibody-drug-conjugate therapy.

    World journal of urology

    Authors: Carolina Kessler, Melanie von Brandenstein, Niklas Klümper, Philipp Krausewitz, Enno Storz, Constantin Rieger, Laurenz Sperber, Pia Paffenholz, Yuri Tolkach, Ralph Wirtz, Markus Eckstein, Axel Heidenreich, Richard Weiten

  • NaCl and urea modulate CD8+ T cell survival, renal accumulation and response to BK virus.

    JCI insight

    Authors: Peyman Falahat, Adrian Goldspink, Lucia Oehler, Jessica Schmitz, Julia Miranda, Islem Gammoudi, Jan Hinrich Bräsen, Niklas Klümper, Olena Babyak, Christian Kurts, Herrmann Haller, Marieta Toma, Sibylle von Vietinghoff

  • AI allows pre-screening of FGFR3 mutational status using routine histology slides of muscle-invasive bladder cancer.

    Nature communications

    Authors: Pierre-Antoine Bannier, Charlie Saillard, Philipp Mann, Maxime Touzot, Charles Maussion, Christian Matek, Niklas Klümper, Johannes Breyer, Ralph Wirtz, Danijel Sikic, Bernd Schmitz-Dräger, Bernd Wullich, Arndt Hartmann, Sebastian Försch, Markus Eckstein

  • Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy.

    JAMA oncology

    Authors: Jonas Saal, Markus Eckstein, Manuel Ritter, Peter Brossart, Julian Luetkens, Jörg Ellinger, Viktor Grünwald, Michael Hölzel, Niklas Klümper

  • C-Reactive Protein Facilitates Premetastatic Niche Formation in the Lungs.

    Cancer research

    Authors: Jonas Saal, Niklas Klümper, Michael Hölzel