Apoptotic extracellular vesicle formation via local phosphatidylserine exposure drives efficient cell extrusion.
Developmental cell
View this publicationMember, Steering-Committee Member
Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53127 Bonn
My research focuses on the mechanisms by which cytoplasmic RNA sensors RIG-I like receptors (RLRs) distinguish between viral RNAs and self-RNAs and trigger type I IFNs. Current work examines spontaneous autoimmune symptoms in RLR mutant mice derived via mutagenesis and how RLR-dysregulation causes autoimmune disease. I am also particularly interested in the analysis of immune responses and pathogenesis in virus infection in vivo and autoimmune diseases using mouse models.
Developmental cell
View this publicationScientific reports
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Science (New York, N.Y.)
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