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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Simulation-based inference of cell migration dynamics in complex spatial environments.

    NPJ systems biology and applications

    Authors: Jonas Arruda, Emad Alamoudi, Robert Mueller, Marc Vaisband, Ronja Molkenbur, Jack Merrin, Eva Kiermaier, Jan Hasenauer

  • Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

    Nature communications

    Authors: Linda Klümpen, Aakash Mantri, Maren Philipps, Waldemar Seel, Laura Schlautmann, Mohamed H Yaghmour, Verena Wiemann, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Jan Hasenauer, Thomas Fließwasser, Sven Burgdorf, Christoph Thiele, Peter Stehle, Marie-Christine Simon

  • Persistent Low-Grade Inflammation and Post-COVID Condition: Evidence from the ORCHESTRA Cohort.

    Biomedicines

    Authors: Elisa Gentilotti, Carolina Alvarez Garavito, Anna Górska, Roy Gusinow, Lorenzo Maria Canziani, Pasquale De Nardo, Alessandro Visentin, Maria Giulia Caponcello, Michela Di Chiara, Aline-Marie Florence, Gerolf de Boer, Salvatore Cataudella, The Orchestra Study Group, Gabriel Levy Hara, Adriana Tami, Maddalena Giannella, Cédric Laouénan, Jan Hasenauer, Jesús Rodríguez-Baño, Evelina Tacconelli

All publications by Prof. Dr. Jan Hasenauer