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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Next-generation discovery: empowering organoid research with machine learning, artificial intelligence, and mathematical modeling.

    Trends in biotechnology

    Authors: Sneha Pushpa Ramesan, Jasmitha Boovadira Poonacha, Dilan Pathirana, Simon Merkt, Christian Maass, Jan Hasenauer, Elena S Reckzeh

  • From brown to white: Brown adipose tissue endothelial cells whiten in culture conditions.

    Molecular metabolism

    Authors: Tabea Elschner, Stephan Grein, Jana Sander, Staffan Hildebrand, Lara Heubach, Nina Pannwitz, Maria Mircea, Elba Raimundez, Vasiliki Karagiannakou, Anastasia Georgiadi, Joerg Heeren, Jan Hasenauer, Alexander Pfeifer, Kerstin Wilhelm-Jüngling

  • Endothelial ADGRF5(GPR116) governs vascular adaptation required for sustained thermogenic remodeling of brown adipose tissue.

    Molecular metabolism

    Authors: Rabih El-Merahbi, Vasiliki Karagiannakou, Ronja Kardinal, Lea Seep, Richard Lindner, Michelle Ynonne Jäckstein, Staffan Hildebrand, Mersiha Hasic, Eylül Korkmaz, Ankush Kumar Jha, Aspasia Thodou Krokidi, Kenneth Dyar, Felix Meissner, Stephan Grein, Jörg Heeren, Martin Klingenspor, Alexander Pfeifer, Jan Hasenauer, Dagmar Wachten, Stephan Herzig, Anastasia Georgiadi

All publications by Prof. Dr. Jan Hasenauer