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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • The parameter estimation tables (PEtab) format version 2.

    Journal of integrative bioinformatics

    Authors: Dilan Pathirana, Fabian Fröhlich, Sebastian Persson, Frank T Bergmann, Matthias König, Paul F Lang, Severin Bang, Svenja Kemmer, Jan Hasenauer, Daniel Weindl

  • Quantitative modelling of P-TEFb mediated CTD phosphorylation identifies local cooperativity.

    PLoS computational biology

    Authors: Aaron Callenbach, Domagoj Dorešić, Robert Düster, Vanessa Nakonecnij, Erika Dudkin, Matthias Geyer, Jan Hasenauer

  • Coupled epidemiological and wastewater modeling at the urban scale: A case study for Munich.

    iScience

    Authors: Julia Bicker, Natalie Tomza, Karina Wallrafen-Sam, Nina Schmid, Andreas F Hofmann, Sascha Korf, Alain Schengen, Jasmin Javanmardi, Andreas Wieser, Martin J Kühn, Jan Hasenauer

All publications by Prof. Dr. Jan Hasenauer