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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Adipose ILC2s depend on acetyl-CoA carboxylase 1 to maintain metabolic health.

    Cell metabolism

    Authors: Fotios Karagiannis, Maria Rafailia Theodorou, Fabian Nikolka, Maria Doverman, Dhruvi Shah, Chantal Wientjens, Timothy R McCulloch, Ronja Kardinal, David Colon, Jelena Zurkovic, Jiangyan Yu, Julia Anna Noras, Patricia Weiss, Roman Rombo, Tim Sparwasser, Zeinab Abdullah, Felix Meissner, Christoph Thiele, Jan Hasenauer, Dagmar Wachten, Karsten Hiller, Christoph Wilhelm

  • Scalable branch-and-bound model selection with non-monotonic criteria including AIC, BIC and Mallows's C.

    Mathematical biosciences

    Authors: Jakob Vanhoefer, Antonia Korner, Domagoj Doresic, Jan Hasenauer, Dilan Pathirana

  • MEmilio: a high performance Modular EpideMIcs simuLatIOn software for multi-scale and comparative simulations of infectious disease dynamics.

    Scientific reports

    Authors: Julia Bicker, Carlotta Gerstein, David Kerkmann, Sascha Korf, René Schmieding, Anna Wendler, Henrik Zunker, Daniel Abele, Maximilian Betz, Khoa Nguyen, Lena Plötzke, Kilian Volmer, Agatha Schmidt, Nils Waßmuth, Patrick Lenz, Daniel Richter, Hannah Tritzschak, Ralf Hannemann-Tamas, Julian Litz, Paul Johannssen, Marielena Borges, Annika Jungklaus, Manuel Heger, Annalena Lange, Elisabeth Kluth, Kathrin Rack, Vincent Wieland, Jonas Arruda, Sebastian C Binder, Margrit Klitz, Martin Siggel, Manuel Dahmen, Achim Basermann, Michael Meyer-Hermann, Jan Hasenauer, Martin J Kühn

All publications by Prof. Dr. Jan Hasenauer