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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Machine Learning Methods for Precision Dosing in Anticancer Drug Therapy: A Scoping Review.

    Clinical pharmacokinetics

    Authors: Olga Teplytska, Moritz Ernst, Luca Marie Koltermann, Diego Valderrama, Elena Trunz, Marc Vaisband, Jan Hasenauer, Holger Fröhlich, Ulrich Jaehde

  • Top publication

    An amortized approach to non-linear mixed-effects modeling based on neural posterior estimation

    Proceedings of Machine Learning Research

    Authors: Jonas Arruda, Yannik Schälte, Clemens Peiter, Olga Teplytska, Ulrich Jaehde, Jan Hasenauer

  • Retro Mode Imaging for Detection and Quantification of Sub-RPE Drusen and Subretinal Drusenoid Deposits in Age-Related Macular Degeneration.

    Journal of clinical medicine

    Authors: Marlene Saßmannshausen, Leyla Sautbaeva, Leon Alexander von der Emde, Marc Vaisband, Kenneth R Sloan, Jan Hasenauer, Frank G Holz, Thomas Ach

All publications by Prof. Dr. Jan Hasenauer