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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Latent transition analysis for longitudinal studies of post-acute infection syndromes.

    Nature communications

    Authors: Roy Gusinow, Anna Górska, Lorenzo Maria Canziani, Iris Lopes-Rafegas, Carolina Alvarez Garavito, Adriana Tami, Elisa Gentilotti, Elisa Sicuri, Cédric Laouénan, Jade Ghosn, Aline-Marie Florence, Nadhem Lahfej, Fulvia Mazzaferri, Lidia Del Piccolo, Maddalena Giannella, Alice Toschi, Michela Di Chiara, Maria Giulia Caponcello, Zaira R Palacios-Baena, Karin I Wold, Elisa Rossi, Evelina Tacconelli, Jan Hasenauer

  • Near-Infrared Fluorescence Lifetime Imaging Microscopy Reveals Loss of RPE Cell Body Polarity in Age-Related Macular Degeneration.

    Investigative ophthalmology & visual science

    Authors: Katharina Wall, Sebastian Fritsch, Marc Vaisband, Jan Hasenauer, Niko Schwenzer, Leon von der Emde, Anna Sophia Jauch, Frank G Holz, Christine A Curcio, Thomas Ach

  • Simulation-based inference of cell migration dynamics in complex spatial environments.

    NPJ systems biology and applications

    Authors: Jonas Arruda, Emad Alamoudi, Robert Mueller, Marc Vaisband, Ronja Molkenbur, Jack Merrin, Eva Kiermaier, Jan Hasenauer

All publications by Prof. Dr. Jan Hasenauer