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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

+49 228 7369446


Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Personalized Lens Correction Improves Quantitative Fundus Autofluorescence Analysis.

    Investigative ophthalmology & visual science

    Authors: Leon von der Emde, Geena C Rennen, Marc Vaisband, Jan Hasenauer, Raffael Liegl, Monika Fleckenstein, Maximilian Pfau, Frank G Holz, Thomas Ach

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  • Publication categories: Top publication

    TGF-β specifies T versus T17 cell fates in murine CD4 T cells through c-Maf.

    Science immunology

    Authors: Yinshui Chang, Luisa Bach, Marko Hasiuk, Lifen Wen, Tarek Elmzzahi, Carlson Tsui, Nicolás Gutiérrez-Melo, Teresa Steffen, Daniel T Utzschneider, Timsse Raj, Paul Jonas Jost, Sylvia Heink, Jingyuan Cheng, Oliver T Burton, Julia Zeiträg, Dominik Alterauge, Frank Dahlström, Jennifer-Christin Becker, Melanie Kastl, Konstantinos Symeonidis, Martina van Uelft, Matthias Becker, Sarah Reschke, Stefan Krebs, Helmut Blum, Zeinab Abdullah, Katrin Paeschke, Caspar Ohnmacht, Christian Neumann, Adrian Liston, Felix Meissner, Thomas Korn, Jan Hasenauer, Vigo Heissmeyer, Marc Beyer, Axel Kallies, Lukas T Jeker, Dirk Baumjohann

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  • Processivity and specificity of histone acetylation by the male-specific lethal complex.

    Nucleic acids research

    Authors: Anna E Kiss, Anuroop V Venkatasubramani, Dilan Pathirana, Silke Krause, Aline Campos Sparr, Jan Hasenauer, Axel Imhof, Marisa Müller, Peter B Becker

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