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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Continuous Circulation of Hepatitis E and A Viruses During COVID-19 Pandemic Lockdowns in Munich, Germany-Experience from Three Years of Wastewater Surveillance.

    Microorganisms

    Authors: Jasmin Javanmardi, Mathias Schemmerer, Karina Wallrafen-Sam, Jessica Neusser, Raquel Rubio-Acero, Michael Hoelscher, Thomas Kletke, Bernhard Boehm, Michael Schneider, Elisabeth Waldeck, Martin Hoch, Merle M Böhmer, Christof Geldmacher, Jan Hasenauer, Jürgen J Wenzel, Andreas Wieser

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  • A dynamic model for Waddington's landscape accounting for cell-to-cell communication.

    Mathematical biosciences

    Authors: Simon Merkt, Lara Fuhrmann, Erika Dudkin, Andreas Schlitzer, Barbara Niethammer, Jan Hasenauer

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  • PEtab.jl: Advancing the Efficiency and Utility of Dynamic Modelling.

    Bioinformatics (Oxford, England)

    Authors: Sebastian Persson, Fabian Fröhlich, Stephan Grein, Torkel Loman, Damiano Ognissanti, Viktor Hasselgren, Jan Hasenauer, Marija Cvijovic

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